Preparation, characterization and evaluation of biocomposite films containing chitosan and sago starch impregnated with silver nanoparticles

Arockianathan, P. Marie; Sekar, S.; Kumaran, B.; Sastry, T. P.

doi:10.1016/j.ijbiomac.2012.02.022

Cited by 85 publications

(30 citation statements)

References 42 publications

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“…162 Marie Arockionananthan and colleagues reported the wound healing ability of chitosan/sargo starch/silver nanoparticles on male albino Wistar rats in 16 days. 163 Around 5-500 mg/mL of chitosan/montmorillonite nanocomposite powder was found to be cytocompatible to Caco-2 cells and was found to effectively stimulate cell proliferation. However, high concentration of clay mineral as such could block most of the channels on cell membrane causing cell death.…”

Section: Biocompatibility and Concentration Dependent Toxicitymentioning

confidence: 99%

Natural Polymer/Inorganic Material Based Hybrid Scaffolds for Skin Wound Healing

et al. 2015

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Dermal tissue engineering focuses on the restoration of diseased and damaged tissues by using a combination of cells, biomaterials, and bioactive molecules. Inorganic substances like zeolites, clay, mesoporous silica, metals, and metal oxides are advanced materials used in wound healing research. They can improve the structural stability and bioactivity of bio polymeric scaffolds. Zeolites, clays, and mesoporous silica act as suitable carriers for drug delivery and when incorporated within scaffolds, serve as ideal matrices for promoting skin regeneration. This review focuses on various natural polymers/inorganic materials based composite scaffolds used for skin tissue engineering, highlighting their synthesis routes and mode of action by which wound healing is enhanced. Among the different inorganic materials used, the role of zeolites incorporated biocomposites for promoting blood coagulation, antibacterial effect; oxygen delivery to cells and wound healing are discussed in detail. The article thus includes recent attempts to explore the hidden potential of inorganic materials in dermal tissue engineering.

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Section: Biocompatibility and Concentration Dependent Toxicitymentioning

confidence: 99%

Natural Polymer/Inorganic Material Based Hybrid Scaffolds for Skin Wound Healing

et al. 2015

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“…The wound healing rates were 98.98 ± 6.09%, 81.67 ± 6.30% and healing time was13.51 ± 4.56 days and 17.45 ± 6.23 days for silver nanocrystalline chitosan dressing dressing treated group and silver sulfadiazine dressing treated control groups respectively. Arockianathan et al [53] prepared composite films with chitosan, sago starch and silver nanoparticles with and without antibiotic gentamicin (G) by solvent casting method. Complete healing time for control, chitosan-sago-silver nanoparticles and chitosan-sago-silver nanoparticles with gentamicin were 24, 18 and 16 days respectively.…”

Section: Wound Closure Ratementioning

confidence: 99%

Chitosan-PVP-nano silver oxide wound dressing: In vitro and in vivo evaluation

Archana

Singh

Dutta

et al. 2015

International Journal of Biological Macromolecules

328

134

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“…Arockianathan et al [135] prepared composite films with CS, sago starch, silver nanoparticles, and gentamycin. To see the effect of gentamycin some films were without it.…”

Section: Wound Dressings With Chitosan and Nanoparticlesmentioning

confidence: 99%

Chitosan: A Potential Therapeutic Dressing Material for Wound Healing

Archana

Dutta

2015

Springer Series on Polymer and Composite Materials

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A wide variety of polymers have been used over decades for the preparation of dressing materials for wound healing applications. But the dressing materials based on polysaccharides such as chitosan (CS) have received tremendous attention of the worldwide researchers as a consequence of its important properties like anti-infectional activity, biocompatibility, biodegradability, nontoxicity to mention a few. CS helps in every phase of wound healing such as acting as barrier against microbes, absorbing exudates, accelerates the infiltration of inflammatory cells like neutrophils and helps in healing without scar formation. A reason behind the popularity of CS is that not only it can easily be processed as gels, films, fibers, and scaffolds but also can be blended with natural as well as synthetic polymers to reduce price and improve properties like mechanical, wettability, gas permeability, and handling. Apart from natural and synthetic polymers, CS is also blended with nanoparticles and growth factors to which it shows better antibacterial activity and reduce time span for wound healing. The present chapter aims to focus on feasibility of combining natural polymers, synthetic polymers, nanoparticles, and growth factors with CS for the preparation of wound dressings as basic healthcare materials for regenerative medicine.

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Preparation, characterization and evaluation of biocomposite films containing chitosan and sago starch impregnated with silver nanoparticles

Cited by 85 publications

References 42 publications

Natural Polymer/Inorganic Material Based Hybrid Scaffolds for Skin Wound Healing

Natural Polymer/Inorganic Material Based Hybrid Scaffolds for Skin Wound Healing

Chitosan-PVP-nano silver oxide wound dressing: In vitro and in vivo evaluation

Chitosan: A Potential Therapeutic Dressing Material for Wound Healing

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