Prematurity Is the Major Risk Factor for Late‐Onset Group B Streptococcus Disease

Lin, Feng-Ying C.; Weisman, Leonard E.; Troendle, James; Adams, Karen

doi:10.1086/376457

Cited by 121 publications

(96 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This confirms that preterm delivery is the most important perinatal risk factor in late onset disease. 28 Most of the patients with very early onset GBS sepsis and very early onset probable GBS sepsis were born in hospital (85% and 87%, respectively) in contrast with about 70% of all deliveries in the Netherlands. This may be explained by the fact that in the Netherlands, pregnant women with risk factors are usually referred to hospital.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of neonatal group B streptococcal disease in the Netherlands before and after introduction of guidelines for prevention

Trijbels-Smeulders¹,

Jonge²,

Jong

et al. 2007

Archives of Disease in Childhood - Fetal and Neonatal Edition

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Epidemiology of neonatal group B streptococcal disease in the Netherlands before and after introduction of guidelines for prevention

Trijbels-Smeulders¹,

Jonge²,

Jong

et al. 2007

Archives of Disease in Childhood - Fetal and Neonatal Edition

View full text Add to dashboard Cite

“…Compared to term infants, preterm infants are much more susceptible to invasive GBS disease, in particular LONS and VLONS. In a recent case-control study of 122 infants with GBS LONS, 84% of patients were born at Ͻ34 weeks of gestation, and the risk for GBS LONS increased by a factor of 1.34 (95% CI, 1.15 to 1.56) for each week of decreasing gestation (290). This is probably due in part to low levels of maternal antibodies, which cross the placenta in the third trimester of pregnancy.…”

Section: Gram-positive Organismsmentioning

confidence: 99%

Clinical Microbiology of Bacterial and Fungal Sepsis in Very-Low-Birth-Weight Infants

2004

View full text Add to dashboard Cite

Twenty percent of very-low-birth-weight (<1500 g) preterm infants experience a serious systemic infection, and despite advances in neonatal intensive care and antimicrobials, mortality is as much as threefold higher for these infants who develop sepsis than their counterparts without sepsis during their hospitalization. Outcomes may be improved by preventative strategies, earlier and accurate diagnosis, and adjunct therapies to combat infection and protect the vulnerable preterm infant during an infection. Earlier diagnosis on the basis of factors such as abnormal heart rate characteristics may offer the ability to initiate treatment prior to the onset of clinical symptoms. Molecular and adjunctive diagnostics may also aid in diagnosing invasive infection when clinical symptoms indicate infection but no organisms are isolated in culture. Due to the high morbidity and mortality, preventative and adjunctive therapies are needed. Prophylaxis has been effective in preventing early-onset group B streptococcal sepsis and late-onset Candida sepsis. Future research in prophylaxis using active and passive immunization strategies offers prevention without the risk of resistance to antimicrobials. Identification of the differences in neonatal intensive care units with low and high infection rates and implementation of infection control measures remain paramount in each neonatal intensive care unit caring for preterm infants

show abstract

“…16 Colonisation of the mother is less predictive for late-onset GBS infection, with prematurity the major risk factor. 17 The association between the rates of maternal colonisation, transmission and infection has been established. A meta-analysis 12 of six studies of the maternal and baby colonisation rates in an untreated general population showed a transmission rate of 36.4% (95% CI 28.1-45.0%).…”

Section: Transmissionmentioning

confidence: 99%

Rapid testing for group B streptococcus during labour: a test accuracy study with evaluation of acceptability and cost-effectiveness

Daniels

Gray²,

Pattison³

et al. 2009

Health Technol Assess

View full text Add to dashboard Cite

How to obtain copies of this and other HTA programme reports An electronic version of this publication, in Adobe Acrobat format, is available for downloading free of charge for personal use from the HTA website (www.hta.ac.uk). A fully searchable CD-ROM is also available (see below).Printed copies of HTA monographs cost £20 each (post and packing free in the UK) to both public and private sector purchasers from our Despatch Agents.Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. Contact details are as follows: Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to Direct Mail Works Ltd and drawn on a bank with a UK address. Paying by credit cardThe following cards are accepted by phone, fax, post or via the website ordering pages: Delta, Eurocard, Mastercard, Solo, Switch and Visa. We advise against sending credit card details in a plain email. Paying by official purchase orderYou can post or fax these, but they must be from public bodies (i.e. NHS or universities) within the UK. We cannot at present accept purchase orders from commercial companies or from outside the UK. How do I get a copy of HTA on CD?Please use the form on the HTA website (www.hta.ac.uk/htacd.htm). Or contact Direct Mail Works (see contact details above) by email, post, fax or phone. HTA on CD is currently free of charge worldwide.The website also provides information about the HTA programme and lists the membership of the various committees. HTA NIHR Health Technology Assessment programmeT he Health Technology Assessment (HTA) programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care. The research findings from the HTA programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a key component of the 'National Knowledge Service'. The HTA programme is needs led in that it fills gaps in the evidence needed by the NHS. There are three routes to the start of projects. First is the commissioned route. Suggestions for research are actively sought from people working in t...

show abstract

Prematurity Is the Major Risk Factor for Late‐Onset Group B Streptococcus Disease

Cited by 121 publications

References 35 publications

Epidemiology of neonatal group B streptococcal disease in the Netherlands before and after introduction of guidelines for prevention

Epidemiology of neonatal group B streptococcal disease in the Netherlands before and after introduction of guidelines for prevention

Clinical Microbiology of Bacterial and Fungal Sepsis in Very-Low-Birth-Weight Infants

Rapid testing for group B streptococcus during labour: a test accuracy study with evaluation of acceptability and cost-effectiveness

Contact Info

Product

Resources

About