Predictors of Survival and Favorable Functional Outcomes After an Out-of-Hospital Cardiac Arrest in Patients Systematically Brought to a Dedicated Heart Attack Center (from the Harefield Cardiac Arrest Study)

Iqbal, Mohammad; Al-Hussaini, Abtehale; Rosser, Gareth; Salehi, Saleem; Phylactou, Maria; Rajakulasingham, Ramyah; Patel, Jayna; Elliott, Katharine; Mohan, Poornima; Green, Rebecca; Whitbread, Mark; Smith, Robert; Ilsley, Charles

doi:10.1016/j.amjcard.2014.12.033

Cited by 39 publications

(38 citation statements)

References 29 publications

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“…In these patients, about 90% will eventually die or have serious neurological sequelae [22], which indicates that we have a long road ahead with respect to improving survival [23]. …”

Section: Discussionmentioning

confidence: 99%

Mortality after out-of-hospital cardiac arrest in a Spanish Region

et al. 2017

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AimsTo determine out-of-hospital cardiac arrest mortality in the province of Alicante (Spain) and its associated factors.MethodsCross-sectional observational study of all patients who received cardiopulmonary resuscitation (CPR) by the Emergency Medical Services (EMS) (n = 422) in the province of Alicante in 2013. To determine associated factors, a binary logistic regression model was constructed. Primary outcome: death before arriving at the hospital. Predictive variables: gender, age, artificial respiration, prior functional status, asystole, cardiogenic aetiology, bystander CPR, time from the cardiac arrest to the arrival of the EMS and location of cardiac arrest.ResultsThere were 337 deaths (79.9%; 95% CI: 76.0–83.7%). Factors independently associated (p<0.05) with death were: male gender (OR = 2.11; 95% CI: 1.20–3.72; p = 0.010), asystole (OR = 1.99, 95% CI: 1.17–3.39; p = 0.012), cardiac arrest at home (OR = 2.44; 95% CI: 1.42–4.18; p = 0.001) and an increased time between arrest and EMS arrival (OR = 1.05, 95% CI: 1.01–1.09, p = 0.009). Having a worse prior functional status had a tendency towards significance (OR = 0.56, 95% CI: 0.31–1.02, p = 0.059).ConclusionsMortality was high. The associated factors were: male gender, asystole, worse prior functional status, longer time from the cardiac arrest to the arrival of the EMS and having the cardiac arrest at home. The clearly negative impact of experiencing a cardiac arrest at home necessitates modifying training policies in Spain. These policies should be focused on providing information about CPR in schools in order to decrease the mortality of these events.

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“…In these patients, about 90% will eventually die or have serious neurological sequelae [22], which indicates that we have a long road ahead with respect to improving survival [23]. …”

Section: Discussionmentioning

confidence: 99%

Mortality after out-of-hospital cardiac arrest in a Spanish Region

et al. 2017

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“…18 However, a limitation of the latter study was that only 59% of the patients had ventricular arrhythmia-induced cardiac arrest, which could influence the results as patients presenting with non-shockable rhythm have a worse prognosis. 19 Hence, limited data are available regarding the value of measuring NT-proBNP levels in patients with OHCA due to ventricular tachycardia or fibrillation (OHCA-VT/VF). Moreover, it is not known whether the combination of NT-proBNP and high-sensitivity troponin T (hs-TnT), which could provide complementary information on acute myocardial infarction 20 and prognosis, 21 may further improve risk prediction in OHCA-VT/VF.…”

Section: Introductionmentioning

confidence: 99%

NT-proBNP in patients with out-of-hospital cardiac arrest: Results from the FINNRESUSCI Study

et al. 2016

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“…Clinical care is provided by Emergency Medical Technician (EMT) level staff trained in intermediate life support that incorporates use of the i‐gel SGA device, and paramedics trained in advanced life support incorporating ETI in some cases. Since 2011, patients with ROSC and evidence of ST elevation myocardial infarction (STEMI) or presumed new onset left bundle branch block (LBBB) following out‐of‐hospital cardiac arrest undergo direct transfer to specialist HAC equipped to provide PPCI . These referrals are made autonomously by ambulance clinicians directly from the scene based on clinical presentation and interpretation of the prehospital 12 lead electrocardiograph (ECG) …”

Section: Methodsmentioning

confidence: 99%