Preparation and characterization of chitosan-silver/hydroxyapatite composite coatings onTiO2 nanotube for biomedical applications

Yan, Yajing; Zhang, Xuejiao; Li, Caixia; Huang, Yong; Ding, Qiongqiong; Pang, Xin

doi:10.1016/j.apsusc.2015.01.136

Cited by 74 publications

(40 citation statements)

References 29 publications

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“…In another study, chitosan-based films containing silver nanoparticles were shown to have wetting properties highly sensitive to the fraction of AgNPs [14]. Coatings composed of chitosan, silver, and hydroxyapatite exhibited antibacterial activity and were nontoxic to MC3T3-E1 cells [15]; chitosan coatings with silver-decorated calcium phosphate microspheres lowered bacterial viability up to 90% [16], and silver-doped β-tricalcium phosphate composite coatings exhibited antibacterial activity and no adverse cytotoxic effects towards the cell line MG-63 [17]. Chitosan-cellulose composite films with AgNPs demonstrated excellent antibacterial properties against Escherichia coli and Staphylococcus aureus [18].…”

Section: Introductionmentioning

confidence: 98%

Electrophoretic Deposition and Characteristics of Chitosan–Nanosilver Composite Coatings on a Nanotubular TiO2 Layer

et al. 2020

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The surface treatment of titanium implants has been applied mainly to increase surface bioactivity and, more recently, to introduce antibacterial properties. To this end, composite coatings have been investigated, particularly those based on hydroxyapatite. The present research was aimed at the development of another coating type, chitosan–nanosilver, deposited on a Ti13Zr13Nb alloy. The research comprised characterization of the coating’s microstructure and morphology, time-dependent nanosilver dissolution in simulated body fluid, and investigation of the nanomechanical properties of surface coatings composed of chitosan and nanosilver, with or without a surface-active substance, deposited at different voltages for 1 min on a nanotubular TiO2 layer. The microstructure, morphology, topography, and phase composition were examined, and the silver dissolution rate in simulated body fluid, nanoscale mechanical properties, and water contact angle were measured. The voltage value significantly influenced surface roughness. All specimens possessed high biocompatibility. The highest and best adhesion of the coatings was observed in the absence of a surface-active substance. Silver dissolution caused the appearance of silver ions in solution at levels effective against bacteria and below the upper safe limit value.

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Section: Introductionmentioning

confidence: 98%

Electrophoretic Deposition and Characteristics of Chitosan–Nanosilver Composite Coatings on a Nanotubular TiO2 Layer

et al. 2020

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“…The thicknesses of the obtained coatings (5-10μm) are similar to the thicknesses of the coating prepared by some other methods [49,50].…”

Section: Accepted Manuscriptmentioning

confidence: 73%

Synthesis of the hydroxyapatite coatings on the Ti substrates by mechanical alloying

Zadorozhnyy

Kaevitser

Kopylov³

et al. 2015

Surface and Coatings Technology

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“…This allowed for the development of a coating with both osseointegration and biocide properties. Thus, there was no need to add more coatings [ 31 ], such as one coating of HA for osseointegration and another coating of Ag for biocide properties; or to employ two or more reagents to allow the deposition as reported by Yan et al (Ca(NO 3 ) 2 , NH 4 H 2 PO 4 and AgNO 3 ) [ 32 ].…”

Section: Discussionmentioning

confidence: 99%

Development of HA/Ag-NPs Composite Coating from Green Process for Hip Applications

et al. 2017

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In the present study, biological hydroxyapatite (HA) was obtained from bovine bones through a thermal process. A total of 0% and 1% of silver nanoparticles (Ag-NPs) synthesized from Opuntia ficus (nopal) were added to the biological hydroxyapatite coatings using an atmospheric plasma spray (APS) on a Ti6Al4V substrate. Following this, its antimicrobial efficiency was evaluated against the following bacterial strains: Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. This was conducted according to the Japanese Industrial Standard (JIS) Z2801:2000 “Antimicrobial Product-Test for Antimicrobial Activity and Efficacy”. Scanning electron microscopy (SEM) showed that the silver nanoparticles (Ag-NPs) were evenly distributed on the coating surface. Energy dispersive X-ray spectroscopy (EDX) shows that apatite deposition occurs on a daily basis, maintaining a Ca/P rate between 2.12 and 1.45. Biocompatibility properties were evaluated with osteoblast-like cells (MC3T3-E1) by single-cell gel electrophoresis assay and Tali image cytometry.

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Preparation and characterization of chitosan-silver/hydroxyapatite composite coatings onTiO2 nanotube for biomedical applications

Cited by 74 publications

References 29 publications

Electrophoretic Deposition and Characteristics of Chitosan–Nanosilver Composite Coatings on a Nanotubular TiO2 Layer

Electrophoretic Deposition and Characteristics of Chitosan–Nanosilver Composite Coatings on a Nanotubular TiO2 Layer

Synthesis of the hydroxyapatite coatings on the Ti substrates by mechanical alloying

Development of HA/Ag-NPs Composite Coating from Green Process for Hip Applications

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