Predictors of Outcomes in Traumatic Brain Injury

Baum, Justin; Entezami, Pouya; Shah, Kavit; Medhkour, Azedine

doi:10.1016/j.wneu.2015.12.012

Cited by 58 publications

(46 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Cause of injury had statistically significant effect on management (P = 0.02) and statistically non-significant effect on outcome (p = 0.4), as shown in table (3,4) and figure (5).…”

Section: Resultsmentioning

confidence: 97%

See 1 more Smart Citation

Management and outcome of moderate head trauma: our experience

Alshaimaa¹,

Sultan²,

Zakaria³

et al. 2018

Romanian Neurosurgery

View full text Add to dashboard Cite

Abstract:Objective: The aim of this study is to follow up patients with moderate head trauma who were admitted to Mansoura University Hospital in the period from 1 Dec. 2015 to 30 Jul. 2016 until discharge and determine the outcome of head trauma. Material and Methods: This prospective study were conducted on all patients with moderate head trauma admitted to Mansoura Emergency Hospital during the period from 1 Dec. 2015 to 30 Jul. 2016 with exclude Polytrauma, bleeding disorders, severe liver and kidney disease patients. Results: In this study, we correlated different risk factors with management and with outcome. Management may be surgical or conservative and outcome may be alive or dead. We have 60 patients with 17 cases (28.3%) were treated surgically and 43 cases (71.6%) were treated conservatively. According to outcome 36 cases (60%) were alive and 24 cases (40%) died, all cases managed in ICU. According to sex, 10 cases (17%) were female and 50 cases were male (83%) with statistically nonsignificant effect on outcome (P = 0.7) and management (P =0.7). road traffic accidents is most common cause of injury with 33 cases (55%), and Cause of injury had statistically significant effect on management (P = 0.02) and statistically non-significant effect on outcome (p = 0.4). GCS on admission had no statistically significant effect on management (P=0.8) and outcome (P=0.1) with mean of 10.1±1.2 and GCS on discharge had no statistically significant effect on management (P=0.6). Conclusion: There were significant effect of age of patients, systemic diseases (such as DM, HTN, chronic kidney diseases, and chronic liver diseases), type of lesions (especially SDH, SAH), and serum electrolytes (especially serum Sodium) on outcome which determined by GCS at discharge, length of hospital stay, and the state of the patient at discharge.

show abstract

“…Cause of injury had statistically significant effect on management (P = 0.02) and statistically non-significant effect on outcome (p = 0.4), as shown in table (3,4) and figure (5).…”

Section: Resultsmentioning

confidence: 97%

“…CLD, CKD, epilepsy, cardiac diseases. These cases might have only one disease or might have more than one systemic diseases, as shown in table (5).…”

Section: Resultsmentioning

confidence: 99%

Management and outcome of moderate head trauma: our experience

Alshaimaa¹,

Sultan²,

Zakaria³

et al. 2018

Romanian Neurosurgery

View full text Add to dashboard Cite

show abstract

“…15 la mortalidad varía entre un 40l66%. Se puede determinar que aunque la mortalidad no es comparable con otras series, la severidad en la discapacidad es la que genera el mayor compromiso entre los sobrevivientes y, a través de estos dos indicadores se puede ver el impacto que representa el resultado conjunto terapeutico que va desde una atención prehospitalaria hasta la aplicación de recomendaciones internacionales para manejo de TCE y el respectivo punto de comparación para nuevos protocolos.…”

Section: Discusionunclassified

Estado Funcional De Los Pacientes Con Trauma Craneo Encefalico Criticamente Enfermos

