2022
DOI: 10.1007/s13399-022-02586-y
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Preparation of cellulose-PVA blended hydrogels for wound healing applications with controlled release of the antibacterial drug: an in vitro anticancer activity

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Cited by 13 publications
(7 citation statements)
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“…The C–O–C and C–OH stretching vibrations were identified at 1157 and 1028 cm –1 , respectively, with a broad peak at 3423 cm –1 attributable to the hydroxyl group (OH) stretching vibration, present in β-CD, cellulose, and PVA. These peaks confirmed the presence of β-CD, cellulose, and PVA in the hydrogels. , The absence of the 1028 cm –1 peak in the CP7C hydrogel indicated the lack of an β-CD. A reduced intensity of the 3423 cm –1 peak in the hydrogels, compared to pure β-CD and cellulose, suggests a decrease in hydroxyl groups and hydrogen bonding, resulting from the cross-linking reaction between ECH and the hydroxyl groups of β-CD, cellulose, and PVA. , After the adsorption of malathion (MT), the sample was labeled CP1C-MT, as depicted in Figure b.…”
Section: Resultsmentioning
confidence: 61%
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“…The C–O–C and C–OH stretching vibrations were identified at 1157 and 1028 cm –1 , respectively, with a broad peak at 3423 cm –1 attributable to the hydroxyl group (OH) stretching vibration, present in β-CD, cellulose, and PVA. These peaks confirmed the presence of β-CD, cellulose, and PVA in the hydrogels. , The absence of the 1028 cm –1 peak in the CP7C hydrogel indicated the lack of an β-CD. A reduced intensity of the 3423 cm –1 peak in the hydrogels, compared to pure β-CD and cellulose, suggests a decrease in hydroxyl groups and hydrogen bonding, resulting from the cross-linking reaction between ECH and the hydroxyl groups of β-CD, cellulose, and PVA. , After the adsorption of malathion (MT), the sample was labeled CP1C-MT, as depicted in Figure b.…”
Section: Resultsmentioning
confidence: 61%
“…Initially, each sample underwent dehydration using a graded ethanol solution. Dehydration involved immersing the samples in ethanol solutions of varying concentrations (30,50,60,80,95, and 99.8%) for 30 min at each step. 62 Subsequently, the samples were lyophilized by using a freeze-dryer (Harvest Right, HRFD-P-M-SS, Salt Lake City, UT) at −40 °C and 0.67 mbar for 24 h. Following lyophilization, the samples were crushed into fine powder by using a mortar and pestle, then coated with platinum, and examined using SEM at 5000× magnification, with an accelerating voltage of 1.0 kV.…”
Section: Methodsmentioning
confidence: 99%
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“…As shown in Figure S2, the characteristic absorption peaks at 3446 and 1651 cm -1 attributed to O-H and N-H, respectively. C=O stretching is shifted to lower frequencies in the composite hydrogel, indicating strong hydrogen bonding [60][61] . To investigate phase composition in the composite hydrogel, XRD is used to test samples with or without freeze-thaw treatment.…”
Section: Synthesis and Characterizations Of Pcp Hydrogelmentioning
confidence: 99%
“…This network structure of hydrogels makes them a frequently employed method, especially in the medical eld where a controlled release is required (Costa-Júnior 2002; Davis and Anseth 2002). It has been reported that polyvinyl alcohol is frequently preferred in hydrogel applications due to its properties such as ease of synthesis, low toxicity, easy control of product quality and low cost (Xiao et al 2022;Sankarganesh et al 2022 ) and PVA/NaCMC hydrogels are frequently used as they are non-cytotoxic and have high biocompatibility (Shin et al 2018) Hydrogels release actively with extrinsic factors such as temperature, pH, electrical eld, and radiation and can be used in functional product (Hosseinkhani et al 2006).…”
Section: Introductionmentioning
confidence: 99%