Preparation of mixed matrix adsorber membranes for protein recovery

Avramescu, M.E.; Girones, M.; Borneman, Zandrie; Weßling, Matthias

doi:10.1016/s0376-7388(03)00178-9

Cited by 104 publications

(85 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Membrane adsorbent technology is a membrane integration technology that was developed in the mid-1980s (Avramescu et al 2003(Avramescu et al , 2008. Adsorption is a mass transfer process by which a substance is transferred from the liquid phase to the surface of a solid, and becomes bound by physical and/or chemical interactions.…”

Section: General Theory Of Metals Adsorption On Membrane Surfacementioning

confidence: 99%

Removal of heavy metals and pollutants by membrane adsorption techniques

2018

View full text Add to dashboard Cite

Application of polymeric membranes for the adsorption of hazardous pollutants may lead to the development of next-generation reusable and portable water purification appliances. Membranes for membrane adsorption (MA) have the dual function of membrane filtration and adsorption to be very effective to remove trace amounts of pollutants such as cationic heavy metals, anionic phosphates and nitrates. In this review article, recent progresses in the development of MA membranes are surveyed. In addition, recent progresses in the development of advanced adsorbents such as nanoparticles are summarized, since they are potentially useful as fillers in the host membrane to enhance its performance. The future directions of R&D in this field are also shown in the conclusion section.

show abstract

Section: General Theory Of Metals Adsorption On Membrane Surfacementioning

confidence: 99%

Removal of heavy metals and pollutants by membrane adsorption techniques

2018

View full text Add to dashboard Cite

show abstract

“…The concept is quite simple and it is easy to prepare such mixed matrix membranes while still giving a performance that is competitive with current chromatographic membranes. Wessling et al prepared MMM adsorbers using an ethylene vinyl alcohol (EVAL) base membrane with several types of lewatit cation and anion exchange resins and successfully applied these to the separation of bovine serum albumin (BSA), lysozyme and bilirubin (Avramescu et al, 2003b(Avramescu et al, , 2004Saiful et al, 2006). Although this type of ion exchange MMM adsorber was first reported in 2003, little attention has been given to it for industrial applications.…”

Section: Introductionmentioning

confidence: 99%

Fractionation of β‐Lactoglobulin from whey by mixed matrix membrane ion exchange chromatography

Saufi

Fee

2009

Biotech & Bioengineering

View full text Add to dashboard Cite

Mixed matrix membranes (MMMs), which incorporate adsorptive particles during membrane casting, can be prepared simply and have performances that are competitive with other membrane chromatography materials. The application of MMM chromatography for fractionation of beta-Lactoglobulin from bovine whey is described in this article. MMM chromatography was prepared using ethylene vinyl alcohol polymer and lewatit anion exchange resin to form a flat sheet membrane. The membrane was characterized in terms of structure and its static and dynamic binding capacities were measured. The optimum binding for beta-Lactoglobulin was found to be at pH 6.0 using 20 mM sodium phosphate buffer. The MMM had a static binding capacity of 120 mg/g membrane (36 mg/mL membrane) and 90 mg/g membrane (27 mg/mL membrane) for beta-Lactoglobulin and alpha-Lactalbumin, respectively. In batch fractionation of whey, the MMM showed selective binding towards beta-Lactoglobulin compared to other proteins. The dynamic binding capacity of beta-Lactoglobulin in whey solution was about 80 mg/g membrane (24 mg beta-Lac/mL of MMM), which is promising for whey fractionation using this technology. This is the first reported application of MMM chromatography to a dairy feed stream.

show abstract

“…Therefore, it is highly desirable to provide an alternate cost-effective nanomembrane in a position above the trade-off curves between permeability and selectivity [19]. Mixed-matrix membranes (MMMs) are considered as hybrid membranes containing liquid, solid, or both liquid and solid fillers embedded in a polymer matrix [28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45]. They are densely packed polymer membranes with organic or inorganic nanoparticles introduced into their structure.…”

Section: Concept Of Mixed-matrix Nanomembranesmentioning

confidence: 99%