Preparation, characterization of Electrospun Polycaprolactone-nano Zinc oxide composite scaffolds for Osteogenic applications

Harikrishnan, Pandurangan; Sivasamy, A.

doi:10.1016/j.nanoso.2020.100518

Cited by 35 publications

(23 citation statements)

References 19 publications

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“…Recent studies reveal the design of a self‐powered electrospinning system, which will further enhance the feasibility of electrospinning 10,11 . Electrospun polymer nanofibers find a wide variety of applications in various areas like tissue engineering, biomedical, water purification, energy conservation, environmental safety, catalytic processes, electronics, solar cells etc., as evidenced in the referred literatures 12–23 …”

Section: Introductionmentioning

confidence: 79%

Structurally modified poly(methyl methacrylate) electrospun nanofibers as better host matrix for noble metal nanoparticles

Philip

Jose

Parameswaran

et al. 2020

J of Applied Polymer Sci

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Poly(methyl methacrylate) (PMMA) nanofibers are proved as good host matrix for various nanomaterials. Here, the possibilities offered by the process of electrospinning are exploited for the production of pure and structurally modified surface roughened and coaxial hollow PMMA electrospun nanofibers with unique advantages and surface characteristics, which is proved through various structural analyses. The host matrix nature of these pure and structurally modified surface roughened and coaxial hollow PMMA nanofibers to gold nanoparticles (AuNPs) are proved through different structural and morphological analyses. The host matrix nature of pure and structurally modified surface roughened and coaxial hollow PMMA nanofibers to AuNPs are compared with that of pure PMMA nanofibers by comparing their structural and optical properties. It is found here that, the surface roughened PMMA nanofibers act as better host matrix with more uniform distribution of particles and intensity enhancement than the pure and coaxial hollow PMMA nanofibers. Pure and coaxial hollow PMMA nanofibers show almost two times enhancement in intensity while the surface roughened PMMA nanofibers show almost five times enhancement in intensity after incorporating AuNPs. The host matrix nature of PMMA nanofibers is thus proved to be improved by making structural modifications on PMMA nanofibers in a simple and cost‐effective way. This makes them more suitable and adaptable in their applications. This superior property of surface roughened PMMA nanofibers over pure PMMA nanofibers can be used in all the application fields of PMMA nanofibers like optical works, catalytically supporting agents, antibacterial supporting systems and so on.

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Section: Introductionmentioning

confidence: 79%

Structurally modified poly(methyl methacrylate) electrospun nanofibers as better host matrix for noble metal nanoparticles

Philip

Jose

Parameswaran

et al. 2020

J of Applied Polymer Sci

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“…It can be degraded by the hydrolysis process under physiological conditions, but the rate of degradation is slower due to the presence of repeating five hydrophobic CH 2 moieties [108]. Polycaprolactone is an FDA-approved biodegradable polymer used in bone tissue engineering and the addition of biocompatible nanoparticles significantly overcomes the bioactivity issues related to polycaprolactone [109]. The polycaprolactone-based hybrid scaffold has shown cytocompatibility in SaoS-2 cells with enhanced cell viability and cell density compared to the control.…”

Section: Synthetic Polymer-based Biomaterialsmentioning

confidence: 99%

Advancement of Nanobiomaterials to Deliver Natural Compounds for Tissue Engineering Applications

Kumar

Abrahamse

2020

IJMS

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Recent advancement in nanotechnology has provided a wide range of benefits in the biological sciences, especially in the field of tissue engineering and wound healing. Nanotechnology provides an easy process for designing nanocarrier-based biomaterials for the purpose and specific needs of tissue engineering applications. Naturally available medicinal compounds have unique clinical benefits, which can be incorporated into nanobiomaterials and enhance their applications in tissue engineering. The choice of using natural compounds in tissue engineering improves treatment modalities and can deal with side effects associated with synthetic drugs. In this review article, we focus on advances in the use of nanobiomaterials to deliver naturally available medicinal compounds for tissue engineering application, including the types of biomaterials, the potential role of nanocarriers, and the various effects of naturally available medicinal compounds incorporated scaffolds in tissue engineering.

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“…Electrospinning can be used to produce polymer nanofibers in pure as well as in other forms like blend, coaxial, hollow, porous, and so on 22 . Thus, the applications of electrospun polymer nanofibers can be increased by modifying their properties 23–32 …”

Section: Introductionmentioning

confidence: 99%

“…22 Thus, the applications of electrospun polymer nanofibers can be increased by modifying their properties. [23][24][25][26][27][28][29][30][31][32] Here, pure and structurally modified surface roughened and coaxial hollow PMMA nanofibers are produced by electrospinning. The preparation of pure and structurally modified PMMA nanofibers is described in detail in our previously published paper.…”

mentioning

confidence: 99%

Structurally modified electrospun poly(methyl methacrylate) nanofibers as advanced host matrices for PbS quantum dots

Philip

Jose

Vanchippurackal

2021

J of Applied Polymer Sci

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The present work deals with the studies of the host matrix nature of pure and structurally modified surface roughened and coaxial hollow electrospun poly(methyl methacrylate) (PMMA) nanofibers to lead sulphide (PbS) quantum dots. The various structural and molecular analyses conducted on these samples proved the advancements and structural modifications made in the properties of pure PMMA nanofibers by electrospinning and selective dissolution. The successful incorporation of the quantum dots to pure and structurally modified PMMA nanofibers and hence the host matrix nature of these nanofibers is proved by different spectral analyses of the samples. The coaxial hollow PMMA nanofibers are found to be the best host matrix among these PMMA nanofibers as proved by the optical studies of the samples. Photoluminescence analyses of the samples showed the influence of these quantum dots on the optical properties of PMMA nanofibers. It is observed here that, the quantum dots enhance the intensity of coaxial hollow PMMA nanofibers to about four times than its virgin form. The pure and structurally modified PMMA nanofibers incorporated with PbS quantum dots are proved to be efficient for the degradation of methylene blue dye where coaxial hollow PMMA nanofibers incorporated with PbS quantum dots is the best.

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Preparation, characterization of Electrospun Polycaprolactone-nano Zinc oxide composite scaffolds for Osteogenic applications

Cited by 35 publications

References 19 publications

Structurally modified poly(methyl methacrylate) electrospun nanofibers as better host matrix for noble metal nanoparticles

Structurally modified poly(methyl methacrylate) electrospun nanofibers as better host matrix for noble metal nanoparticles

Advancement of Nanobiomaterials to Deliver Natural Compounds for Tissue Engineering Applications

Structurally modified electrospun poly(methyl methacrylate) nanofibers as advanced host matrices for PbS quantum dots

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