Preferential concentration of particles in a fully developed turbulent square duct flow

Winkler, Chad; Rani, Sarma L.; Vanka, Surya Pratap

doi:10.1016/j.ijmultiphaseflow.2003.11.003

Cited by 52 publications

(36 citation statements)

References 31 publications

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“…The time-averaged mean velocity plots in channel centre (Figure 4 and Figure 5 ) show reasonably good agreement with the numerical results published by Winkler et al [10] and Huser and Biringen [4]. Note the non dimensional velocity in channel centre is proportional to Reynolds number.…”

Section: Discussionsupporting

confidence: 86%

“…The profiles of the root mean square velocities in Figure 4 match the data of Winkler et al [10]. The slope of u rms corresponds to the slope of Winkler's data at a downstream position of x = 3d.…”

Section: Formation Of the Velocity Fieldsupporting

confidence: 76%

“…The SLG 270 is driven by a N 2 gas flux of about dV/dt = 150 l/h, which is a contribution to the overall volume flux in the test section of approximately 1%. However, the time-averaged mean velocity profiles seem to approach the slope of LES data published by Winkler et al [10]. It is assumed that this approach might be approximately finished after 20 hydraulic diameters further downstream.…”

Section: Formation Of the Velocity Fieldmentioning

confidence: 60%

“…The maximum of u rms (x = 3d) in the nearwall region is nicely reproduced. Further downstream the magnitude of u rms overshoots the level of Winkler (Winkler et al [10]), which might be an effect of higher wall roughness and surface irregularities of the experimental facility.…”

Section: Formation Of the Velocity Fieldmentioning

confidence: 96%

“…Recently, Winkler et al [10] performed a Large Eddy Simulation (LES) of a turbulent square duct flow at Reynolds numbers of 360 based on the friction velocity. It is shown that aerosol particles tend to accumulate in regions of low vorticity magnitude.…”

Section: Introductionmentioning

confidence: 99%

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PIV measurements on the formation of the flow field and aerosol particle distribution in a turbulent square duct flow

Barth¹,

Banowski²,

Hampel³

2012

Advances in Fluid Mechanics IX

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The formation of the flow field and spatial aerosol particle distribution play an important role in various industrial applications. Regarding experiments on aerosol particle transport phenomena in turbulent flows it is of essential interest to generate a homogeneously mixed air stream. Particle Image Velocimetry (PIV) measurements have been conducted in order to characterize the turbulent mixing process in a small-scale gas/aerosol test facility which is designed for the investigation of deposition and resuspension of nuclear aerosol particles. The turbulent flow field in a square duct (Re d = 8.9k..43k) is seeded with DEHS droplets in the size range of approximately d Paero = 2 µm. Firstly, the downstream formation of particle mixing is quantified in terms of the spatial distribution of the scatter light intensity of the PIV images. It is found that sufficient mixing of the aerosol particles is accomplished at 8 to 10 hydraulic diameters downstream of the injection point. Furthermore, the formation of the flow field is evaluated in terms of the time mean averaged velocity as well as velocity fluctuations. These values are presented at successive downstream positions and display the development of the turbulent boundary layer. It is shown that the near wall turbulent region of the test section nicely follows the universal slope of a well developed turbulent boundary layer. Nevertheless, the flow field formation still takes place after 20 hydraulic diameters.

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Section: Discussionsupporting

confidence: 86%

Section: Formation Of the Velocity Fieldsupporting

confidence: 76%

Section: Formation Of the Velocity Fieldmentioning

confidence: 60%

Section: Formation Of the Velocity Fieldmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

PIV measurements on the formation of the flow field and aerosol particle distribution in a turbulent square duct flow

Barth¹,

Banowski²,

Hampel³

2012

Advances in Fluid Mechanics IX

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Mechanisms of particle dispersion in a turbulent, square duct flow

Fairweather¹,

Ye²

2009

AIChE Journal

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Particle dispersion in a square duct flow is studied using large eddy simulation combined with Lagrangian particle tracking under conditions of one-way coupling. The flow has a bulk Re ¼ 250 k, with six particle sizes ranging from 5 to 1000 lm. Results obtained for the fluid phase show good agreement with experimental data. For particles, predictions demonstrate that secondary flows within the duct dominate small particle dispersion and result in a uniform distribution, whereas gravity promotes the deposition of large particles on the duct floor. For the largest particles, the secondary flows contribute to particle concentration in corners on the duct floor, with these particles also clustering in low-velocity regions close to the floor. A detailed analysis of the influence of the flow on particle distribution is provided through consideration of the particle dispersion function, with the mechanisms of particle dispersion elucidated using a dynamical analysis.

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Secondary anchor targeted cell release

Ansari¹,

Lee-Montiel²,

Amos

et al. 2015

Biotech & Bioengineering

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Personalized medicine offers the promise of tailoring therapy to patients, based on their cellular biomarkers. To achieve this goal, cellular profiling systems are needed that can quickly and efficiently isolate specific cell types without disrupting cellular biomarkers. Here we describe the development of a unique platform that facilitates gentle cell capture via a secondary, surface-anchoring moiety, and cell release. The cellular capture system consists of a glass surface functionalized with APTES, d-desthiobiotin, and streptavidin. Biotinylated mCD11b and hIgG antibodies are used to capture mouse macrophages (RAW 264.7) and human breast cancer (MCF7-GFP) cell lines, respectively. The surface functionalization is optimized by altering assay components, such as streptavidin, d-desthiobiotin, and APTES, to achieve cell capture on 80% of the functionalized surface and cell release upon biotin treatment. We also demonstrate an ability to capture 50% of target cells within a dual-cell mixture. This engineering advancement is a critical step towards achieving cell isolation platforms for personalized medicine.

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Preferential concentration of particles in a fully developed turbulent square duct flow

Cited by 52 publications

References 31 publications

PIV measurements on the formation of the flow field and aerosol particle distribution in a turbulent square duct flow

PIV measurements on the formation of the flow field and aerosol particle distribution in a turbulent square duct flow

Mechanisms of particle dispersion in a turbulent, square duct flow

Secondary anchor targeted cell release

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