Preparation of graphene oxide/polyacrylamide composite hydrogel and its effect on Schwann cells attachment and proliferation

Graphene Oxide/Polymer‐Based Biomaterials

“…1.2% GO/polyacrylamide hydrogel for peripheral nerve regeneration (tension) [46] 38 MPa N/A N/A Skin [152] 1-30 MPa 15-150 MPa 30-115 1 wt% GO/PVA for load-bearing tissue substitutes (compression) [135] 17 MPa 60 kPa N/A 0.1 wt% GO/PVA (compression) [38] 2.8 MPa N/A N/A 1 wt% GO/cellulose/PVA (tension) [39] 0.73 MPa N/A 240 1 mg ml À1 GO/carboxymethyl chitosan/KGM for wound dressing (compression) [48] 208 kPa 1.11 MPa N/A GO/polyacrylamide/agar (compression) [122] 332 kPa N/A 4600 2 mg ml À1 GO/GelMa hydrogel for cardiac patches (tension) [47] 977 kPa 24 kPa 55 1 mg ml À1 GO/gelatin hydrogel for muscle tissue engineering (rheometry measurement) [102] N/A 3.42 kPa N/A www.advancedsciencenews.com www.aem-journal.com engineering applications. The incorporation of GO in polymer was found to improve the physical and biological properties of the composites.…”

“…0.2-1.2 mg ml À1 GO/ PAM [46] Hydrogel by in situ radical polymerization Schwann cells 0.4 mg ml À1 GO led to highest cell attachment and proliferation 0.5-1 mg ml À1 GO/ Hydrogel by UV NIH3T3 GO enhanced 3D cell spreading and proliferation. GO also improved electrical and mechanical (Continued) interaction was evident from XPS results which showed an increase of protonated amines from 7.1 to 11.3% with the addition of 1 wt% GO in chitosan.…”

“…GO/polyacrylamide hydrogels were also developed by Li et al [46] to study its effect on Schwann cell attachment and proliferation. The addition of 0.4 mg ml À1 GO led to optimum Schwann cell attachment and proliferation.…”

“…Polyacrylamide hydrogels are biocompatible, soft, and can easily be processed, therefore they are extensively studied in the field of tissue engineering. [46] Polyacrylamide Hydrogels Zhang et al [136] prepared GO/sodium alginate/polyacrylamide hydrogels. Alginate was incorporated to induce pH sensitivity in the hydrogels and to promote its mechanical properties.…”

Recent Progress of Graphene‐Containing Polymer Hydrogels: Preparations, Properties, and Applications

“…MBA is the most used chemical cross‐linker. For example, Yang and co‐workers fabricated PAM–GO hydrogel as shown in Figure . AM and MBA were first dissolved into water and then GO dispersion was added into the solution.…”