Preparation and Characterization of Zirconium Oxide-Doped Hydroxyapatite

Abstract

Various bioceramic materials including zirconia and hydroxyapatite have been developed for various applications. Hydroxyapatite (Ca10(PO4)6(OH)2, HAp) is one of the most interesting features of calcium phosphate-based bioceramic that widely used in various applications especially for bio-application, bone engineering, and dentistry. However, the applications of pristine HAp have limited due to low load bearing applications. The wet chemical precipitation techniques was used to synthesize the solids based on zirconia. Hydroxyapatite and zirconia powder (0-30 weight %) were mixed homogeneously. Structure and morphological were characterized by SEM JEOL-JSM-T330A. The presence of functional group was observed by FTIR. Hardness value of material was measured by using Vickers hardness test measurement. Through this techniques, pure hydroxyapatite precipitate was obtained. Sintering temperature is an important factor that could influence the hardness of zirconia-doped hydroxyapatite. Based on the SEM observation, zirconia-doped hydroxyapatite were developed in blended morphology. FTIR results shows the interaction between hydroxyapatite and zirconia. Increasing zirconia increased the hardness value of zirconia-doped hydroxyapatite. Eventually, these ceramic-based materials could be developed for dental materials applications.

Investigation of Coatings, Corrosion and Wear Characteristics of Machined Biomaterials through Hydroxyapatite Mixed-EDM Process: A Review

“…Studies reported a less than 2% bio-implant failure after following up for several years, assuring the clinical success of the HA powder (HAp) in biomedical applications [41][42][43][44][45][46][47]. However, sudden failure of HAp-based bio-implants was reported recently, due to deterioration resulting from faster dissolution of the HAp under body fluid conditions as HAp is brittle in nature and has poor crystallinity [47][48][49][50][51][52]. Researchers have been investigating the effects of a HAp mixed-EDM process on modified surface characteristics over the last decade.…”

Hydrothermal synthesis of valve metal Zr-doped titanate nanofibers for bone tissue engineering

“…Sterically, the ZrO6 that's larger than the TiO6 would logically stay on the nanofiber surface to minimize the distortion of the nanofiber's TiO6-dominated crystal lattice. Thus-surfaced ZrO6 can potentially help bone-tissue adhesion, as well-established in the literature [27,33,34] . Further, the interlayer K + cations near the ZrO6 in the K-titanate nanofiber could be more easily (hence more rapidly) replaced by Ca 2+ cations in body fluid to promote the rapid formation of hydrated calcium phosphates (or hydroxyapatite) on the nanofiber, like other labs reported in the literature using the simulated body fluid (SBF) [18,35] .…”

“…The strong bonding between the hydroxyapatite coating and the titanate nanofiber substrate surface can chemically secure the bone tissue's long-term strong adhesion to the nanofibersupported hydroxyapatite, forming an ideal osteogenic/osteoconductive environment [18] . The thusoptimized surface of titanate nanofibers for developing a new bone scaffold can complement other lab methods in promoting the bone scaffold's osteoconductivity [27,33,34,36] . In basic chemistry, this work has demonstrated an innovative and cost-effective method for doping Zr (IV) into the titanate nanofiber lattice, which seems new and important in orthopedic nanomedicine.…”

<p>Pengukuran kekerasan karbonat apatit dengan penguat zirkonia sebagai aplikasi implan gigi</p><p>Hardness evaluation of carbonate apatite reinforced with zirconia as a dental implant</p>

“…5 Kelemahan karbonat apatit tersebut dapat diatasi dengan penambahan bahan keramik lainnya yaitu zirkonia yang akan meningkatkan kekuatan mekanik bahan keramik yang pertama. 6 Zirkonia adalah material keramik yang memiliki sifat biokompatibilitas yang baik, sifat mekanik yang baik, tahan terhadap korosi dan resistensi terhadap kerusakan. Sifat mekanik yang tinggi dari zirkonia dapat dimanfaatkan sebagai bahan penguat dari keramik yang pertama.…”

“…Karakteristik sintering tahap awal adalah adanya gambaran ikatan yang terbatas pada antar partikel . 6 Selain itu beberapa daerah sintering dapat teramati dengan baik, hal ini disebabkan oleh ukuran partikel yang lebih kecil. Struktur zirkonia merupakan keramik bioinert yaitu stabil dalam tubuh manusia dan tidak menunjukkan respon yang berbahaya.…”