Preparation and Characterization of Chitosan-Coated  Poly(l-Lactic Acid) Fibers and Their Braided Rope

Furuike, Tetsuya; Nagahama, Hideaki; Chaochai, Thitirat; Tamura, Hiroshi

doi:10.3390/fib3040380

Cited by 12 publications

(5 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Specimens of 5 × 5 × 5 mm were frozen at −20 • C and dried in a lyophilizer (ilshin BioBase, Dongducheon, Republic of Korea) at −60 • C for 24 h. The weight loss after immersion in PBS at pH 7.4 and 37 • C for 28 days was recorded using an analytical balance. The material degradation was calculated from the normalized difference of the initial weight W 0 and the weight W t after the desired time t according to Equation (2) [41], as follows:…”

Section: Hybrid Degradation Testmentioning

confidence: 99%

Novel Organic–Inorganic Nanocomposite Hybrids Based on Bioactive Glass Nanoparticles and Their Enhanced Osteoinductive Properties

Cohn,

Bradtmüller,

Zanotto

et al. 2024

Biomolecules

View full text Add to dashboard Cite

Inorganic–organic hybrid biomaterials have been proposed for bone tissue repair, with improved mechanical flexibility compared with scaffolds fabricated from bioceramics. However, obtaining hybrids with osteoinductive properties equivalent to those of bioceramics is still a challenge. In this work, we present for the first time the synthesis of a class II hybrid modified with bioactive glass nanoparticles (nBGs) with osteoinductive properties. The nanocomposite hybrids were produced by incorporating nBGs in situ into a polytetrahydrofuran (PTHF) and silica (SiO2) hybrid synthesis mixture using a combined sol–gel and cationic polymerization method. nBGs ~80 nm in size were synthesized using the sol–gel technique. The structure, composition, morphology, and mechanical properties of the resulting materials were characterized using ATR-FTIR, 29Si MAS NMR, SEM-EDX, AFM, TGA, DSC, mechanical, and DMA testing. The in vitro bioactivity and degradability of the hybrids were assessed in simulated body fluid (SBF) and PBS, respectively. Cytocompatibility with mesenchymal stem cells was assessed using MTS and cell adhesion assays. Osteogenic differentiation was determined using the alkaline phosphatase activity (ALP), as well as the gene expression of Runx2 and Osterix markers. Hybrids loaded with 5, 10, and 15% of nBGs retained the mechanical flexibility of the PTHF–SiO2 matrix and improved its ability to promote the formation of bone-like apatite in SBF. The nBGs did not impair cell viability, increased the ALP activity, and upregulated the expression of Runx2 and Osterix. These results demonstrate that nBGs are an effective osteoinductive nanoadditive for the production of class II hybrid materials with enhanced properties for bone tissue regeneration.

show abstract

Section: Hybrid Degradation Testmentioning

confidence: 99%

Novel Organic–Inorganic Nanocomposite Hybrids Based on Bioactive Glass Nanoparticles and Their Enhanced Osteoinductive Properties

Cohn,

Bradtmüller,

Zanotto

et al. 2024

Biomolecules

View full text Add to dashboard Cite

show abstract

“…The removal of dyes from waters becomes a major challenge due to the difficulty in treating such wastewaters by conventional treatment methods such as chemical and biological oxidation methods [3,4]. However, the commonly used technique for removal of dyes from wastewater is adsorption [3][4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

“…Chitosan can be considered as one of the most efficient adsorbents for the removal of pollutants from water [8][9][10][11]. It is a deacetylated derivative of chitin [5,8,9,12]. As one of the most representative biopolymers, it is a multifunctional polysaccharide comprising of copious chelating groups including primary and secondary hydroxyl groups, as well as highly reactive amino groups [7,13].…”

Section: Introductionmentioning

confidence: 99%

Effect of Chitosan as Active Substance in Hydrogel on the Diffusion of Dyes

KLUČÁKOVÁ

2023

NANOCON Conference Proeedings

View full text Add to dashboard Cite

Cation active chitosan was studied as the active substance incorporated into an inert hydrogel to affect its transport and barrier properties. The inert hydrogel was based on thermo-reversible agarose which can be prepared in defined shape and size required for the mathematical description of studied transport. Amido Black 10B was chosen as a model anionic dye able to interact with chitosan. Agarose hydrogels with the contents of chitosan equal to 2, 5, and 10 g per gram of hydrogel were prepared. Diffusion experiments were realized at three different temperatures (30, 40, and 50 °C).Transport experiments in hydrogels provided the values of effective diffusion coefficients involving the effect of interactions between chitosan and dye under given conditions. The incorporation of chitosan into inert hydrogel resulted in the decrease in the dye diffusivity. An apparent equilibrium constant as the ratio between immobilized and free movable dye particles was determined on the basis of the comparison of dye diffusivities in hydrogels enriched by chitosan with values obtained for pure agarose hydrogel. The increase in temperature enhanced diffusion rate as expected. The increase in diffusion coefficients with increasing temperature showed on the predominant influence of higher mobility in comparison with temperature dependence of reaction rate.

show abstract

“…Several techniques have recently been reported to modify PLA surfaces. For example, PLA surfaces can be coated by hydrophilic polymers, such as proteins, chitosan (CS), and sodium alginate (SA) by alkaline, enzymatic, or plasma treatments [10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Preparation of Chitosan-Coated Poly(L-Lactic Acid) Fibers for Suture Threads

Komoto

Ikeda

Furuike

et al. 2018

Fibers

Self Cite

View full text Add to dashboard Cite

Poly(L-lactic acid) (PLA) is a biodegradable fiber, and a promising material for use in biomedical applications. However, its hydrophobicity, low hydrolyzability, and poor cell adhesion can be problematic in some cases; consequently, the development of improved PLA-based materials is required. In this study, chitosan-coated (CS-coated) PLA was prepared by plasma treatment and the layer-by-layer (LBL) method. Plasma treatment prior to CS coating effectively hydrophilized and activated the PLA surface. The LBL method was used to increase the number of CS and sodium alginate (SA) coating layers by electrostatically superposing alternating anionic and cationic polymers. The prepared fibers were characterized by tensile testing, scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), nitrogen analysis and degradation testing, which revealed that the 100 W plasma treatment for 60 s was optimum, and that plasma treatment and the LBL method effectively coated CS onto the PLA fibers. The existence or not of a coating on the PLA fiber did not appear to influence the degradation of the fiber, which is ascribable to the extremely thin coating, as evidenced by nitrogen analysis and SEM. The CS-coated PLA fibers were prepared without damaging the PLA surface and can be used in biomaterial applications such as suture threads.

show abstract

Preparation and Characterization of Chitosan-Coated Poly(l-Lactic Acid) Fibers and Their Braided Rope

Cited by 12 publications

References 31 publications

Novel Organic–Inorganic Nanocomposite Hybrids Based on Bioactive Glass Nanoparticles and Their Enhanced Osteoinductive Properties

Novel Organic–Inorganic Nanocomposite Hybrids Based on Bioactive Glass Nanoparticles and Their Enhanced Osteoinductive Properties

Effect of Chitosan as Active Substance in Hydrogel on the Diffusion of Dyes

Preparation of Chitosan-Coated Poly(L-Lactic Acid) Fibers for Suture Threads

Contact Info

Product

Resources

About