Two experiments investigated the relationships among degree of obesity, nearness to set point for adipose tissue mass, and responsiveness to taste. In Experiment 1, subjects rated milkshakes varying in sweetness intensity. Overweight and normal weight subjects did not have significantly different detection thresholds or preference ratings. However, overweight subjects worked longer than normals to obtain their most preferred substance. Experiment 2 varied the ease of tasting the milkshake. Preference and food intake of moderately overweight subjects were significantly more influenced by tastes that they found positive and negative than was the preference of normal weight or obese subjects. The ease of ingesting the taste substance also significantly influenced preference and food intake of the moderately obese only. Nearness to set point, operationally denned as weight stability for 2 years, had no significant effects.The association between taste responsiveness and overweight has been widely demonstrated in both animals and humans. Animals with ventromedial hypothalamic lesions typically show greater responsiveness to the sensory qualities of their food than normal weight animals without lesions (Corbit & Stellar, 1964;Teitelbaum, 1955), although finickiness and obesity can occur independently (Graff & Stellar, 1962). The eating behavior of many varieties of genetically obese mice also appears highly influenced by taste (Bray & York, 1971;Fuller & Jacoby, 1955;Rytand, 1943). Similarly, overweight humans are highly responsive to the sensory qualities of food (Hashim & Van Itallie, 1965;Nisbett, 1968Nisbett, , 1972.Although these studies demonstrate a correlation between obesity and taste responsiveness, they do not consider to which component of taste the obese are differentially reactive and precisely how this influences food intake. Experiments designed to test the first aspect of this question for humans (Grinker, in press;Grinker, Hirsch, & Smith, 1972) examined judgments