Preparation and characterization of Fe 3 O 4 -Ag 2 O quantum dots decorated cellulose nanofibers as a carrier of anticancer drugs for skin cancer

Fakhri, Ali; Tahami, Shiva; Nejad, Pedram Afshar

doi:10.1016/j.jphotobiol.2017.08.032

Cited by 62 publications

(31 citation statements)

References 32 publications

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“…CNF nanocomposites for drug delivery may be fabricated using inorganic nanoparticles, such as titanium oxide [242] and magnetite. Magnetite (Fe 3 O 4 )-silver(I) oxide (Ag 2 O) quantum dots/cellulose fiber nanocomposites have been fabricated to deliver a chemotherapeutic cocktail of etoposide and MTX for lung, breast, and skin cancer [185]. The drugs were dissolved in water and added to the aqueous dispersion of Fe 3 O 4 -Ag 2 O quantum dots/cellulose fibers, followed by drying.…”

Section: Cnf Composite Filmsmentioning

confidence: 99%

“…The release of etoposide and MTX was then evaluated at physiological pH. Etoposide was released at a constant rate, recording ~ 79% in the buffer after 24 h, and the MTX was released at a prolonged constant rate, requiring a longer incubation time to reach equilibrium: ~ 64% release after 30 h [185]. The different release kinetics of drugs may be explained by the difference in the solubilities: etoposide is more soluble than methotrexate and can readily be released.…”

Section: Cnf Composite Filmsmentioning

confidence: 99%

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Recent advances in nanoengineering cellulose for cargo delivery

Sheikhi

Hayashi

Eichenbaum

et al. 2019

Journal of Controlled Release

103

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The recent decade has witnessed a growing demand to substitute synthetic materials with naturally-derived platforms for minimizing their undesirable footprints in biomedicine, environment, and ecosystems. Among the natural materials, cellulose, the most abundant biopolymer in the world with key properties, such as biocompatibility, biorenewability, and sustainability has drawn significant attention. The hierarchical structure of cellulose fibers, one of the main constituents of plant cell walls, has been nanoengineered and broken down to nanoscale building blocks, providing an infrastructure for nanomedicine. Microorganisms, such as certain types of bacteria, are another source of nanocelluloses known as bacterial nanocellulose (BNC), which benefit from high purity and crystallinity. Chemical and mechanical treatments of cellulose fibrils made up of alternating crystalline and amorphous regions have yielded cellulose nanocrystals (CNC), hairy CNC (HCNC), and cellulose nanofibrils (CNF) with dimensions spanning from a few nanometers up to several microns. Cellulose nanocrystals and nanofibrils may readily bind drugs, proteins, and nanoparticles through physical interactions or be chemically modified to covalently accommodate cargos. Engineering surface properties, such as chemical functionality, charge, area, crystallinity, and hydrophilicity, plays a pivotal role in controlling the cargo loading/releasing capacity and rate, stability, toxicity, immunogenicity, and biodegradation of nanocellulose-based delivery platforms. This review provides insights into the recent advances in nanoengineering cellulose crystals and fibrils to develop vehicles, encompassing colloidal *

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Section: Cnf Composite Filmsmentioning

confidence: 99%

Section: Cnf Composite Filmsmentioning

confidence: 99%

Recent advances in nanoengineering cellulose for cargo delivery

Sheikhi

Hayashi

Eichenbaum

et al. 2019

Journal of Controlled Release

103

View full text Add to dashboard Cite

show abstract

“…With good biocompatibility and magnetic effect, Nano-Fe 3 O 4 had a wide application in the treatment of tumors and magnetic resonance imaging [109]. Zhang et al [110] studied the application of Nanoferroferric oxide in rats' hydrocrania CT imaging, which could be used as a photographic developer.…”

Section: Biomedical Sciencesmentioning

confidence: 99%

Preparation and Potential Applications of Super Paramagnetic Nano-Fe3O4

et al. 2018

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Ferroferric oxide nanoparticle (denoted as Nano-Fe 3 O 4 ) has low toxicity and is biocompatible, with a small particle size and a relatively high surface area. It has a wide range of applications in many fields such as biology, chemistry, environmental science and medicine. Because of its superparamagnetic properties, easy modification and function, it has become an important material for addressing a number of specific tasks. For example, it includes targeted drug delivery nuclear magnetic resonance (NMR) imaging in biomedical applications and in environmental remediation of pollutants. Few articles describe the preparation and modification of Nano-Fe 3 O 4 in detail. We present an evaluation of preparation methodologies, as the quality of material produced plays an important role in its successful application. For example, with modification of Nano-Fe 3 O 4 , the surface activation energy is reduced and good dispersion is obtained.

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“…Technically, the cellulose-based materials are of high reactivity, high surface area, high stability, high biocompatibility value, high safety and nontoxicity properties, and high biodegradability. 18 , 19 …”

Section: Introductionmentioning

confidence: 99%

Insight into the Loading and Release Properties of an Exfoliated Kaolinite/Cellulose Fiber (EXK/CF) Composite as a Carrier for Oxaliplatin Drug: Cytotoxicity and Release Kinetics

et al. 2020

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Kaolinite layers were exfoliated as single sheets and admixed with cellulose fibers, forming an advanced exfoliated kaolinite/cellulose fiber (EXK/CF) composite, which was characterized as a promising carrier for the oxaliplatin (OL) drug to induce safety as well as the therapeutic effect. The EXK/CF composite exhibited promising loading capacity and achieved an experimental value of 670 mg/g and an expected theoretical value of 704.4 mg/g. The loading behavior of OL using the EXK/CF composite followed the pseudo-first-order kinetic model and the Langmuir equilibrium model, achieving an adsorption energy of 7.7 kJ/mol. This suggested physisorption and homogeneous loading behavior of the OL molecules in a monolayer form. The release profile of OL from EXK/CF continued for about 100 h with maximum release percentages of 86.4 and 95.2% in the phosphate and acetate buffers, respectively. The determined diffusion exponent from the Korsmeyer–Peppas kinetic model suggested non-Fickian transport behavior of the OL molecules and releasing behavior controlled by erosion as well as diffusion mechanisms. Regarding the cytotoxic effect, the EXK/CF composite has a high safety impact on the normal colorectal cells (CCD-18Co) and higher toxic impacts on the colorectal cancer cell (HCT116) than the free oxaliplatin drug.

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Preparation and characterization of Fe 3 O 4 -Ag 2 O quantum dots decorated cellulose nanofibers as a carrier of anticancer drugs for skin cancer

Cited by 62 publications

References 32 publications

Recent advances in nanoengineering cellulose for cargo delivery

Recent advances in nanoengineering cellulose for cargo delivery

Preparation and Potential Applications of Super Paramagnetic Nano-Fe3O4

Insight into the Loading and Release Properties of an Exfoliated Kaolinite/Cellulose Fiber (EXK/CF) Composite as a Carrier for Oxaliplatin Drug: Cytotoxicity and Release Kinetics

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