Prenatal ultrasound characterization of the suprarenal mass: distinction between neuroblastoma and subdiaphragmatic extralobar pulmonary sequestration

Curtis, Michael; Mooney, David P.; Vaccaro, Therese; Williams, Joseph B; Cendron, Marc; Shorter, Nicholas A.; Sargent, Steven K.

doi:10.7863/jum.1997.16.2.75

Cited by 84 publications

(50 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Differential diagnosis in right-sided masses includes hamartoma and hemorrhage, which more commonly arise diagnostic dilemmas when compared with left sided masses such as sequestration. Bilateral involvement of adrenal glands, cystic metastatic lesions in the liver, thickened walls, calcifications, cystic lesions with solid components and increased color-coding in Doppler US favors the diagnosis of NB [8][9][10]. Increased serum NSE is the major biochemical finding that supports the diagnosis of cystic NB.…”

Section: Discussionmentioning

confidence: 82%

“…Haberal et al identified a case of a right sided-NB, which was misdiagnosed as infantile hemangioendothelioma of the liver that caused severe consumption coagulopathy and bleeding into the adrenal glands [9]. The differential diagnosis of left cystic adrenal NB includes extralobar sequestration, especially in the prenatal period [10]. Differential diagnosis in right-sided masses includes hamartoma and hemorrhage, which more commonly arise diagnostic dilemmas when compared with left sided masses such as sequestration.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Bilateral Cystic Adrenal Neuroblastoma with Cystic Liver Metastases

Aslan¹,

Alış²,

Kalyoncu³

et al. 2017

APSP J Case Rep

View full text Add to dashboard Cite

Bilateral congenital cystic adrenal neuroblastoma (NB) with cystic liver metastasis is a very rare condition and only few cases have been reported in the literature. Herein we report a case of a congenital bilateral cystic adrenal NB with cystic liver metastasis and briefly discuss characteristic imaging features of cystic NB. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. CASE REPORTA 3-month-old baby presented to clinic with marked abdominal distention. His medical history was insignificant. Laboratory findings were within normal limits except for mildly elevated serum transaminases (AST: 54 IU/L, ALT: 45 IU/L) and neuron-specific enolase (NSE: 21.9 ng/ml). An abdominal ultrasound (US) was performed. US revealed 10x10x12cm heterogeneous cystic mass in the right suprarenal region, which was displacing the right kidney downward. US scan also showed a 2x2x2cm anechoic cystic mass in the left adrenal gland. Borders between the right lobe of the liver and lesion were indistinguishable. Multiple anechoic cystic lesions up to 10mm were detected in the right and the left lobes of the liver. Intravenous contrast enhanced magnetic resonance imaging (MRI) was performed for further evaluation of the lesions to avoid the ionizing radiation of computed tomography (CT) scan. MRI revealed that both lesions were cystic in nature and thick walls of the lesion were enhanced with contrast. No solid components were detected in lesions. Calcifications were noted in the inferior-posterior part of the right-sided suprarenal mass. Lesions in the liver also showed no contrast enhancement on MRI (Fig.1). Cystic nature of the lesion, mildly increased NSE and presence of multiple cystic lesions in the liver, were supporting the diagnosis of congenital bilateral adrenal NB with cystic liver metastasis. Bone marrow aspiration was negative for tumor cells and a probable diagnosis of neuroblastoma was made. In the following days, the patient started to develop a significant shortness of breath due to rapidly growing abdominal masses (NSE also increased) and underwent operation. During the operation, the right-sided lesion was dissected carefully from the surface of the liver and the right kidney. Then both lesions in the adrenal gland were completely excised. Aspiration was performed from one of the cystic lesions in the liver for histopathologic examination. The pathology specimen revealed stroma poor, poorly differentiated cystic NB with 10 fold N-myc amplification, which is favoring bad prognosis according to

show abstract

Section: Discussionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 99%

Bilateral Cystic Adrenal Neuroblastoma with Cystic Liver Metastases

Aslan¹,

Alış²,

Kalyoncu³

et al. 2017

APSP J Case Rep

View full text Add to dashboard Cite

show abstract

“…Approximately 10% of extrapulmonary sequestrations are found intra-abdominally (IEPS), and 90% of IEPSs occur on the left side. 9,20,21 Intra-abdominal extralobar pulmonary sequestrations occur predominantly as sharply circumscribed masses in the left upper quadrant between the diaphragm and kidney, separated from the normal adrenal gland. Indeed, this is probably the most common left suprarenal mass detected in the fetus.…”

