Pregnancy After Transfer of Sperm Under Zona

Ng, Soon-Chye; Bongso, Ariff; Ratnam, S. S.; Sathananthan, Henry; Chan, ClementL.K.; Wong, P. C.; Hägglund, Leif; Anandakumar, C.; Wong, YC; Goh, VictorH.H.

doi:10.1016/s0140-6736(88)92433-6

Cited by 197 publications

(53 citation statements)

References 2 publications

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“…This technique led to the birth of live offspring in the mouse [3] and human [4], but the incidence of monospermic fertilization was not high as expected, demonstrating again the limitations of SUZI.…”

Section: Introductionmentioning

confidence: 72%

“…This specific technique of SUZI evolved from animal studies that demonstrated that fertilization and development to birth of healthy live young [3] was possible. Fertilization of human oocytes [24][25][26] and human pregnancies [4] and live births [27] stimulated an increase in the clinical use of this procedure for patients who had failed to achieve fertilization in vitro and for patients with too few (or only immotile) spermatozoa to even attempt in vitro fertilization [28,29]. Pavasuthipaisit et al [30] compared fertilization and embryo development in cattle after SUZI and ICSI, and obtained a higher fertilization with ICSI, although the embryonic development to the hatched blastocyst stage was similar in both groups.…”

Section: Subzonal Sperm Insertion (Suzi)mentioning

confidence: 99%

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Current Status and Future of Micromanipulation-Assisted Fertilization in Animals and Human.

Goto

1997

Journal of Reproduction and Development

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Section: Introductionmentioning

confidence: 72%

Section: Subzonal Sperm Insertion (Suzi)mentioning

confidence: 99%

Current Status and Future of Micromanipulation-Assisted Fertilization in Animals and Human.

Goto

1997

Journal of Reproduction and Development

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“…The limitations of PZD gave rise to another micromanipulation technique called subzonal insemination (SUZI) (Ng et al 1988). In this technique (Fig.…”

Section: Assisted Fertilizationmentioning

confidence: 99%

“…In this technique (Fig. 1, Panel A), up to 3 spermatozoa were brought with an injection pipette through the ZP and deposited into the perivitelline space of a metaphase-II oocyte (Ng et al 1988, Palermo & Van Steirteghem 1991. The initial results of SUZI were encouraging.…”

Section: Assisted Fertilizationmentioning

confidence: 99%

The pioneering of intracytoplasmic sperm injection: historical perspectives

Rosenwaks

Pereira

2017

Reproduction

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Intracytoplasmic sperm injection (ICSI) has often been heralded as a ground-breaking technique that has transformed the treatment of couples with infertility. By injecting a single spermatozoon into the cytoplasm of the oocyte, ICSI bypasses the zona pellucida and increases the chances of fertilization and subsequent embryo development, independent of semen parameters. Ever since the first live births using ICSI were reported in 1992, ICSI has become the mainstay of treating male factor infertility as well as overcoming fertilization failure associated with conventional in vitro insemination. Today, ICSI is utilized in nearly 66% of all assisted reproductive treatments worldwide and has resulted in the birth of millions of babies. The primary goal of this review is to provide historical perspectives about the pioneering of ICSI. We begin by highlighting the scientific work of early investigators who elucidated the mechanisms central to mammalian fertilization. Furthermore, we briefly discuss how these findings contributed to the development of IVF for the treatment of infertility. We then emphasize the shortcomings of IVF in treating severe forms of male factor infertility and enumerate the micromanipulation techniques that were developed to circumvent these shortcomings. Finally, we indicate how the inadequacies of these micromanipulation techniques lead to the inception, application and popularity of ICSI.Reproduction (2017) 154 F71-F77

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“…Accordi ngl y, several approaches have been devel oped to assi st fertilization by ZP micromanipulation: partial zona di ssecti on (PZD), 12 sub-zonal sperm i nserti on (SUZI), 13 and i ntracytopl asmi c sperm i njecti on (ICSI).…”

Section: Introductionmentioning

confidence: 99%

Assisted reproductive technologies and monozygous twins: implications for future study and clinical practice

2000

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That the zona pel l uci da (ZP) pl ays a pr omi nent r ol e i n the physi ol ogy of some human tw i nni ng i s an attr acti ve, al bei t i ncompl etel y pr oven, medi cal hypothesi s. I ndeed, an associ ati on has been pr oposed betw een mani pul ati on of the ZP and/or nati ve ZP mi cr oar chi tectur e and monozygoti c (M Z) tw i ns. Ovul ati on i nducti on al so has been theor eti cal l y l i nk ed to i n vi vo ZP al ter ati ons facilitating MZ twin development. In vitro fertilization (IVF) relies on necessar y (and, i n some cases extended) embr yo cul tur e techni ques potenti al l y cr eati ng subtl e ZP changes and subsequent M Z tw i nni ng. Wi th gr ow i ng exper i ence i n the assi sted r epr oducti ve technol ogi es and par ti cul ar l y I VF, some pr el i mi nar y r epor ts have noted an i ncr eased fr equency of M Z tw i ns after pr ocedur es that ar ti fi ci al l y br each the ZP (i .e., i ntr acytopl asmi c sper m i njecti on [I CSI ], or 'assi sted hatchi ng'). Such ZP mani pul ati ons ostensi bl y enhance oocyte fer tilization or facilitate blastocyst hatching, thus i mpr ovi ng pr egnancy r ates for coupl es under goi ng fer tility treatment. Evidence exists both to chal l enge and suppor t the connecti on betw een these phenomena and M Z tw i ns. Thi s r epor t outl i nes the fundamental embr yol ogi cal pr ocesses bel i eved r esponsi bl e for these confl i cti ng obser vati ons; the cur r ent l i ter atur e on the subject of human ZP mi cr o-mani pul ati on and M Z tw i ns i s al so di scussed. Twin Research (2000) 3, 217-223.

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Pregnancy After Transfer of Sperm Under Zona

Cited by 197 publications

References 2 publications

Current Status and Future of Micromanipulation-Assisted Fertilization in Animals and Human.

Current Status and Future of Micromanipulation-Assisted Fertilization in Animals and Human.

The pioneering of intracytoplasmic sperm injection: historical perspectives

Assisted reproductive technologies and monozygous twins: implications for future study and clinical practice

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