Pregnancy outcome in gestational diabetes

Fan, Zitian; Yang, Huixia; Gao, Xuyuan; Lintu, H.; Sun, Wen

doi:10.1016/j.ijgo.2006.03.021

Cited by 41 publications

(39 citation statements)

References 20 publications

(21 reference statements)

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“…Diabetes can cause endothelial dysfunction (Calles-Escandon and Cipolla 2001; Dandona et al 2006), which may contribute to the pathophysiology of PE (Lyell et al 2003; Roberts and Lain 2002; Salas 1999), as supported by studies showing that tight glycemic control reduces the risk of PE in women who had diabetes before becoming pregnant (Crowther et al 2005; Fan et al 2006; Yogev et al 2004). Another study also showed that increasing glucose intolerance among nondiabetics is also associated with PE (Sermer et al 1995).…”

Section: Discussionmentioning

confidence: 95%

Pesticide Exposure and Hypertensive Disorders During Pregnancy

Saldana

Basso²,

Baird³

et al. 2009

Environ Health Perspect

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BackgroundHypertensive disorders of pregnancy, including pregnancy-induced hypertension (PIH) and preeclampsia (PE), complicate 2–8% of pregnancies. Few studies have examined environmental risk factors in relation to these conditions.ObjectivesOur goal was to examine whether pesticide exposure during pregnancy was associated with hypertensive disorders of pregnancy.MethodsWe analyzed self-reported data from 11,274 wives of farmers enrolled in the Agricultural Health Study (AHS) between 1993 and 1997. Using logistic regression models, we estimated the adjusted odds ratios (AORs) for PIH and PE associated with pesticide-related activities during the first trimester of pregnancy.ResultsFirst-trimester residential and agricultural activities with potential exposure to pesticides were associated with both PIH [residential AOR = 1.27; 95% confidence interval (CI), 1.02–1.60; agricultural AOR = 1.60; 95% CI, 1.05–2.45] and PE (residential AOR = 1.32; 95% CI, 1.02–1.70; agricultural AOR = 2.07; 95% CI, 1.34–3.21).ConclusionsExposure to pesticides during pregnancy may increase the risk of hypertensive disorders of pregnancy. Laboratory research may provide insights into relationships between pesticide exposure and hypertensive diseases of pregnancy.

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Section: Discussionmentioning

confidence: 95%

Pesticide Exposure and Hypertensive Disorders During Pregnancy

Saldana

Basso²,

Baird³

et al. 2009

Environ Health Perspect

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“…It would seem that the prevention of macrosomia should be the primary goal of GD management. Several studies suggest an increased rate of preeclampsia among women with GD, and a combination of maternal diabetes and pre-eclampsia is associated with poor perinatal outcome (Fan et al, 2006). Untreated or poorly controlled gestational diabetes can hurt the baby.…”

Section: Risk Factors For Gdmentioning

confidence: 99%

“…In recent years there has been a reported increased trend in the prevalence of GD throughout the world, with huge health-care and economic costs (Bellamy et al, 2009). This is particularly the case in developed countries, such as the USA, the UK, Australia, China and New Zealand (Sinha et al, 2003;Ferrara et al, 2004;Joshy & Simmons, 2006;Metzger & Counstan, 1998;Fan et al, 2006;Carolan et al, 2010). The increased prevalence has been recently disputed, suggesting that more cases were identified through more aggressive universal screening.…”

Section: Prevalence Of Gdmentioning

confidence: 99%

Prevalence and Risk Factors for the Development of GD in Some Eastern European Countries – Tendencies and Pharmacoeconomical Assessment for the Choice of Treatment

Petkova¹,

Nikolova²

2011

Gestational Diabetes

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“…Respecto a la morbilidad metabólica (hipocalcemia e hipomagnesemia e hiperbilirrubinemia), esta se presentó en un bajo porcentaje en este estudio, comparándose con lo reportado en la literatura mundial, ya que se muestra hasta en un 40% y 30% respectivamente (18). La información en relación a la baja frecuencia de ambas patologías metabólicas neonatales, habría que tomarla con reserva debido a que en el hospital donde se realizó el estudio no es común la búsqueda de hipomagnesemia y, por otro lado, los datos clínicos son semejantes a los de hipocalcemia.…”

Section: Tabla II Morbilidad Neonatal Asociada a La Diabetes Gestacionalunclassified

Morbilidad Y Mortalidad Neonatal Asociada a La Diabetes Gestacional

M³

2010

Rev. chil. obstet. ginecol.

