Pregnancy after Bariatric Surgery: Obstetric and Perinatal Outcomes and the Growth and Development of Children

Dell’Agnolo, Cátia Millene; Cyr, Caroline; Montigny, Francine de; Carvalho, Maria Dalva de Barros; Pelloso, Sandra Marisa

doi:10.1007/s11695-015-1668-9

Cited by 22 publications

(15 citation statements)

References 61 publications

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“…On the contrary, a reduced weight gain is associated with prematurity and low birthweight. Pregnant women who present an insufficient weight increase should be subject to more frequent monitoring of fetal growth . In this study, 15 out of 34 (44.1%) pregnant women presented a weight gain that was higher than that recommended.…”

Section: Discussionmentioning

confidence: 79%

“…As with GDM, most studies report that pregnant women who have had BS have a lower risk of developing pre‐eclampsia when compared to obese women not undergoing BS . There is also a reference to a reduced risk of developing eclampsia, gestational hypertension, and complications related to chronic hypertension . A meta‐analysis revealed that in pregnant women post‐BS, there is a 50% reduction in the risk of developing GDM or hypertensive problems when compared to a non‐BS obese control group .…”

Section: Discussionmentioning

confidence: 99%

“…Currently the most frequently performed procedure is RYGB . Most surgeries are performed on women of reproductive age, and therefore pregnancy after BS is becoming an increasingly frequent challenge for the multidisciplinary teams that follow‐up on these pregnant women …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Pregnancy after bariatric surgery: Maternal and fetal outcomes of 39 pregnancies and a literature review

Costa

Belo

Souteiro

et al. 2018

J of Obstet and Gynaecol

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Section: Discussionmentioning

confidence: 79%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Pregnancy after bariatric surgery: Maternal and fetal outcomes of 39 pregnancies and a literature review

Costa

Belo

Souteiro

et al. 2018

J of Obstet and Gynaecol

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“…Intrauterine growth restriction (IUGR) is increased by 2-3 fold after bariatric surgery (15, 38). In addition, pregnancies in women who had undergone procedures such as Roux-en-Y gastric bypass or RYGB, had a greater risk for SGA in comparison to weight loss procedures that such as LAPBAND, including VSG (11).…”

Section: Discussionmentioning

confidence: 99%

Rodent vertical sleeve gastrectomy alters maternal immune health and fetoplacental development

et al. 2018

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Bariatric surgery is increasingly employed to improve fertility and reduce obesity related co-morbidities in obese women. Surgical weight loss not only improves the chance of conception but reduces the risk of pregnancy complications including pre-eclampsia, gestational diabetes, and macrosomia. However, bariatric procedures increase the incidence of intrauterine growth restriction (IUGR), fetal demise, thromboembolism and other gestational disorders. Using our rodent model of vertical sleeve gastrectomy (VSG), we tested the hypothesis that VSG in diet-induced, obese dams would cause immune and placental structural abnormalities that may be responsible for fetal demise during pregnancy. VSG dams studied on gestational day (G) 19 had reduced circulating T cell (CD3+ and CD8+) populations compared to lean or obese controls. Further, local interleukin 1 β and interleukin 1 receptor antagonist mRNA were increased in placenta of VSG dams. Placental barrier function was also affected, with increased trans-placental permeability to small molecules, increased matrix metalloproteinase 9 expression, and increased apoptosis in VSG. Furthermore, we identified increased placental mTOR signaling that may contribute to preserving the body weight of the fetuses during gestation. These changes occurred in the absence of a macronutrient deficit or gestational hypertension in the VSG dams. In summary, previous VSG in dams may contribute to fetal demise by affecting maternal immune system activity and compromise placental integrity.

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“…Studies reported decreased risk of GHT and pre‐eclampsia in women who had undergone bariatric surgery when compared with obese pregnant women . In a meta‐analysis, Yi et al .…”

Section: Discussionmentioning

confidence: 99%

Effects of laparoscopic sleeve gastrectomy on obstetric outcomes within 12 months after surgery

Karadağ

Demircan

Çalışkan

2019

J of Obstet and Gynaecol

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Aim: To determine the obstetric and neonatal outcomes of pregnant patients having undergone laparoscopic sleeve gastrectomy (LSG) in the previous 12 months. Methods: This retrospective and observational study included 144 pregnant women: 48 had pregnancies within 12 months after LSG (Group A), 42 became pregnant more than 1 year after surgery (Group B) and 54 obese pregnant women who had a body mass index (BMI) >30 kg/m 2 , were categorized as the control group because they did not undergo surgery (Group C). The participants' early gestational BMI, predelivery BMI and gestational weight gain were determined and the obstetric and neonatal outcomes of the groups were compared. Results: The time interval from surgery to conception was 7.8 AE 3.4 months and 25.8 AE 13.4 months for Groups A and B, respectively (P < 0.01). There were no significant differences in the rates of gestational hypertension, pre-eclampsia, preterm delivery and cesarean section between the groups. The number of patients with gestational diabetes mellitus was significantly higher in Group C than in Groups A and B (P = 0.004). The number of large-for-gestational-age infants was higher in Group C than in Groups A and B (P = 0.046). The number of small-for-gestational-age infants was significantly higher in Group A than in Groups B and C (P = 0.025). Conclusion: Pregnancy within one year after LSG is related to an increased risk of small-for-gestational-age infants. LSG decreases the risk of gestational diabetes mellitus independent of the time interval between surgery and conception.

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Pregnancy after Bariatric Surgery: Obstetric and Perinatal Outcomes and the Growth and Development of Children

Cited by 22 publications

References 61 publications

Pregnancy after bariatric surgery: Maternal and fetal outcomes of 39 pregnancies and a literature review

Pregnancy after bariatric surgery: Maternal and fetal outcomes of 39 pregnancies and a literature review

Rodent vertical sleeve gastrectomy alters maternal immune health and fetoplacental development

Effects of laparoscopic sleeve gastrectomy on obstetric outcomes within 12 months after surgery

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