Pregnancy outcomes after endometrial receptivity array in an infertile population

Abstract

or live birth rates compared with non-injury to the endometrium. Furthermore, endometrial injury in the proliferation phase results in the same effects on the clinical outcomes as the luteal phase. References: 1. Relji M, Knez J, Kova V, Kova B. Endometrial injury, the quality of embryos, and blastocyst transfer are the most important prognostic factors for in vitro fertilization success after previous repeated unsuccessful attempts.

Retraction notice to ‘The impact of an endometrial receptivity array on personalizing embryo transfer for patients with infertility: a meta-analysis’ [F&S Reviews 3 (2022) 157-173]

“…The detailed characteristics of the included studies, such as the study design, country, year, patient characteristic, sample size, mean age, and primary outcome, are shown in Table 1 (26)(27)(28)(29)(30)(31)(32)(33). In general, the 17 studies (4 RCTs and 13 cohort studies) included data from 7,052 patients who underwent PET and standard embryo transfer (SET).…”

“…However, the remaining 2 RCTs still had a high risk of bias because of the incomplete data outcomes and lack of selective reporting (16,27). Figure 6 shows the bias assessment score of the 13 cohort studies (9,10,12,17,19,22,23,28,29,(31)(32)(33). Overall, no study reached the maximum score.…”

“…The lowest-quality study (45%) had problems in providing variables, data source, bias, and study size (28). Additionally, 5 studies did not provide sufficient discussion for interpreting their findings (28)(29)(30)(31)(32). The limitations were not fully investigated in 7 studies (9,23,(28)(29)(30)(31)(32).…”

Endometrial Dating Method Detects Individual Maturation Sequences During the Secretory Phase

“…Molecular methods simultaneously analyzing hundreds of genes appeared likely at one time to become the new standard, offering new ways of predicting the implantation window (1). In addition to the high cost of the endometrial receptivity array and its complexity, however, further studies showed that performing this test in a mock cycle before an embryo transfer did not improve the ongoing pregnancy rate in patients who had a good prognosis (2,3).…”

Effectiveness comparison between endometrial receptivity array, immune profiling and the combination in treating patients with multiple implantation failure

“…7,10,11 However, the standpoint of ERA effectiveness in clinical practice is contradictory. [12][13][14] Displaced and pathological windows of implantation can contribute independently or collectively to implantation failure, 15 which might explain the contradictory results of ERA in clinical practice.…”