PREPARATION AND EVALUATION OF POROUS &amp;beta;-TCP BASED COMPOSITES BY GREEN PROCESS

The production of porous ceramics for biomedical applications is widely available in the Ceramics industry. In bioceramic applications, interconnected pores are pertinent to increase osteoconductivity and cell proliferation. However, an increase in pore size and the pore amount decrease the mechanical properties. For this reason, pore properties must be precisely controlled. In this study, the effect of a natural pore-forming agent, corn starch addition, and sintering conditions on mechanical properties and biocompatibility was investigated. During mixing, four different starch amounts (1, 3, 5, and 10 wt%) were added to pure beta-tricalcium phosphate (β-TCP) ceramic powders and pressed. Pressed pellets were sintered at 1000, 1100, 1200, and 1300 °C. A scanning electron microscope (SEM) is used to investigate microstructure, texture, pore size, and cell adhesion. The mechanical properties of the β-TCP ceramic parts were further characterized by measuring the density and compressive strength. Cytotoxicity tests were carried out with MTT assays. The optimum mechanical properties were obtained at 1100 °C sintered biocomposites. Although starch starts to burn around 410 °C and analytical results show no presence of starch after the sintering process, biocomposites initially containing 10% starch showed improved cell proliferation. However, a reduction of 59% in compressive strength and a 16% reduction in the density were also recorded. It was observed that 10 wt% starch addition increases cell proliferation by 10% in sintered β-TCP samples. Starch powder additions can be used to increase the cell viability of the material by facilitating the creation of pores, as a low-cost pore-forming agent for porous bone graft and non-load-bearing material in both orthopaedics and maxillofacial applications.

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Synthesis and cytotoxicity analysis of porous β-TCP/starch bioceramics

Turan

Kalkandelen

Palacı

et al. 2022

J Aust Ceram Soc

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Syntheses and Evaluation of Porous ZrO<sub>2</sub> Ceramics by Electrophoretic Deposition Method

Nakahira

Ishihara

Nakamura

2007

J. Ceram. Soc. Japan

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In this study, porous ZrO 2 ceramics were successfully prepared by an electrophoretic depositions EPD method with gas generation in the aqueous ZrO 2 slurry. Especially, this aqueous EPD process in combination with a sintering step formed porous ZrO 2 with a number of unidirectionally aligned continuous pores. Also, adding starch into ZrO 2 slurry resulted in the increase of porosity of ZrO 2 ceramics. Thus, applying the aqueous EPD process has a great advantage in environmental issues and cost reduction for fabricating porous ceramics.

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Synthesis and evaluation of porous hydroxyapatite prepared by hydrothermal treatment and subsequent sintering method

Nakamura

Nakahira

2008

J. Ceram. Soc. Japan

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Hydrothermal treatment and subsequent post sintering were used to fabricate porous and strong hydroxyapatite. Here, steam curing method was used as a hydrothermal treatment and subsequent post sintering treatment was done in air. As a result, samples prepared by steam curing and subsequent post sintering had higher porosity and compressive strength than those prepared by normal sintering process because of the structural changes introduced during steam curing and subsequent post sintering. Moreover, the effect of synthetic condition of these processes on the microstructure for porous hydroxyapatite was investigated.

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PREPARATION AND EVALUATION OF POROUS β-TCP BASED COMPOSITES BY GREEN PROCESS

Abstract: Abstract:The scaffolds composed of monolithic ƒÀ-TCP and ƒÀ-

Cited by 3 publications

References 11 publications

Synthesis and cytotoxicity analysis of porous β-TCP/starch bioceramics

Synthesis and cytotoxicity analysis of porous β-TCP/starch bioceramics

Syntheses and Evaluation of Porous ZrO<sub>2</sub> Ceramics by Electrophoretic Deposition Method

Synthesis and evaluation of porous hydroxyapatite prepared by hydrothermal treatment and subsequent sintering method

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