2021
DOI: 10.1002/ces2.10078
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Preparation and physical‐biological characterization on titanium doped fluorophosphate nanobioglass: Bone implants

Abstract: Metals, ceramics, natural or synthetic polymers, and their composites are used as biomaterials aiding the clinician in the repair. Among these, biomaterials in orthopedics have very many demanding characteristics like tunable density, elasticity, and strength near to that of bone, bioresorbability and the ability to bond to live bone and not being toxic to the cells. Hench and Clark paved the way for preparing bioglasses and it is named as 45S5 bioglass. The 45S5 bioglass promotes osteogenesis by

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Cited by 4 publications
(2 citation statements)
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“…Computational simulations complement our previous study on the interaction of a series of amino acids with a model rutile (110) surface [29] and support the experimental findings of a signifi-cant suppression of amino acids adsorption on rutile by Tris. Despite growing concerns regarding the reliability of Trisbuffered SBF solutions for in vitro testing of biomaterials, and the effort of various groups to present refined protocols [24], in vitro bioactivity tests are still very commonly performed using Tris [30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51]. Our results highlight and quantify the so-far mostly overlooked role of Tris and should motivate the scientific community to establish in vitro testing protocols that are free of Tris-induced artefacts.…”
Section: Introductionmentioning
confidence: 80%
“…Computational simulations complement our previous study on the interaction of a series of amino acids with a model rutile (110) surface [29] and support the experimental findings of a signifi-cant suppression of amino acids adsorption on rutile by Tris. Despite growing concerns regarding the reliability of Trisbuffered SBF solutions for in vitro testing of biomaterials, and the effort of various groups to present refined protocols [24], in vitro bioactivity tests are still very commonly performed using Tris [30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51]. Our results highlight and quantify the so-far mostly overlooked role of Tris and should motivate the scientific community to establish in vitro testing protocols that are free of Tris-induced artefacts.…”
Section: Introductionmentioning
confidence: 80%
“…Yang et al, 2011. [Colour figure can be viewed at wileyonlinelibrary.com] engineered to release fluoride ions at a controlled rate, increasing proliferation and osteogenesis of MC3T3 cells in vitro (Borkowski et al, 2020). Similarly, titanium containing fluoride-doped phosphate nanobioglasses enhanced osteogenesis in vitro resulting in higher amounts of bone formation in vivo (Sankaralingam et al, 2021).…”
Section: Scaffold Dopantsmentioning
confidence: 99%