Preparation of the micro/nano structures of the biomimetic coating stent for loading MiRNA126 by four-beam laser interference

Wang, Junnan; Li, Yongliang; Gao, Longyue; Wang, Siqi; Mao, Aofei; Liu, Bin

doi:10.1016/j.ijleo.2016.10.030

Cited by 15 publications

(7 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results found that parallel grooves on the surface significantly increased the migration rate of endothelial cells. Wang et al [76] produced microstructures with different periods on the surface of metallic vascular stents and loaded the mixture of polymer and drug into the microstructures. The results showed that the microstructure with a period of 10 µm had the best drug adhesion and releasing properties.…”

Section: Microstructuresmentioning

confidence: 99%

“…Each processing method has its advantages and disadvantages. After stent processing, a series of post-processing techniques, including drug coating [65][66][67][68][69][70], surface modification [71][72][73][74], surface microstructures [75][76][77][78][79] can significantly improve the surface quality and the biocompatibility of the stent. Therefore, the efficacy and safety of vascular stents largely depend on precision manufacturing technology and post-processing technology.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Review on Manufacturing and Post-Processing Technology of Vascular Stents

et al. 2022

View full text Add to dashboard Cite

Percutaneous coronary intervention (PCI) with stent implantation is one of the most effective treatments for cardiovascular diseases (CVDs). However, there are still many complications after stent implantation. As a medical device with a complex structure and small size, the manufacture and post-processing technology greatly impact the mechanical and medical performances of stents. In this paper, the development history, material, manufacturing method, and post-processing technology of vascular stents are introduced. In particular, this paper focuses on the existing manufacturing technology and post-processing technology of vascular stents and the impact of these technologies on stent performance is described and discussed. Moreover, the future development of vascular stent manufacturing technology will be prospected and proposed.

show abstract

Section: Microstructuresmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Review on Manufacturing and Post-Processing Technology of Vascular Stents

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Although this laser-textured surface did not show an increased adhesion and proliferation of HUVECs, but the ability to reduce platelets adhesion, and increased migration to increase the initial endothelialisation could also contribute benefits. DLIP technique could also make spots array structure on real stents with modified wettability [ 24 ], reduced platelet adhesion [ 135 ] and controlled drug releasing [ 136 ]. These functions make DLIP a highly potential technique to improve stents performance.…”

Section: Laser Surface Modification On Stents and Stent-related Materialsmentioning

confidence: 99%

Surface engineering and the application of laser-based processes to stents - A review of the latest development

Dong

Pacella

Liu

et al. 2022

Bioactive Materials

View full text Add to dashboard Cite

Late in-stent thrombus and restenosis still represent two major challenges in stents’ design. Surface treatment of stent is attracting attention due to the increasing importance of stenting intervention for coronary artery diseases. Several surface engineering techniques have been utilised to improve the biological response in vivo on a wide range of biomedical devices. As a tailorable, precise, and ultra-fast process, laser surface engineering offers the potential to treat stent materials and fabricate various 3D textures, including grooves, pillars, nanowires, porous and freeform structures, while also modifying surface chemistry through nitridation, oxidation and coatings. Laser-based processes can reduce the biodegradable materials' degradation rate, offering many advantages to improve stents’ performance, such as increased endothelialisation rate, prohibition of SMC proliferation, reduced platelet adhesion and controlled corrosion and degradation. Nowadays, adequate research has been conducted on laser surface texturing and surface chemistry modification. Laser texturing on commercial stents has been also investigated and a promotion of performance of laser-textured stents has been proved. In this critical review, the influence of surface texture and surface chemistry on stents performance is firstly reviewed to understand the surface characteristics of stents required to facilitate cellular response. This is followed by the explicit illustration of laser surface engineering of stents and/or related materials. Laser induced periodic surface structure (LIPSS) on stent materials is then explored, and finally the application of laser surface modification techniques on latest generation of stent devices is highlighted to provide future trends and research direction on laser surface engineering of stents.

show abstract

“…38,39 In recent years, miR-126 has been widely used in modifying vascular stents to inhibit restenosis via promoting endothelialization. 40,41 Qu et al built a human saphenous vein culture model in vitro and a rat vein grafting model in vivo to evaluate the effect of miR-126-3p on improving the patency of vein graft. 42 Results showed that elevated miR-126-3p expression markedly promoted the proliferation and migration of VECs, accelerated re-endothelialization and reduced restenosis, which might be because miR-126-3p strengthened the extracellular signal-regulated kinase 1/2 (ERK1/2) and protein kinase B (AKT) signaling pathways through suppressing the expression of sprouty-related protein-1 (SPRED-1) and phosphatidylinositol 3-kinase regulatory subunit 2 (PIK3R2).…”

Section: Therapeutic Agents For Repairing Endotheliummentioning

confidence: 99%