Prenatal diagnosis of fetal cerebral abnormalities by ultrasonography and magnetic resonance imaging

D’ercole, C.; Girard, Nadine; Boubli, L.; Potier, A.; C, Chagnon; Raybaud, Charles; Blanc, B.

doi:10.1016/0028-2243(93)90198-l

Cited by 46 publications

(30 citation statements)

References 17 publications

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“…MR imaging demonstrated ventriculomegaly in 14 fetuses: mild ventriculomegaly in 12 and severe in two cases (twin fetuses, figures 6,7,8). In four cases the ventriculomegaly was isolated (figure 1).…”

Section: Resultsmentioning

confidence: 91%

“…The sylvian scissure begins as a shallow depression at 14 weeks gestation and subsequently becomes grooved. alies), to detect possible brain anomalies 7,8,9,23 . Because of the increasing use of MR imaging to assess fetal central nervous system (CNS) anomalies, it is important to establish the normal aspect of fetal brain (with respect to gestational age) and to evaluate whether this normal aspect is altered in fetuses with CNS anomalies 26 .…”

Section: Discussionmentioning

confidence: 99%

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Fetal MR Imaging

D’Aprile¹,

Strada²,

Tarantino³

et al. 2004

Rivista di Neuroradiologia

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Although sonography (US) is the first imaging technique for evaluating the developing fetus, significant limitations exist in the sonographic prenatal diagnosis of many brain disorders and in the evaluation of cerebral anatomy. At present, the role of MR imaging in the diagnosis of prenatal anomalies is confined to determining the underlying cause of non-specific fetal abnormalities detected sonographically, especially in fetal brain malformations, or when US is equivocal or limited. In particular, the major indication for MR study is ventriculomegaly, because this sign could be associated with different anomalies (malformations, ischemic disease and cerebral destructive lesions); other indications for MRI include maternal infections and genetic syndromes. MR imaging is an important adjunctive tool for prenatal imaging in those instances where complex anomalies are suspected by US, when fetal surgery is contemplated, or when a definitive diagnosis cannot be determined. In this work we report our experience of fetal MRI in fetuses with suspect cerebral anomalies previously detected by US.

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Section: Resultsmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Fetal MR Imaging

D’Aprile¹,

Strada²,

Tarantino³

et al. 2004

Rivista di Neuroradiologia

View full text Add to dashboard Cite

show abstract

“…To date, technical advances in motion correction for MR images of the moving fetus [22][23][24][25] have focused on anatomical MR images of the fetal brain. Very few studies have addressed fetal motion correction in fMRI studies.…”

Section: Introductionmentioning

confidence: 99%

Robust preprocessing for stimulus-based functional MRI of the moving fetus

et al. 2016

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Abstract. Fetal motion manifests as signal degradation and image artifact in the acquired time series of blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) studies. We present a robust preprocessing pipeline to specifically address fetal and placental motion-induced artifacts in stimulus-based fMRI with slowly cycled block design in the living fetus. In the proposed pipeline, motion correction is optimized to the experimental paradigm, and it is performed separately in each phase as well as in each region of interest (ROI), recognizing that each phase and organ experiences different types of motion. To obtain the averaged BOLD signals for each ROI, both misaligned volumes and noisy voxels are automatically detected and excluded, and the missing data are then imputed by statistical estimation based on local polynomial smoothing. Our experimental results demonstrate that the proposed pipeline was effective in mitigating the motion-induced artifacts in stimulus-based fMRI data of the fetal brain and placenta.

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“…However, in most cases the cause remains unknown and is considered to be idiopathic (or constitutional). In addition, ventricular dilatation is one of the most common clinical conditions [1] in cases referred for fetal brain magnetic resonance imaging (MRI) (38% in our experience), the most challenging condition being the evaluation of mild ventricular dilatation.…”

Section: Introductionmentioning

confidence: 99%