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RESUMENObjetivo: Determinar la asociación de la morbilidad y mortalidad neonatal con la diabetes gestacional. Método: Estudio tipo cohortes. Se realizó un estudio en embarazadas desde diciembre de 2007 a noviembre de 2008 en el servicio de tococirugía del Hospital General Regional No. 1 de Querétaro, México, se formaron dos grupos de 71 pacientes, uno con diabetes gestacional y otro sin ella. El muestreo fue por cuota pareado por edad. En ambos grupos se midieron variables sociodemográficas, antecedentes obstétricos, vía de interrupción del embarazo, morbilidad y mortalidad neonatal. Los resultados se analizaron con Chi cuadrado y riesgo relativo con un poder alfa de 0,05. Resultados: La tasa de morbilidad en el grupo expuesto fue de 60%. Las variables que tuvieron significancia estadística fueron: la obesidad pregestacional (RR: 2,7), cesárea (RR: 3,3), complicaciones metabólicas (RR: 10), morbilidad respiratoria (RR: 6,7), macrosomía (RR: 4,1), hipoglucemia (RR: 14,2) y taquipnea transitoria del recién nacido (RR: 7,7). La edad materna, sobrepeso gestacional, nivel socioeconómico, escolaridad, antecedentes de macrosómicos, de cesáreas y de malformaciones congénitas; malformaciones congénitas, bajo peso neonatal, prematurez, enfermedad de membrana hialina, hiperbilirrubinemia, hipocalcemia, mortalidad neonatal y la asfixia no tuvieron asociación significativa. La complicación metabólica más frecuente fue: hipoglucemia (17,2%). No hubo muertes perinatales. Conclusiones: El grupo expuesto estudiado mostró mayor morbilidad asociada a la diabetes gestacional que el grupo no expuesto, es necesario el diagnóstico temprano en mujeres con factores de riesgo para esta entidad y establecer un programa de tratamiento con vigilancia estrecha. PALABRAS CLAVE: Diabetes gestacional, morbilidad neonatal, mortalidad neonatal, riesgo perinatal SUMMARY Objectives:To determine the association of neonatal morbidity and mortality with gestational diabetes. Methods: Study cohort. A study of pregnant women from December 2007 to November 2008 in the service of ginecology and obstetrics HGR No. 1 Queretaro, were divided into two groups of 71 patients, one gestational diabetic and one without it. The quota sampling was matched by age. In both groups were measured sociodemographic, obstetric history, via interruption of birth, neonatal morbidity and mortality. The results were analyzed with Chi square and relative risk with a power alpha of 0.05. Results: The morbidity rate in the exposed group was 60%. Variables that were statistically significant were: pregestational obesity (RR: 2.7), cesarean (RR 3.3), metabolic complications (RR 10), respiratory illness (RR: 6.7), macrosomia (RR: 4.1), hypoglycemia (RR: 14.2) and transient tachypnea of the newborn (RR: 7.7). Maternal age, gestational overweight, socioeconomic status, education, history of macrosomic, and cesarean birth defects, REV CHIL OBSTET GINECOL 2010; 75(1): 35 -41

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Pregnancy outcome in gestational diabetes

Abstract: Aggressive management for tight glycemic control improves maternal and neonatal outcomes in women with GDM.

Cited by 41 publications

References 20 publications

Pesticide Exposure and Hypertensive Disorders During Pregnancy

Pesticide Exposure and Hypertensive Disorders During Pregnancy

Prevalence and Risk Factors for the Development of GD in Some Eastern European Countries – Tendencies and Pharmacoeconomical Assessment for the Choice of Treatment

Morbilidad Y Mortalidad Neonatal Asociada a La Diabetes Gestacional

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