Preoperative infliximab treatment and postoperative complications after laparoscopic restorative proctocolectomy with ileal pouch–anal anastomosis: a case-matched study

Abstract

The study findings showed no adverse impact from previous infliximab therapy on the laparoscopic IPAA postoperative course.

Role of laparoscopic surgery in the treatment of ulcerative colitis; short- and mid-term results

“…In several studies, prior biological therapy was considered to have a negative effect on the results of the surgical treatment in UC [20,21], although this is not supported by other observations [22][23][24] or the most recent case-matched study [25]. Our study indicated only four cases of an early postoperative complication among the 16 patients who had received infliximab treatment and therefore suggests that prior biological therapy is not associated with a higher rate of complications.…”

Guidelines for the management of ulcerative colitis. Recommendations of the Working Group of the Polish National Consultant in Gastroenterology and the Polish Society of Gastroenterology

“…W innych badaniach natomiast wykazano jedynie zwiększenie ryzyka wy stąpienia powikłań infekcyjnych [80,81]. Istnieją jednak dane przeczące także i takiej zależności.…”

Pediatric chronic ulcerative colitis: does infliximab increase post–ileal pouch anal anastomosis complications?

“…Gender distribution was equivalent with both groups having 45% male and 55% female. The mean age in the IFX group was slightly younger with an average of 15.0 years (range 11 to 18) compared to 16.4 years (range, [8][9][10][11][12][13][14][15][16][17][18] in the control group.…”

“…Reports in the adult literature provide conflicting results of infliximab's potential to impact postoperative outcomes [3][4][5][6][7][8][9]. However, to date, there have been no studies examining the post-IPAA effects of preoperative treatment with infliximab specifically in children.…”