Botache¹,

Sanjuán²,

Rubio³

et al. 2017

Panamerican Journal of Trauma, Critical Care &Amp; Emergency Surgery

View full text Add to dashboard Cite

Antecedentes: El trauma craneoencefálico (TCE) continúa siendo la principal causa de morbimortalidad entre pacientes con trauma, la discapacidad y el compromiso cognitivo corresponde a la principal afectación configurando pronóstico a largo plazo. Materiales y métodos:Se realizó un estudio prospectivo tipo cohortes/casos y controles donde se incluyeron los pacientes con TCE severo (Escala Coma de Glasgow <8 y/o TAC anormal) que ingresaron a la unidad de cuidados intensivos Adultos durante 6 meses; se buscó determinar los desenlaces relacionados con el TCE en términos de mortalidad y discapacidad.Resultados: Se encontraron 32 pacientes, más del 90% hombres, la mayoría con estabilidad hemodinámica al ingreso, se practicó neurocirugía en el 40% de los pacientes, aunque todos tenían indicación de monitoria de presión intracraneana solo se realizó en el 6% de los pacientes. El puntaje en la escala de desenlaces de Glasgow presento una mediana de 3 (RIC = 225 puntos). Se clasifico la severidad de la discapacidad en buena recuperacion 9,3%, discapacidad moderada 31,25%, discapacidad severa-muerte hasta en un 25%. Se determino que que un puntaje en la ECG se relacionaba con un GOS mas bajo; la neumonía aspirativa fue la principal complicación extracraneal, la mortalidad global correspondió a un 34.4%. Conclusión:El TCE continua afectando de manera especial a las poblaciones jóvenes, con una alta incidencia de consecuencias discapacitantes y alta mortalidad, los centros de trauma deben implementar protocolos mas estrictos para promover la prevención y reforzar la aplicación de recomendaciones mundiales para mejores resultados en términos supervivencia y calidad de vida.Significancia clinica: El trauma craneoencefálico, continua configurándose como la principal causa de morbimortalidad y discapacidad en adultos jovenes, con esta investigación se busca conocer y describir los datos epidemiológicos relevantes con respecto al desenlace de dicho trauma, conocimiento que es clave en el proceso de enseñanza buscando ofrecer mejores y mas efectivos abordajes en el momento de verse enfrentado a un trauma craneoencefálico.Palabras claves: Discapacidad, El trauma craneoencefálico, Escala pronostica de Glasgow, Monitoria de pic, Unidad de cuidados intensivos. ABSTRACTIntroduction: Traumatic brain injury (TBI) remains to be the leading cause of morbidity and mortality among patients with trauma, disability and neurocognitive commitment corresponds to the main affectation and set the long-term prognosis of these patients. Materials and methods:It was performed a prospective cohort/cases and controls study, where all the patients with severe TBI (Glasgow Coma Scale (GCS) < 8 and/or abnormal CT scan) were admitted into the adult intensive care unit (ICU) for 6 months to determine the outcomes related to TBI in terms of mortality and disability.Results: Thirty-two patients, more than 90% men, most with hemodynamic stability at admission; neurosurgery was practiced in 40% of patients. Although all had indication of intracranial pressure (...

show abstract

“…Traumatic brain injury (TBI) is a common cause of death in Intensive Care Units and Emergency ward primarily caused by RTA (Road Tra c Accidents), followed by falls and assaults with severe traumatic brain injury (STBI) (GCS ≤ 8) estimated as a signi cant cause of neurological morbidity and mortality accounting for 1.5 million deaths annually (1)(2)(3)(4). According to different studies done in Uganda, TBI accounted for most of the neurosurgical admissions at 87.0% and mortality rate of 13.0% (5) while the prevalence of STBI was at 9.0% (6).…”

Section: Introductionmentioning

confidence: 99%

“…Outcomes of STBI are associated with many factors like age, co-morbidities, alcohol abuse, low socioeconomic status, educational status and cause of injury (1). Primary and secondary central nervous system complications were the cause of mortality in 70% of patients admitted within 24 hours of the injury (11).…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Glasgow Outcome Scale score of severe head injury in Mbarara regional referral hospital: A retrospective study

Odwar¹,

Okidi²,

Kayanga³

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: Traumatic brain injury (TBI) is a common cause of death in the Intensive care units and emergency departments with an estimated annual global mortality of 1.5 million people as a result of severe TBI. The prevalence of TBI varies according to regions. Despite this, there is limited data on the outcomes of patients following severe traumatic brain injury in southwestern Uganda. Herein, we studied the prevalence and outcome of severe traumatic brain injury at Mbarara Regional Referral Hospital (MRRH) at discharge.Methods: A retrospective chart review of all TBI over six months (August 2016 - February 2017). The primary outcome was the Glasgow Outcome Scale (GOS) score at discharge. A favorable outcome was either good recovery or moderate disability while unfavorable outcome was severe disability, persistent vegetative state or death. Bivariate and multivariate logistic regression analyses were used to determine the factors associated with GOS score at discharge. Data were analyzed using STATA v13.0.Results: A total of 196 hospital records of TBI patients were reviewed, 80 (40.8%) patients had severe TBI, with the average length of hospital stay at 4.3 ± 2.9 days. The mean patients' age was 35 ± 14 years with the most affected age group being 18 - 34 years (58.8%). The GOS score at discharge were; death (42.5%), persistent vegetative state (0%), severe disability (1.3%), moderate disability (3.8%) and good recovery (52.5%). Pupil size and response had a dose-response relationship with unfavorable outcome when both pupils were dilated and non-reactive to light and had a higher odd ratio (OR=6.05) and strongly associated with unfavorable outcome (p=0.011). However, surgery and seizure prophylaxis were significantly associated with favorable outcome (p=0.033), (p=0.016) and a lesser odd ratio (OR=0.29),(OR=0.31) of having unfavorable outcome respectively. Conclusion: Mbarara regional referral hospital, the prevalence of STBI is still high. Both surgery and seizure prophylaxis were associated with favorable outcome at discharge. However, unfavorable outcome was mainly seen amongst patients who develop a complication.

show abstract

Predictors of Outcomes in Traumatic Brain Injury

Cited by 58 publications

References 36 publications

Management and outcome of moderate head trauma: our experience

Management and outcome of moderate head trauma: our experience

Estado Funcional De Los Pacientes Con Trauma Craneo Encefalico Criticamente Enfermos

Prevalence and Glasgow Outcome Scale score of severe head injury in Mbarara regional referral hospital: A retrospective study

Contact Info

Product

Resources

About