Premenstrual Changes and Affective Disorders1

Endicott, Jean; Halbreich, Uriel; Schacht, Sybil; Nee, John

doi:10.1097/00006842-198112000-00008

Cited by 145 publications

(43 citation statements)

References 12 publications

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“…With the exception of one study (131), the prevalence of perimenstrual symptoms is higher than expected among women with a depressive illness (1,39,(132)(133)(134). In particular, there is a higher than expected rate of premenstrual depressive syndrome among women with a lifetime diagnosis of affective illness.…”

Section: Psychiatric Historymentioning

confidence: 84%

Perimenstrual symptoms: prevalence and risk factors.

Logue¹,

Moos²

1986

Psychosomatic Medicine

180

112

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This article provides an overview of information on the prevalence of perimenstrual symptoms. Overall, at least 40% of women experience some cyclical perimenstrual symptoms. Although most women rate their symptoms as mild, approximately 2%-10% report severe symptoms. Prospective studies of perimenstrual symptoms indicate that retrospective reports are reasonably accurate among women who experience moderate to severe symptoms. However, among the majority of women with few or minimal symptoms, retrospective reports may amplify the cyclicity of variation in comparison to concurrent reports. A variety of risk factors are associated with patterns of symptom reporting and may provide clues to the etiology of perimenstrual symptoms and help to identify women most vulnerable to them. A woman's age and cycle characteristics are predictors of the type and severity of perimenstrual symptoms she experiences. In addition, a history of affective illness may be associated with increased reporting of perimenstrual symptoms. Future research should focus on developing new diagnostic criteria for subtypes of perimenstrual syndromes, exploring positive symptoms and experiences associated with the menstrual cycle, and formulating holistic treatment approaches that view perimenstrual syndromes as psychosomatic conditions.

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Section: Psychiatric Historymentioning

confidence: 84%

Perimenstrual symptoms: prevalence and risk factors.

Logue¹,

Moos²

1986

Psychosomatic Medicine

180

112

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“…Lifetime history of affective disorders was reported to be more prevalent among women with PMC [51,52]. Thus, the rather strong interactive effect of PMC and lifetime history of affective disorders on the variance of early luteal IMI binding was not surprising.…”

Section: Discussionmentioning

confidence: 99%

Imipramine Receptor Binding and Serotonin Uptake in Platelets of Women with Premenstrual Changes

Rojansky

Halbreich

Zander

et al. 1991

Gynecol Obstet Invest

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Gonadal hormones are believed to be involved in the pathophysiology of premenstrual changes (PMC) possibly through their interaction with neurotransmitter systems in the brain. The serotonergic system, an important central modulator of mood and behavior which is involved in the pathophysiology of affective disorders has been suggested to play a role in the genesis of dysphoric PMC. Blood platelet serotonin (5-HT) uptake and imipramine (IMI) binding have been shown to share similarities with serotonergic mechanisms in the brain thus enabling the study of serotonergic mechanisms. In this study, we report on platelet 5-HT uptake and IMI receptor binding which were simultaneously studied in women with PMC. Subjects with PMC showed a large interindividual variability with no consistent typical pattern or change during the late symptomatic as compared to the early nonsymptomatic luteal phase. Their IMI receptor binding, however, was lower compared to controls already during the early luteal phase before they developed symptoms and was similar during the symptomatic phase. This might suggest a preexistent vulnerability to the development of dysphoric PMC that might be related to impaired gonadal hormone modulation of the serotonergic system.

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“…Accordingly, some theoretical researches were conducted on the premenstrual syndrome which is a women-specific health problem, and the verification of the effects of health functional foods to help the health control regarding premenstrual syndromes [4][5][6].…”

Section: Introductionmentioning

confidence: 99%