Preliminary investigation on ultra high diluted B. vulgaris in experimental urolithiasis

Jyothilakshmi, Vasavan; Thellamudhu, Ganesan; Kumar, Alok; Khurana, Anil; Nayak, Debadatta; Kalaiselvi, Periandavan

doi:10.1016/j.homp.2013.05.004

Cited by 13 publications

(4 citation statements)

References 30 publications

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“…Anti-diabetic activity: B. vulgaris : Rajaei et al, 2011[ 103 ]; Meliani et al, 2011[ 85 ]. Urolithiasis: B. vulgaris : Jyothilakshmi et al, 2013[ 65 ]; Bashir and Gilani, 2011[ 10 ]. Osteolytic and Hyper choletrolemic: B. aristata : Zhou et al, 2012[ 149 ]; Rahigude et al, 2012[ 102 ]; Dong et al, 2011[ 32 ]; Huang et al, 2012[ 51 ]).…”

Section: Pharmacological Activities Of Berberis Speciesmentioning

confidence: 99%

A review on biological and chemical diversity in Berberis (Berberidaceae)

Srivastava

Misra

et al. 2015

EXCLI Journal; 14:Doc247; ISSN 1611-2156

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Section: Pharmacological Activities Of Berberis Speciesmentioning

confidence: 99%

A review on biological and chemical diversity in Berberis (Berberidaceae)

Srivastava

Misra

et al. 2015

EXCLI Journal; 14:Doc247; ISSN 1611-2156

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“…[11][12][13][14] A homeopathic preparation of Berberis vulgaris has shown anti-urolithiasis properties in an animal model. 15 Thlaspi bursa pastoris (TBP) is commonly known as Shepherd's purse. 10 It is an annual plant that grows particularly in eastern Europe.…”

Section: Introductionmentioning

confidence: 99%

Thlaspi bursa pastoris in Treatment of Urinary Stones: A Case Series

Nayak

Sahoo

Nayak³

2020

Homeopathy

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Abstract Background Urinary stones are the most common cause of acute ureteral obstruction. The homeopathic medicine Thlaspi bursa pastoris (TBP) has many symptoms similar to the typical symptoms of urolithiasis, yet its clinical usefulness has not been well documented. Patients In this study, the clinical symptoms of each of five patients, along with ultrasonographic evidence, were taken for the assessment of the outcome. TBP was prescribed in potency 30c and/or 200c to each patient on the basis of the main symptoms, typically dysuria, retention of urine and haematuria. Each case was followed for up to 6 months. Assessment of causal attribution of treatment effect was performed using the Modified Naranjo Criteria. Results There was full recovery of all five patients and post-treatment ultrasonography showed no calculi remaining. The Modified Naranjo Criteria total score for each patient was either +8/13 or +9/13. Conclusion TBP was observed to be effective in eliminating renal stones within a short span of time and without any complications.

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“…Furthermore, the Ephedra plant material investigated in this study is richer in alkaloids (1.34%) than Ephedra alata grown in Iraq (0.2%) [30]. The radical-scavenging potential of AE was shown in Figure 3.…”

Section: Quantification Of Ephedrine Alkaloidsmentioning

confidence: 84%

"Alkaloids Isolated from Ephedra Alata: Characterization and Protective Effects Against Cisplatin-Induced Liver and Kidney Injuries in Mice"

Sioud¹,

Mangelinckx²,

Lahmer

et al. 2021

BJSTR

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Cisplatin (CP) is one of the most efficacious chemotherapeutic antitumor drugs. Oxidative stress has been proven to be involved in CP-induced toxicity. The aim of this study was designed to assess the protective effects of Ephedra alata alkaloids extract (AE) on liver and kidney injuries induced by CP. The 1H-RMN analysis of AE extract detected the presence of ephedrine, pseudoephedrine, methylephedrine and methylpseudoephedrine. To evaluate the effect of AE extract on CP-toxicity, the mice were administrated with 150 mg/kg of AE for 7 days, and the liver and kidney injury models were established by single intraperitoneal injection of CP (20mg/kg) on the fourth day. Compared with the model group, the activities of aspartate aminotransferase, alanine aminotransferase and the content of creatinine in serum all decreased in mice treated with AE extract. Meanwhile, the activities of superoxide dismutase, catalase increased, and the content of malondialdehyde and DNA damage decreased. In addition, the histopathologic aspects showed that the pathological changes of liver and kidney were found in the model group reduced after treatment with AE. Therefore, AE could reduce the damage of liver and kidney caused by CP by reducing the level of oxidative stress, and improving the antioxidant, capacity of the body.

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Preliminary investigation on ultra high diluted B. vulgaris in experimental urolithiasis

Abstract: Homeopathic B. vulgaris root bark has strong anti-urolithiasis potential at ultra-diluted dose.

Cited by 13 publications

References 30 publications

A review on biological and chemical diversity in Berberis (Berberidaceae)

A review on biological and chemical diversity in Berberis (Berberidaceae)

Thlaspi bursa pastoris in Treatment of Urinary Stones: A Case Series

"Alkaloids Isolated from Ephedra Alata: Characterization and Protective Effects Against Cisplatin-Induced Liver and Kidney Injuries in Mice"

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