Predictors of spontaneous bleeding in Dengue

Shivbalan, So; Anandnathan, K; Balasubramanian, Sundaram; Datta, Manjula; Amalraj, Edwin

doi:10.1007/bf02725653

Cited by 52 publications

(46 citation statements)

References 8 publications

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“…Particularly, adult patients may present with bleeding than children and bleeding manifestation may occur in the absence of plasma leakage. (4) This observation raises 2 questions that bleeding and plasma leakage may be 2 independent complications. Thrombocytopenia is strongly associated with bleeding.…”

Section: Discussionmentioning

confidence: 99%

Correlational Study of Thrombocytopenia and Bleeding Complications in Dengue

Venkataramanappa¹,

Rangaswamaiah²,

Nagaraj³

2017

jemds

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Section: Discussionmentioning

confidence: 99%

Correlational Study of Thrombocytopenia and Bleeding Complications in Dengue

Venkataramanappa¹,

Rangaswamaiah²,

Nagaraj³

2017

jemds

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“…Bleeding manifestations are highly variable and do not always correlate with the laboratory abnormalities in the coagulation profile. Factors like mild degree of disseminated intravascular coagulation (DIC), hepatic derangement and thrombocytopenia act synergistically to cause bleeding in dengue patient 13 . Severe bleeding is related to severe thrombocytopenia 14 .…”

Section: Discussionmentioning

confidence: 99%

Unusual yet isolated oral manifestations of persistent thrombocytopenia: a rare case report

Byatnal¹,

Mahajan²,

Koppal³

et al. 2013

Braz. J. Oral Sci.

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Patients with platelet-mediated disorders often present clinical manifestations of bruising and bleeding. Although these changes are detected most frequently on the skin, the oral cavity also may exhibit signs of bleeding. In this report, we describe a patient who presented isolated oral features of hemorrhagic bullae with bleeding, indicative of a bleeding disorder. Results of laboratory tests revealed severe thrombocytopenia and a careful history disclosed dengue fever as the cause. The importance of recognizing the oral manifestations of thrombocytopenia is highlighted here, since the oral cavity is a frequent site of hemorrhage and could be the only manifestation of the disease.

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“…Bleeding in dengue can be caused due to Disseminated Intravascular Coagulation (DIC), hepatic derangement and also due to severe thrombocytopenia. 2 In the present study, the patients have been classified into dengue without warning signs, dengue with warning signs and severe dengue according to the WHO bulletin, 2009. 3 Prophylactic platelet transfusion is recommended in patients with platelet count less than 10000/cumm and platelet transfusion is advised in patients with associated bleeding or hemorrhagic manifestation along with thrombocytopenia (count more than 10000/cumm).…”

Section: Introductionmentioning

confidence: 99%