Preparation of hydroxyapatite-containing titania coating on titanium substrate by micro-arc oxidation

Ni, Jiahua; Shi, Yifeng; Yan, Fang; Chen, Jianzhi; Wang, Lei

doi:10.1016/j.materresbull.2007.02.019

Cited by 40 publications

(26 citation statements)

References 14 publications

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“… 1 The relevance of HAP in load-bearing implants is constrained because of the typical fragility with small fracture toughness. 2 Generally, HAP can be combined with different varieties of natural polymers, synthetic polymers, and graphene family materials. 3 …”

Section: Introductionmentioning

confidence: 99%

Cisplatin-Loaded Graphene Oxide/Chitosan/Hydroxyapatite Composite as a Promising Tool for Osteosarcoma-Affected Bone Regeneration

et al. 2018

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Presently, tissue engineering approaches have been focused toward finding new potential scaffolds with osteoconductivity on bone-disease-affected cells. This work focused on the cisplatin (CDDP)-loaded graphene oxide (GO)/hydroxyapatite (HAP)/chitosan (CS) composite for enhancing the growth of osteoblast cells and prevent the development of osteosarcoma cells. The prepared composites were characterized for the confirmation of composite formation using Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, and X-ray diffraction techniques. A flowerlike morphology was observed for the GO/HAP/CS-3/CDDP composite. UV–vis spectroscopy was used to observe the controlled release of CDDP from the GO/HAP/CS-3/CDDP composite, and 67.34% of CDDP was released from the composite over a time period of 10 days. The GO/HAP/CS-3/CDDP nanocomposites showed higher viability in comparison with GO/HAP/CS-3 on MG63 osteoblast-like cells and higher cytotoxicity against cancer cells (A549). The synthesized composite was found to show enhanced proliferative, adhesive, and osteoinductive effects on the alkaline phosphatase activity of osteoblast-like cells. Our results suggested that the CDDP-loaded GO/HAP/CS-3 nanocomposite has an immense prospective as a bone tissue replacement in the bone-cancer-affected tissues.

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Section: Introductionmentioning

confidence: 99%

Cisplatin-Loaded Graphene Oxide/Chitosan/Hydroxyapatite Composite as a Promising Tool for Osteosarcoma-Affected Bone Regeneration

et al. 2018

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“…Cross-sectional images ( Figure 9) also indicated that highly-ordered nano-channels were perpendicular to the substrate, and a compact layer can be observed between the nanopore arrays and the substrate. Besides, the addition of PO 3− 4 in the electrolyte further improved the cellular performance [92,93]. Moreover, A well-defined micro-/nano-morphology can also be acquired by this HCA technique in electrolytes, such as Cu(NO 3 ) 2 , Zn(NO 3 ) 2 , (Na 3 PO 4 + Ca(NO 3 ) 2 + Na 2 SiO 3 ) and (Na 3 PO 4 + AgNO 3 + Na 2 SiO 3 ), which will extend its application.…”

Section: Introduction Of Metallic Compounds Into Mao Electrolytementioning

confidence: 99%

Review of Antibacterial Activity of Titanium-Based Implants’ Surfaces Fabricated by Micro-Arc Oxidation

Zhang

Wang

et al. 2017

Coatings

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Ti and its alloys are the most commonly-used materials for biomedical applications. However, bacterial infection after implant placement is still one of the significant rising complications. Therefore, the application of the antimicrobial agents into implant surfaces to prevent implant-associated infection has attracted much attention. Scientific papers have shown that inorganic antibacterial metal elements (e.g., Ag, Cu, Zn) can be introduced into implant surfaces with the addition of metal nanoparticles or metallic compounds into an electrolyte via micro-arc oxidation (MAO) technology. In this review, the effects of the composition and concentration of electrolyte and process parameters (e.g., voltage, current density, oxidation time) on the morphological characteristics (e.g., surface morphology, bonding strength), antibacterial ability and biocompatibility of MAO antimicrobial coatings are discussed in detail. Anti-infection and osseointegration can be simultaneously accomplished with the selection of the proper antibacterial elements and operating parameters. Besides, MAO assisted by magnetron sputtering (MS) to endow Ti-based implant materials with superior antibacterial ability and biocompatibility is also discussed. Finally, the development trend of MAO technology in the future is forecasted.

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“…Cross-sectional images (Fig.9) also indicated that highly-ordered nano-channels were perpendicular to the substrate, and a compact layer can be observed between the nanopore arrays and the substrate. Besides, the addition of PO4 3-in the electrolyte further improved the cellular performance [92,93]. Moreover, A well-defined micro/nano-morphology can also be acquired by this HCA technique in electrolyte such as Cu(NO3)2, Zn(NO3)2, (Na3PO4 + Ca(NO3)2 + Na2SiO3), and (Na3PO4 + AgNO3 + Na2SiO3), which will extend its application.…”

Section: Introduction Of Metallic Compounds Into Mao Electrolytementioning

confidence: 86%

Review of Antibacterial Activity of Titanium-based Implants Surfaces Fabricated by Micro-arc Oxidation

He¹,

Zhang²,

Wang³

et al. 2017

Preprint

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Ti and its alloys are the most commonly used materials for biomedical applications. However, bacterial infection after implant placement is still one of the significant rising complications. Therefore, the application of the antimicrobial agents into implant surfaces to prevent implant-associated infection has attracted lots of attentions. Scientific papers have shown that inorganic antibacterial metal elements (e.g. Ag, Cu, Zn) can be introduced into implant surfaces with the addition of metal nanoparticles or metallic compounds into electrolyte via micro-arc oxidation (MAO) technology. In this review, the effects of the composition and concentration of electrolyte and process parameters (e.g. voltage, current density, oxidation time) on morphological characteristics (e.g. surface morphology, bonding strength), antibacterial ability and biocompatibility of MAO antimicrobial coatings were discussed in detail. Anti-infection and osseointegration can be simultaneously accomplished with the selection of the proper antibacterial elements and operating parameters. Besides, MAO assisted by magnetron sputtering (MS) to endow Ti-based implant materials with superior antibacterial ability and biocompatibility was also discussed. Finally, the development trend of MAO technology in the future was forecasted.

show abstract

Preparation of hydroxyapatite-containing titania coating on titanium substrate by micro-arc oxidation

Cited by 40 publications

References 14 publications

Cisplatin-Loaded Graphene Oxide/Chitosan/Hydroxyapatite Composite as a Promising Tool for Osteosarcoma-Affected Bone Regeneration

Cisplatin-Loaded Graphene Oxide/Chitosan/Hydroxyapatite Composite as a Promising Tool for Osteosarcoma-Affected Bone Regeneration

Review of Antibacterial Activity of Titanium-Based Implants’ Surfaces Fabricated by Micro-Arc Oxidation

Review of Antibacterial Activity of Titanium-based Implants Surfaces Fabricated by Micro-arc Oxidation

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