Preliminary study on crystal dissolution activity of Rotula aquatica, Commiphora wightii and Boerhaavia diffusa extracts

Raut, Atul; Sunder, Sudha; Sarkar, Subrata; Pandita, Nancy; Vaidya, Ashok D.B.

doi:10.1016/j.fitote.2008.06.001

Cited by 9 publications

(4 citation statements)

References 5 publications

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“…Pharmacological studies have demonstrated that B. diffusa known to possess anticonvulsant [4] , diuretic, anti-inflammatory, antifibrinolytic [9] , antibacterial [10] , anti-hepatotoxic, anthelmintic, febrifuge, anti-leprosy, antiasthmatic, antiurethritis, antilymphoproliferative [11] , antimetastatic [12] , immunosuppressive [13] , antidiabetic, antioxidant [14] , immune-modulation [15] , hepatoprotective [16] , anti-nociceptive, nephroprotective [17] , bacteria induced ulcer & diarrhea [18] and antiurolithiatic [19] activities. The identification of phytoconstituents and assay of antioxidant, thrombolytic, cytotoxic, antimicrobial activities were conducted using specific standard in vitro procedures.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical screening and in vitro bioactivities of the extracts of aerial part of Boerhavia diffusa Linn.

Apu

Liza

Jamaluddin

et al. 2012

Asian Pacific Journal of Tropical Biomedicine

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Section: Introductionmentioning

confidence: 99%

Phytochemical screening and in vitro bioactivities of the extracts of aerial part of Boerhavia diffusa Linn.

Apu

Liza

Jamaluddin

et al. 2012

Asian Pacific Journal of Tropical Biomedicine

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“…The effect of plant was assayed on microcrystals in 24-well microplates in vitro. The results showed that the aqueous extracts of R. aquatica have crystal dissolving activity against MSUM [21] Prashanthi et al, reported, the antiurolithiatic potential of Rotula roots by a methodical approach, using simple in-vitro model. The study involved the preparation of Calcium oxalate and phosphate and its dissolution in presence of Rotula aquatica.…”

Section: Antiurolithiatic Activitymentioning

confidence: 99%

Rotula aquatica. Lour-A Review on Medicinal uses Phytochemistry and Pharmacological actions

T¹,

Remya²,

Rani³

et al. 2017

IJPBR

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Rotula aquaticLour is an important medicinal herb in Ayurvedic system of medicine. The plant occurs as a small branched shrub that grows characteristically among rocks and trailing over pebbles in stream beds, belonging to the family Boraginaceae and widely distributed throughout India. It is commonly called as Pasanabheda in Ayurveda. As only few studies are done on this plant, the comprehensive review presenting here will summarize regarding its Phytochemical and Pharmacological activities with the help of available and update information. Various studies indicated the antiurolithiatic, hypoglycemic, anti-inflammatory, antibacterial and anthelmintic properties of Rotula aquatica. Although the information are very encouraging and revealed some of the constituents of the plant like polyphenols and tannins as important therapeutically agents. The herb should be studied more extensively to confirm these results and reveal other potential therapeutic effects. Various traditional claims of the plant are still remain to be validated scientifically. Clinical trials for the reported preclinical studies should be performed urgently to further validate the claims on humans

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“…In a study conducted by Raut et al 100 on crystal dissolution activity of alcoholic and hydroalcoholic extracts of B. diffusa (500 µl) roots on crystals of monosodium urate monohydrate, calcium pyrophosphate monohydrate and basic calcium phosphate, the extracts failed to dissolute the crystals of monosodium urate monohydrate.…”

Section: Effect On Crystal Dissolutionmentioning

confidence: 99%

A review of the plant Boerhaavia diffusa: its chemistry, pharmacology and therapeutical potential

Nayak¹,

Thirunavoukkarasu²

2016

J Phytopharmacol

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Introduction: Boerhaavia diffusa, a perennial creeping weed found in tropics and sub-tropics is a well known ethno-medicinal plant. The whole plant as well as its different parts (leaves, roots and stems) and plant extracts have been widely used in various traditional and folklore systems of medicine for treatment of various ailments. A number of phytochemicals e.g. flavonoids (C-methylflavone, 5,7-dihydroxy-3’,4’-dimethoxy- 6,8- dimethylflavone, 3,5,4′- dihydroxy-6,7-dimethoxyflavone, 6’, 5’-dimethoxy-5, 7, 3-trihydroxyflavone, borhavone, 3,3’,5-trihydroxy-7-methoxyflavone, 4’,7-dihydroxy-3’-methylflavone), alkaloids (punarnavine), glycosides (punarnavoside, eupalitin 3-O-β-D-galactopyranosyl-(1’’’2’’)-O-β-D-galactopyranoside, 3,4- dimethoxyphenyl-1-O-β-D apiofuranosyl-(1’’3’)-O-β-D-glucopyranoside), rotenoids (boeravinone A-H), steroids, triterpenoids, lipids, lignans, carbohydrates, proteins, and glycoproteins etc have been reported from the herb. Several researchers have confirmed biological, pharmacological and clinical activities of the plant and its phyto-constituents. Some of the promising effects of this plant include diuretic, hepatoprotective, antiinflammatory, anti-fibrinolytic, anti-cancer, anti-diabetic, immuno-modulatory, immuno-suppressive, antilymphoproliferative, analgesic properties and used in treatment of pulmonary tuberculosis. Besides some less promising effects exhibited by this plant includes non-teratogenic, antioxidant, anti-viral activity against plant viruses, anti-bacterial, anti-fungal, adaptogenic, antiamoebic, lipotropic and anticonvulsant activity. An overview of chemical constituent of the plant, their pharmacological actions and clinical studies are summarized in the present paper.

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Preliminary study on crystal dissolution activity of Rotula aquatica, Commiphora wightii and Boerhaavia diffusa extracts

Cited by 9 publications

References 5 publications

Phytochemical screening and in vitro bioactivities of the extracts of aerial part of Boerhavia diffusa Linn.

Phytochemical screening and in vitro bioactivities of the extracts of aerial part of Boerhavia diffusa Linn.

Rotula aquatica. Lour-A Review on Medicinal uses Phytochemistry and Pharmacological actions

A review of the plant Boerhaavia diffusa: its chemistry, pharmacology and therapeutical potential

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