Preparation and Characterization of a Complex of Paeonol and Hydroxypropyl-β-cyclodextrin

Chen, Chungang; Xu, Xiufeng; Li, Yaoran; Ma, Haile

doi:10.4314/tjpr.v14i9.4

Cited by 1 publication

(1 citation statement)

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“…The characteristic peaks of standard paeonol appeared at 12.06, 16.67, 23.77, and 25.7, and these characteristic peaks could also be observed in the diffraction pattern of purified paeonol. The results of this work were consistent with the results of previous studies, [ 40 ] indicating that the crystal structure of paeonol purified by ASR did not change.…”

Section: Resultssupporting

confidence: 93%

Extraction and purification of paeonol from Moutan Cortex by a combined method of steam distillation and antisolvent recrystallization to reduce energy consumption and carbon dioxide emissions

et al. 2022

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This study aimed to obtain paeonol with high purity by using the combination of steam distillation and antisolvent recrystallization (ASR) and to reduce the energy consumption and CO2 emission in the preparation process. First, different experimental parameters were optimized by response surface methodology (RSM). Under the optimal conditions, the purity and yield of the as‐obtained paeonol were about 98% and 56.97%, respectively. The physicochemical properties of purified paeonol were tested, showing consistency with those of standard paeonol. The energy consumption and CO2 emission of the preparation process of ASR and single‐solvent recrystallization were also investigated. Results showed that the energy consumption and CO2 emission of ASR were about 4.41 J/mg and 0.006 kg/mg, respectively, which were 6.89 J/mg and 0.0095 kg/mg lower than those of ethanol recrystallization, respectively, and 50.22 J/mg and 0.0144 kg/mg lower than methanol those of recrystallization, respectively. The above results showed that ASR could obtain paeonol with high purity in a high‐efficiency, low‐energy, and environmentally protective manner.

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Section: Resultssupporting

confidence: 93%