Predominant Mutations of SARS-CoV-2: Their Geographical Distribution and Potential Consequences

Unlu, Sezin; Güçlü, Aylin Üsküdar; Başustaoğlu, Ahmet

doi:10.4274/mjima.galenos.2021.2021.15

Cited by 2 publications

(2 citation statements)

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“…Many mutations in SARS-CoV 2 cause changes in the properties of the virus and affect the response to the pandemic. Preliminary analysis shows that at least one mutation, common to three new worrying variants, appears to increase transmission efficiency (Unlu et al 2021). It is imperative that vaccines are produced as soon as possible and that genetic monitoring needs to be stepped up to detect variations when they first emerge and wander around the world.…”

Section: Covid-19 Mutationsmentioning

confidence: 99%

Photonics enabled intelligence system to identify SARS-CoV 2 mutations

Taha

Al-Jubouri

Mashhadany

et al. 2022

Appl Microbiol Biotechnol

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The COVID-19, MERS-CoV, and SARS-CoV are hazardous epidemics that have resulted in many deaths which caused a worldwide debate. Despite control efforts, SARS-CoV-2 continues to spread, and the fast spread of this highly infectious illness has posed a grave threat to global health. The effect of the SARS-CoV-2 mutation, on the other hand, has been characterized by worrying variations that modify viral characteristics in response to the changing resistance profile of the human population. The repeated transmission of virus mutation indicates that epidemics are likely to occur. Therefore, an early identification system of ongoing mutations of SARS-CoV-2 will provide essential insights for planning and avoiding future outbreaks. This article discussed the following highlights: First, comparing the omicron mutation with other variants; second, analysis and evaluation of the spread rate of the SARS-CoV 2 variations in the countries; third, identification of mutation areas in spike protein; and fourth, it discussed the photonics approaches enabled with artificial intelligence. Therefore, our goal is to identify the SARS-CoV 2 virus directly without the need for sample preparation or molecular amplification procedures. Furthermore, by connecting through the optical network, the COVID-19 test becomes a component of the Internet of healthcare things to improve precision, service efficiency, and flexibility and provide greater availability for the evaluation of the general population. Key points• A proposed framework of photonics based on AI for identifying and sorting SARS-CoV 2 mutations. • Comparative scatter rates Omicron variant and other SARS-CoV 2 variations per country.• Evaluating mutation areas in spike protein and AI enabled by photonic technologies for SARS-CoV 2 virus detection.

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Section: Covid-19 Mutationsmentioning

confidence: 99%

Photonics enabled intelligence system to identify SARS-CoV 2 mutations

Taha

Al-Jubouri

Mashhadany

et al. 2022

Appl Microbiol Biotechnol

View full text Add to dashboard Cite

show abstract

“…The spike protein of SARS-CoV-2 have two subunits; S1 and S2. While S1 is responsible for recognizing and binding ACE-2, S2 is responsible for membrane fusion (Unlu et al, 2021). Due to spike protein's crucial roles, assessing the wide mutational profile of spike protein would be vital for designing vaccines targeting spike protein (Begum et al, 2021).…”

Section: Introductionmentioning

confidence: 99%