Pregnancy and birth rates after oocyte donation

Comparison of pregnancy outcomes in anonymous shared versus exclusive donor oocyte in vitro fertilization cycles

“…In 2004, fresh IVF cycles using autologous oocytes (72,406 cycles), the delivery rate per retrieval was 29.9%, whereas in fresh OD-IVF cycles (7,581 cycles), the delivery rate per transfer was 43.7% (18). Higher success rates in OD cycles are attributed to the improvement in oocyte quality in comparison to the heterogeneous group of women undergoing standard IVF/ICSI cycles (2,19).…”

Oxygen consumption is a quality marker for human oocyte competence conditioned by ovarian stimulation regimens

“…Serum E 2 and P levels were measured on the morning of hCG administration. The protocol for endometrial preparation of recipients can be found elsewhere (34)(35)(36)(37). In brief, patients with ovarian function were desensitized with a single IM administration of triptorelin 3.75 mg depot between days 18 and 21 of the previous cycle.…”

Endometrial receptivity after oocyte donation in recipients with a history of chemotherapy and/or radiotherapy

“…Sauer et al (1994) reported greater pregnancy losses after prior exposure to chemotherapy (n ¼ 8); Pados et al (1992) reported the lowest pregnancy rate after chemotherapy and/or radiotherapy (n ¼ 11) (9%). One study investigating pregnancy and birth rates after OD found no influence of the cause of entering the OD programme but only two patients enrolling had a history of cancer treatment (Remohi et al, 1997).…”

“…Patients on standby received up to 6 mg estradiol valerate a day and the duration of the treatment varied in accordance with the availability of a phenotype-matched donor, ranging from 13 to 51 days. Endometrial thickness was not routinely measured before embryo replacement (Remohi et al, 1997;Soares et al, 2005). From the day of oocyte retrieval, 800 mg of micronized progesterone (Utrogestanw, Laboratorio Seid, Barcelona, Spain) was administered vaginally.…”

“…However, only very few data based on case reports are available in the literature on the outcome of OD cycles in this particular subgroup of oocyte recipients. Most published reports show that OD is feasible but is associated with a lower pregnancy rate than that expected in the general population of oocyte recipients (Pados et al, 1992;Sauer et al, 1994;Remohi et al, 1997;Anselmo et al, 2001;Kavic et al, 2001). However, two other reports, also based on a limited number of patients, showed no difference in pregnancy rate in cancer survivors (Paulson et al, 1997;Moomjy et al, 1999).…”