Preemptive Analgesia, Regional Anesthesia, and Prevention of Chronic Postoperative Pain

Helander, Erik; Eskander, Jonathan P.; Juneau, Christina; Novitch, Matthew B.; Prabhakar, Amit; DeKerlegand, Amy M.; Cornett, Elyse M.; Kaye, Alan D.

doi:10.1007/978-3-319-74838-2_23

Cited by 6 publications

(6 citation statements)

References 118 publications

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“…There are many studies in which all three methods are used preemptively in inguinal hernia operations [1,11]. However, despite the use of different types of nsaid in previous studies, we could not find any studies in which intravenous dexketoprofen (IVD) was administered preemptively.…”

Section: Introductionmentioning

confidence: 88%

“…In addition to these two technics, intravenous analgesic drug (IVAD) is also used as pharmacological postoperative analgesia method in most clinics [1,10]. Nonsteroidal antiinflammatory drugs (NSAID), paracetamol, cyclooxygenase inhibitors, opioids, glucocorticoids, clonidine, magnesium, gabapentin and pregabalin are used for this purpose [1,10,11]. One of these drugs, dexketoprofen, has been used to provide postoperative analgesia in different surgical procedures [12].…”

Section: Introductionmentioning

confidence: 99%

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Comparison of postoperative analgesic efficacy of preemptive USG-guided TAP block, USG-guided local infiltration and intravenous dexketoprofen in inguinal hernia repair

Salık

Bıçak

Akelma

2020

Preprint

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Background Although regional techniques have been suggested more in order to provide postoperative analgesia in inguinal hernia repairs, the ideal method is still controversial. The aim of this study was to evaluate the effect of preemptive transversus abdominis plane (TAP) block, local anesthetic infiltration (LAI) and intravenous dexketoprofen (IVD) on postoperative pain in inguinal hernia repairs. Methods This prospective study included 120 patients with American Society of Anesthesiologists status 1-3 between 18-75 years of age who undergoing elective inguinal hernia surgery under spinal anesthesia. The patients were allocated into three groups: USG-guided TAP block (Group 1, n = 40), USG-guided LAI (Group 2, n = 40) and IVD (Group 3, n = 40) before surgical incision. The mean of tramadol consumption, number of patients in requiring rescue analgesics, duration of postoperative analgesia and complications were recorded for 24 hours postoperatively. VAS scores were evaluated at the 30 minute, 1, 2, 4, 8, 12, 16 and 24th hours. Results There was no significant difference between the postoperative mean tramadol consumption [Group 1: 22.5 mg; Group 2: 20 mg; Group 3: 27.5 (p 0.833)]. The number of patients requiring rescue analgesics was statistically similar (p 0.787). VAS scores at 30. min, 1, 2, 4, 8 and 12 hours were statistically lower in Group 1 than in the other groups (p 0.003, 007, 0013, 0049, 0015, 0021). VAS scores at 30. min and 2. h were lower in Group 1 than Group 2 (p 0.049, 0.037). İn addition, VAS scores at 30 min, 1, 2, 8 and 12 hours were lower in Group 1 than in Group 3 (p 0.003, 0.006, 0.021, 0.017, 0.016). VAS scores at all hours were statistically similar between Group 2 and Group 3. Conclusion This study demonsrated that preemptive transversus abdominis plane block, local anesthetic infiltration or iv dexketoprofen for postoperative analgesia in inguinal hernia repairs had similar effects on postoperative tramadol consumption and number of requiring rescue analgesic patients. However, TAP block provides lower VAS values and excellent analgesia in more patients in the first 24 hours postoperatively.

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Section: Introductionmentioning

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Comparison of postoperative analgesic efficacy of preemptive USG-guided TAP block, USG-guided local infiltration and intravenous dexketoprofen in inguinal hernia repair

Salık

Bıçak

Akelma

2020

Preprint

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“…It may include NSAIDs, COX-2 inhibitors, pregabalin, gabapentin, and acetaminophen. The medications are administered 1 to 2 hours before incision (7) . Preemptive analgesia is an important part of multimodal analgesia (5).…”

Section: Introductionmentioning

confidence: 99%

Gabapentin plus celecoxib as preemptive analgesia in complex spine surgery for improving perioperative patient anxiety and satisfaction, Is it effective? randomized double- blind controlled clinical trial

Roushdy

Gadelrub²,

Abdo³

2022

Minia Journal of Medical Research

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“…Bu iki uygulamanın dışında intravenöz analjezik ilaç(İVAİ) uygulaması da çoğu klinikte farmakolojik postoperatif analjezi yöntemi olarak kullanılmaktadır 1,11 . Bu amaçla nonsteroid antiinflamatuar ilaçlar (nsaii), parasetamol, siklooksijenaz inhibitörleri, opioidler, glukokortikoidler, klonidin, magnezyum, gabapentin ve pregabalin gibi çeşitli ilaçlar kullanılmaktadır 1,11,12 . Bu ilaçlardan biri olan deksketoprofen farklı cerrahi işlemlerde postoperatif analjezi sağlamak için kullanılmıştır 13 .…”

Section: Introductionunclassified

“…İnguinal herni operasyonlarında her üç yöntemin de preemptif olarak kullanıldığı birçok çalışma mevcuttur 1,12…”

Section: Introductionunclassified

İnguinal herni onarımında USG eşliğinde TAP blok, USG eşliğinde yara yeri infiltrasyonu ve intravenöz deksketoprofenin preemptif uygulanmasının postoperatif analjezik etkinliklerinin karşılaştırılması

Salık

2021

Dicle Tıp Dergisi

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İnguinal herni onarımlarında ideal postoperatif analjezi yöntemi halen tartışma konusudur. Bu çalışmada, kasık fıtığı onarımlarında preemptif olarak uyguladığımız farklı analjezik yöntemlerin postoperatif analjezik etkinliğini karşılaştırmayı amaçladık.Yöntemler: Bu çalışma prospektif olarak dizayn edildi. Çalışmaya spinal anestezi eşliğinde elektif inguinal herni onarımı yapılan 18-75 yaş arası hastalar alındı. 120 hasta cerrahi insizyondan önce uygulanan analjezik yönteme göre üç gruba ayrıldı. Grup 1: USG kılavuzluğunda Transversus abdominis plan bloğu (n = 40), Grup 2: USG kılavuzluğunda lokal anestezik infiltrasyon (n = 40) ve Grup 3 intravenöz deksketoprofen (n = 40). Postoperatif 24 saat boyunca ortalama tramadol tüketim miktarı ve kurtarıcı analjezik ihtiyacı olan hasta sayısı kaydedildi.

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Preemptive Analgesia, Regional Anesthesia, and Prevention of Chronic Postoperative Pain

Cited by 6 publications

References 118 publications

Comparison of postoperative analgesic efficacy of preemptive USG-guided TAP block, USG-guided local infiltration and intravenous dexketoprofen in inguinal hernia repair

Comparison of postoperative analgesic efficacy of preemptive USG-guided TAP block, USG-guided local infiltration and intravenous dexketoprofen in inguinal hernia repair

Gabapentin plus celecoxib as preemptive analgesia in complex spine surgery for improving perioperative patient anxiety and satisfaction, Is it effective? randomized double- blind controlled clinical trial

İnguinal herni onarımında USG eşliğinde TAP blok, USG eşliğinde yara yeri infiltrasyonu ve intravenöz deksketoprofenin preemptif uygulanmasının postoperatif analjezik etkinliklerinin karşılaştırılması

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