Predictors of ventricular tachyarrhythmia in high-risk myocardial infarction patients treated with primary coronary intervention

Abstract

Background. We investigated the association between clinical characteristics, angiographic data and ventricular arrhythmia in patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). Methods. In patients with STEMI (n=225), a Holter analysis was performed the first 12 hours after primary PCI.Results. A total of 151 (66%) patients had ≥1 episode of ventricular tachycardia (VT). Age <70 years (RR 4.9, 95% CI 1.8 to 12.7), TIMI 0-1 pre-PCI (RR 2.6, 95% CI 1.1 to 6.1) and peak CK (RR 3.5, 95% CI 1.9 to 5.8) were independent predictors of VT. One-year mortality was 7%, no association between mortality and presence of early VT was found. Conclusion. Ventricular tachycardia is common

Hyperglycemia and risk of ventricular tachycardia among patients hospitalized with acute myocardial infarction

“…Ventricular tachycardia frequently complicates the clinical course of patients hospitalized with acute myocardial infarction and is associated with worse in-hospital and long-term outcomes, especially sudden cardiac death [ 1 , 2 ]. The development of ventricular tachycardia (VT) in patients with an acute myocardial infarction (AMI) is typically associated with a larger infarct, ST segment elevation, left ventricular dysfunction, and more extensive underlying coronary artery disease [ 3 , 4 ].…”

Correlation of Prolonged Corrected QT Interval With Ventricular Arrhythmias and In-Hospital Mortality Among ST-Elevation Myocardial Infarction Patients: A Mystique or Lucidity?

“…Moreover, Literature reports that patients receiving thrombolytic therapy have an increased likelihood of developing VAs than patients that received reperfusion therapy via PCI [9]. Nonetheless, VAs can still occur during the acute phase of STEMI even with early and effective reperfusion therapy [15]. This illustrates that the QTc interval is an important risk factor of VAs in STEMI patients leading to an increased mortality rate.…”

Modern clinical retrospective on ventricular rhythm disturbances in acute myocardial infarction: Latest treatment mode according to the valid recommendations

“…Most episodes of VT in STEMI patients occur within the fi rst 48 hours. Studies have shown that the main predictors for the occurrence of early VT in patients with STEMI are age, the absence of anterograde epicardial fl ow in the infarct artery before PCI and larger infarction zone [2]. Other studies suggest that low systolic blood pressure aft er primary PCI is the main predictor of early VT/ VF [2,14].…”

“…Studies have shown that the main predictors for the occurrence of early VT in patients with STEMI are age, the absence of anterograde epicardial fl ow in the infarct artery before PCI and larger infarction zone [2]. Other studies suggest that low systolic blood pressure aft er primary PCI is the main predictor of early VT/ VF [2,14]. When the "sustained "VT occurs later in STEMI (over 24 hours), it is associated with increased mortality in the fi rst 30 days of follow-up compared with patients who did not have "sustained" VT [15].…”

“…Occurrence of ventricular rhythm disturbances in acute myocardial infarction usually indicates the presence of extensive myocardial damage at a reduced left ventricular ejection fraction, and not infrequently in the formation of an aneurysm of the left ventricle [2]. Th e results of the study before the era of primary percutaneous intervention in acute myocardial infarction indicate poor prognosis in patients with ventricular arrhythmias occurred more than 48 hours from the start of acute myocardial infarction [2,3,4,5].…”