Preparation and evaluation of PLGA-PEG/Gusperimus nanoparticles as a controlled delivery anti-inflammatory drug

Evaluation of Hyperthermic Potential and Acute Toxicity of PLGA‐PEG/Magnetite Microspheres Loaded with Oxaliplatin Using Mice as a Test System

“…The band placed at 1583 cm −1 refers to the vibrational stretch of the C=O bond, while the NH bond can be observed at 1516 cm −1 , the stretch of the CN bond is seen at ≈1423 cm −1 and the CO bond can be observed at 1138 cm −1 . [ 45–47 ]…”

“…The band placed at 1583 cm −1 refers to the vibrational stretch of the C=O bond, while the NH bond can be observed at 1516 cm −1 , the stretch of the CN bond is seen at ≈1423 cm −1 and the CO bond can be observed at 1138 cm −1 . [45][46][47] The magnetite modification was also studied through thermogravimetric analyses and the obtained results are shown in Figure 8. The difference between weight losses up to 600 °C of magnetite and the modified product is equal to 13%, which can be associated with the presence of lysine.…”

Self-Assembled Aggregated Structures of Natural Products for Oral Drug Delivery

“…27 For encapsulation of hydrophilic drug, it is convenient to carry out functionalization of the PLGA nanoparticles with hydrophilic molecules such as polyethylene glycol (PEG) to potentiate the transport and drug release properties of this system. 28 Natural polysaccharide alginate has been widely utilized in the preparation of microcapsules along with high potential as Active Pharmaceutical Ingredient delivery carriers. 29 Zhang et al encapsulated methotrexate(MTX)-loaded human serum albumin nanoparticles into calcium alginate chitosan microcapsules, which could efficiently protect nanoparticles from degradation in gastric acid and protease to target accumulate in arthritic joints and intestinal inflammation lesions, while inhibiting the severe gastrointestinal toxicity caused by the oral administration of free MTX.…”

Preparation and Evaluation of PLGA-based Nanoparticles

“…These were then looked at with a scanning electron microscope. 38 PLGA based nanoparticles particle size characterization A laser particle size detector was used to find out the nanoparticles' particle size, size distribution, and polydispersity index after the right steps were taken to dilute them. 39 Zeta potential study of PLGA based nanoparticles Using a zeta sizer and U-shaped tube at 25°C, the electrophoretic mobility of the nanoparticles revealed their surface charge.…”