Preparation and Dynamic Behavior of Protein-Polymer Complexes Formed with Polymer-Binding Peptides

Ravishankar, Samyukta; Suzuki, Seigo; Sawada, Tatsuo; Lim, Sierin; Serizawa, Takeshi

doi:10.1246/bcsj.20200021

Cited by 6 publications

(6 citation statements)

References 28 publications

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“…Lim, Serizawa, and co-workers developed complexes of a protein (ferritin) and thermo-responsive polymer (poly(N-isopropylacrylamide)) with the aid of polymer-binding peptides ( Figure 22 ) [ 167 ]. Ferritin proteins obtained from the archaeon Archaeoglobus fulgidus have sufficiently high thermal stability.…”

Section: Nanoarchitectonics With Proteinsmentioning

confidence: 99%

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Biomimetic and Biological Nanoarchitectonics

Ariga

2022

IJMS

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A post-nanotechnology concept has been assigned to an emerging concept, nanoarchitectonics. Nanoarchitectonics aims to establish a discipline in which functional materials are fabricated from nano-scale components such as atoms, molecules, and nanomaterials using various techniques. Nanoarchitectonics opens ways to form a more unified paradigm by integrating nanotechnology with organic chemistry, supramolecular chemistry, material chemistry, microfabrication technology, and biotechnology. On the other hand, biological systems consist of rational organization of constituent molecules. Their structures have highly asymmetric and hierarchical features that allow for chained functional coordination, signal amplification, and vector-like energy and signal flow. The process of nanoarchitectonics is based on the premise of combining several different processes, which makes it easier to obtain a hierarchical structure. Therefore, nanoarchitectonics is a more suitable methodology for creating highly functional systems based on structural asymmetry and hierarchy like biosystems. The creation of functional materials by nanoarchitectonics is somewhat similar to the creation of functional systems in biological systems. It can be said that the goal of nanoarchitectonics is to create highly functional systems similar to those found in biological systems. This review article summarizes the synthesis of biomimetic and biological molecules and their functional structure formation from various viewpoints, from the molecular level to the cellular level. Several recent examples are arranged and categorized to illustrate such a trend with sections of (i) synthetic nanoarchitectonics for bio-related units, (ii) self-assembly nanoarchitectonics with bio-related units, (iii) nanoarchitectonics with nucleic acids, (iv) nanoarchitectonics with peptides, (v) nanoarchitectonics with proteins, and (vi) bio-related nanoarchitectonics in conjugation with materials.

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Section: Nanoarchitectonics With Proteinsmentioning

confidence: 99%

“… Complexes of ferritin and thermo-responsive polymer (poly(N-isopropylacrylamide)) formed with the aid of polymer-binding peptides. Reprinted with permission from Reference [ 167 ]. Copyright 2020 Chemical Society of Japan.…”

Section: Figurementioning

confidence: 99%

Biomimetic and Biological Nanoarchitectonics

Ariga

2022

IJMS

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“…A typical polymerization in the presence of virus initiator is shown in Figure b. − At first, a tertiary bromide was installed in Qβ virus by reaction of amino groups with N -hydroxysuccinimide followed by click reaction. As expected in comparison with unmodified Qβ, poly(OEGMA)-Qβ showed a decrease in retention volume in SEC and indicated an increase in hydrodynamic radius in dynamic light scattering (DLS) .…”

Section: Modifications Of Virusmentioning

confidence: 99%

Virus-Based Supramolecular Structure and Materials: Concept and Prospects

Hou

Jiang

et al. 2021

ACS Appl. Bio Mater.

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Rodlike and spherelike viruses are various monodisperse nanoparticles that can display small molecules or polymers with unique distribution following chemical modifications. Because of the monodisperse property, aggregates in synthetic protein−polymer nanoparticles could be eliminated, thus improving the probability for application in protein−polymer drug. In addition, the monodisperse virus could direct the growth of metal materials or inorganic materials, finding applications in hydrogel, drug delivery, and optoelectronic and catalysis materials. Benefiting from the advantages, the virus or viruslike particles have been widely explored in the field of supramolecular chemistry. In this review, we describe the modification and application of virus and viruslike particles in surpramolecular structures and biomedical research.

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“…The other biomolecular units were also used to create functional structural units as seen in the preparation of robust gels through assembly of cello-oligosaccharide networks [ 99 ] and fabrication of nanotubes with well-controlled diameters with sugar-featured lipid molecules [ 100 ]. Proteins are used as nanoarchitectonic units for formation of various structures thermo-controllable composite structures of ferritin and poly( N -isopropylacrylamide) [ 101 ] and glycosylated artificial metalloenzymes [ 102 ]. Nano-confined environments formed with ferritin cages can be utilized as reactors for controlled metal cluster nanoparticles [ 103 ].…”

Section: Introductionmentioning

confidence: 99%

Regulation of stem cell fate and function by using bioactive materials with nanoarchitectonics for regenerative medicine

Shi

et al. 2022

Science and Technology of Advanced Materials

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Nanoarchitectonics has emerged as a post-nanotechnology concept. As one of the applications of nanoarchitectonics, this review paper discusses the control of stem cell fate and function as an important issue. For hybrid nanoarchitectonics involving living cells, it is crucial to understand how biomaterials and their nanoarchitected structures regulate behaviours and fates of stem cells. In this review, biomaterials for the regulation of stem cell fate are firstly discussed. Besides multipotent differentiation, immunomodulation is an important biological function of mesenchymal stem cells (MSCs). MSCs can modulate immune cells to treat multiple immune- and inflammation-mediated diseases. The following sections summarize the recent advances of the regulation of the immunomodulatory functions of MSCs by biophysical signals. In the third part, we discussed how biomaterials direct the self-organization of pluripotent stem cells for organoid. Bioactive materials are constructed which mimic the biophysical cues of in vivo microenvironment such as elasticity, viscoelasticity, biodegradation, fluidity, topography, cell geometry, and etc. Stem cells interpret these biophysical cues by different cytoskeletal forces. The different cytoskeletal forces lead to substantial transcription and protein expression, which affect stem cell fate and function. Regulations of stem cells could not be utilized only for tissue repair and regenerative medicine but also potentially for production of advanced materials systems. Materials nanoarchitectonics with integration of stem cells and related biological substances would have high impacts in science and technology of advanced materials.

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Preparation and Dynamic Behavior of Protein-Polymer Complexes Formed with Polymer-Binding Peptides

Cited by 6 publications

References 28 publications

Biomimetic and Biological Nanoarchitectonics

Biomimetic and Biological Nanoarchitectonics

Virus-Based Supramolecular Structure and Materials: Concept and Prospects

Regulation of stem cell fate and function by using bioactive materials with nanoarchitectonics for regenerative medicine

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