“…SCW can also break down covalent bonds such as ester, ether, and peptide bonds, making it advantageous for the extraction of useful materials (Kus, 2012). By using SCW, materials maintaining physiological activity can be extracted from sources such as watermelons (Kim et al, 2014a), oyster mushrooms (Jo et al, 2013), blue mussel (Han et al, 2018), and Styela clava (Jo et al, 2018). Therefore, in this study, we present the possibility of applying SCW to PBL by manufacturing the extract under three different temperatures and analyzing the physiological activity of alcohol metabolizing enzymatic activity, angiotensin converting enzyme (ACE) inhibition, and tyrosinase inhibition.…”