Section: Discussionmentioning

confidence: 99%

“…Follow-up sonography is clearly important. Curtis et al 21 presented a well-designed diagnostic and treatment algorithm for a prenatally detected suprarenal mass. A recent report of a 13-month-old boy with primary pulmonary rhabdomyosarcoma that originated within a CCAM illustrated the need for careful follow-up in cases of CCAM.…”

Section: Discussionmentioning

confidence: 99%

Presumptive Intrahepatic Congenital Cystic Adenomatoid Malformation

Markhardt

Farmer

Filly

2003

Journal of Ultrasound in Medicine

View full text Add to dashboard Cite

ongenital cystic adenomatoid malformation (CCAM) and extralobar pulmonary sequestration (EPS) are 2 rare types of bronchopulmonary malformations that typically appear in infancy and childhood. A CCAM is a hamartomatous lesion of the lung, thought to be the result of the cessation of bronchiolar maturation with overgrowth of mesenchymal elements. An EPS is a discrete mass of lung tissues separate from the tracheobronchial tree and is supplied by a systemic vascular source (usually aortic). As well, it forms outside the normal pleural investment. Conran and Stocker 1 analyzed 50 cases of EPS and found that 50% (23 of 46) were associated with a coexistent CCAM. Rare cases of intra-abdominal EPS (IEPS) have been reported in the literature, and in these cases, CCAMs commonly occur within the pulmonary sequesterant. [2][3][4][5][6][7][8][9][10][11] We present an interesting case of CCAM manifesting within the liver of a patient treated prenatally for a large pulmonary type II CCAM and review the reported cases of IEPS with CCAM.

show abstract

“…The major differential diagnosis of a prenatal/neonatal suprarenal mass includes adrenal hemorrhage and neuroblastoma (5). Adrenal hemorrhage may be echogenic when first detected but becomes hypoechoic or anechoic within several days or shrinks in the first month of life (6).…”

Section: Discussionmentioning

confidence: 99%

A Case of Intra - Abdominal Extralobar Pulmonary Sequestration: Prenatal Detection, Postnatal Diagnostic Approach and Outcome

Eroğlu

Denizoğlu

Ergün

2017

Gynecol Obstet Reprod Med

View full text Add to dashboard Cite

This paper describes the perinatal and postnatal outcome of a case considered to have a fetal intra-abdominal extralobar pulmonary sequestration.Routine midtrimester fetal ultrasonographic scan detected an abdominal echogenic mass between aorta and stomach. It was considered primarily as an intra-abdominal extralobar pulmonary sequestration. At postnatal 2 months, computed tomography scan with intravenous contrast described it as an extralobar pulmonary sequestration at the level of diaphragmatic hiatus by showing the aberrant blood supply to the sequestration with venous drainage into the portal confluence. The patient is now 4 years old and asymptomatic; she is being followed-up by a pediatric surgeon.Intra-abdominal extralobar pulmonary sequestrations usually remain asymptomatic throughout life; they may be safely observed without surgery unless they become symptomatic or show any change in the characteristics of the radiologic appearance.

show abstract

Prenatal ultrasound characterization of the suprarenal mass: distinction between neuroblastoma and subdiaphragmatic extralobar pulmonary sequestration

Cited by 84 publications

References 6 publications

Bilateral Cystic Adrenal Neuroblastoma with Cystic Liver Metastases

Bilateral Cystic Adrenal Neuroblastoma with Cystic Liver Metastases

Presumptive Intrahepatic Congenital Cystic Adenomatoid Malformation

A Case of Intra - Abdominal Extralobar Pulmonary Sequestration: Prenatal Detection, Postnatal Diagnostic Approach and Outcome

Contact Info

Product

Resources

About