Predominance of Porcine P[23] Genotype Rotaviruses in Piglets with Diarrhea in Northern Thailand

Abstract

Of 131 stool samples collected from piglets with diarrhea in northern Thailand between July 2006 and August 2008, 14 (10.7%) were positive for group A rotavirus. Sequence analysis showed that 13 strains (92.9%) belonged to the rare P[23] genotype combination with G9 or G3 genotypes.

Porcine Rotaviruses: Epidemiology, Immune Responses and Control Strategies

“…The prevalence of porcine RVA in Kenya and Uganda reported in the recent study by Amimo et al of 26.2% [65] was higher compared to the prevalence rates of 6.5%–25.7% reported for samples collected in 2004–2011 in the USA [65], several European countries [75,84,85], Thailand [89], and India [124], but however, lower (32.7%–38.3%) to those observed in Vietnam [74], Brazil [80] and Korea [76]. It was lower than that reported for samples collected in the US in 2009–2011 [69], in asymptomatic pigs in Italy (71.5%) [70] or previously reported for South Africa (84.6%) [123].…”

“…RVA prevalence rates in pigs vary from 3.3% to 67.3% without evidence of seasonality, but with spatio-temporal fluctuations and re-emergence of certain genotypes, including G9 and G1 [67,71,75,76,77,78,79,80,81,82,83,84,85,86,87], with farm-level prevalence reaching 61%–74% [73,74]. Twelve G genotypes (G1 to G6, G8 to G12, and G26) and 16 P genotypes (P[1] to P[8], P[11], P[13], P[19], P[23], P[26], P[27], P[32], and P[34]) of RVA have been associated with pigs [65,67,70,72,73,74,84,88,89,90,91]. However, G3, G4, G5, G9 and G11 were historically considered the most common G genotypes in swine and were usually associated with P[5], P[6], P[7], P[13] and P[28] [16,89,92].…”

“…Twelve G genotypes (G1 to G6, G8 to G12, and G26) and 16 P genotypes (P[1] to P[8], P[11], P[13], P[19], P[23], P[26], P[27], P[32], and P[34]) of RVA have been associated with pigs [65,67,70,72,73,74,84,88,89,90,91]. However, G3, G4, G5, G9 and G11 were historically considered the most common G genotypes in swine and were usually associated with P[5], P[6], P[7], P[13] and P[28] [16,89,92]. …”

Phylogenetic Analyses of the VP4 and VP7 Genes of Porcine Group A Rotaviruses in São Paulo State, Brazil: First Identification of G5P[23] in Piglets

“…Gouvea and Brantly (31) suggest that this phenomenon explains new epidemiological findings and controversial results in studies of the efficacy of vaccines that target these viral agents. The P [23] genotype has been described as predominant in Thailand (16,32) and was isolated from a pig in China (33). Pigs are regarded as important reservoirs for human rotavirus diversification (10,12,28,34).…”

Development of real-time RT-PCR for human metapneumovirus

“…Nucleotide sequences of these two genes are used to classify rotavirus strains into genotypes. To date, 23 G genotypes (VP7) and 32 P genotypes (VP4) have been identified in humans and different animal species Okitsu et al, 2011). Worldwide, 80% of human rotavirus strains result from infections with the P [8] genotype (Santos and Hoshino, 2005).…”