Preparative isolation and purification of two amides from <i>Mallotus lianus</i> Croiz by high‐speed counter‐current chromatography

Jiang, Liyan; Lu, Yanbin; He, Shan; Pan, Yuanjiang; Sun, Cuirong; Wu, Tingfeng

doi:10.1002/jssc.200800396

Cited by 8 publications

(3 citation statements)

References 37 publications

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“…Flavonoids (52-85) have been reported from M. apelta (leaves and branches), M. barbatus (leaves), M. conspurcatus (roots), M. metcalfianus (leaves and stems), and M. japonicus (leaves) (Table 3). Chalcones (86)(87)(88)(89)(90)(91)(92)(93)(94)(95)(96)(97)(98)(99)(100)(101)(102)(103)(104) have been reported from M. philippinensis (fruits) and M. philippensis (fruits) (Table 4).…”

Section: Flavonoids and Chalconesmentioning

confidence: 99%

“…They were found in M. barbatus, M. cuneatus, M. furetianus, M. japonicus, M. lianus, M. macrostachyus, M. nudiflorus, and M. repandus (Table 15). 313 trans-2-carboxy-4-hydroxytetrahydrofuran N,N-dimethylamide M. cuneatus leaves [94] 314 nicotinamide M. japonicus leaves [95] 315 mallorepine M. repandus stems [96] 316 N-isobutyl-2E,4E,12Z-octadecatrienamide M. lianus roots [97] 317 (7Z,10Z,18Z)-tricosa-7,10,18-trienamide M. lianus roots [97] 318 phenazine C M. japonicus leaves [74] 319 cyclo(L-Pro-L-Leu) M. nudiflorus stems [98] 320 cyclo(D-trans-Hyp-D-Leu) M. nudiflorus stems [98] 321 cyclo(D-Pro-L-Phe) M. nudiflorus stems [98] 322 cyclo(D-cis-Hyp-L-Phe) M. nudiflorus stems [98] 323 3-hydroxy-4,5(R)-dimethyl-2(5H)-furanone M. furetianus leaves [8] 324 (Z)-3-hexenyl-β-D-glucopyranoside M. furetianus leaves [8,16] 325 benzyl-O-β-D-glucopyranoside M. macrostachyus leaves [77] Figure 16. Chemical structures of other compounds from Mallotus genus (312-325).…”

Section: Other Compoundsmentioning

confidence: 99%

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Genus mallotus (euphorbiaceae): a review on traditional medicinal use, phytochemistry and biological activities

Anh

Park

Trang³

et al. 2022

Vietnam J. Sci. Technol.

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Ethnopharmacological relevance: The genus Mallotus (Euphorbiaceae family) includes 124 accepted names and distributes in tropical and sub-tropical regions. Some Mallotus species are used in traditional medicines for the treatment of chronic hepatitis, enteritis stomach, disorders, cholelithiasis, anti-cancer, gastric, and duodenal ulcers. Aim of the study: According to the Scifinder database, this is the first review study that focuses on the phytochemistry and pharmacology of Mallotus genus (17 Mallotus species) to understand the link between the traditional medicinal uses, phytochemistry, and bioactivities. Thus, they provides a scientific fundamental for further research in the phytochemical and pharmacological activities of their species. Materials and methods: Information about the Mallotus genus was collected using various databases, such as Web of Science, SciFinder, PubMed, Sci-hub, Google Scholar, Wiley, Elsevier, ACS publications, and SpringerLink between 1978 and 2021. Plant names were validated by “The Plant List” (www.theplantlist.org). Results: Up to now, total 325 compounds were reported from Mallotus species, including phloroglucinols, steroids, coumarins, benzopyrans, flavonoids, chalcones, galics, and bergenins. The extracts and phytochemical constituents of the Mallotus genus are a rich source of biologically active, including anti-cancer, anti-inflammatory, immunoregulatory, antioxidant, antibacterial, antifungal, anti-virus, and other activities. Conclusions: The review indicated that the Mallotus genus is a promising source of biological activities compounds, special anti-cancer chromanes. The results of this review confirm the great potential of Mallotus species. Thus, it will be helpful for further research in the phytochemistry and pharmacology of the Mallotus genus.

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Section: Flavonoids and Chalconesmentioning

confidence: 99%

Section: Other Compoundsmentioning

confidence: 99%

Genus mallotus (euphorbiaceae): a review on traditional medicinal use, phytochemistry and biological activities

Anh

Park

Trang³

et al. 2022

Vietnam J. Sci. Technol.

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“…Leaves of Mallotus furetianus have been popularly consumed as aromatic tea and are used to treat hyperglycemia . Phytochemical investigation of plants in the Mallotus genus resulted in the isolation of a diverse array of compounds, such as terpenoids, diterpenes, phenols, flavonoids, lignans, and amide derivatives of fatty acids. − …”

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confidence: 99%

Mallotumides A–C: Potent Cytotoxic Cycloheptapeptides from the Roots of Mallotus spodocarpus

Sawektreeratana,

Krachangchaeng,

Pittayanurak

et al. 2023

Org. Lett.

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The structures of potent cytotoxic cycloheptapeptides, mallotumides A−C (1−3, respectively) isolated from the roots of Mallotus spodocarpus Airy Shaw, were elucidated by extensive spectroscopic analysis. The absolute configuration of 1 was determined by single-crystal X-ray crystallographic data. All three cycloheptapeptides exhibited potent cytotoxicity against various cancer cell lines with IC 50 values ranging from 0.60 to 4.02 nM.

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Separation of alkaloids from herbs using high‐speed counter‐current chromatography

Fang¹,

Liu²,

Yang³

et al. 2011

J of Separation Science

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Alkaloids represent a most widespread group of bioactive natural products. Because of their alkalinity and structural diversity, the fractionation and purification of the alkaloids from herbs can often present a number of practical difficulties using the conventional chromatographic techniques. High-speed counter-current chromatography (HSCCC) is a liquid-liquid partition chromatography with a support-free liquid stationary phase, and is gaining more and more popularity as a viable separation technique for bioactive compounds from natural resources. In the present review, focus is placed on the separation of alkaloids by both conventional HSCCC and pH-zone-refining counter-current chromatography (CCC) techniques from herbs. The review presents the separation of over 120 different alkaloid compounds from more than 30 plant species by the conventional HSCCC and pH-zone-refining CCC. Based on the data from the literature, the proper solvent systems for the separation of alkaloids by the conventional HSCCC and pH-zone-refining CCC are also summarized.

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Preparative isolation and purification of two amides from Mallotus lianus Croiz by high‐speed counter‐current chromatography

Cited by 8 publications

References 37 publications

Genus mallotus (euphorbiaceae): a review on traditional medicinal use, phytochemistry and biological activities

Genus mallotus (euphorbiaceae): a review on traditional medicinal use, phytochemistry and biological activities

Mallotumides A–C: Potent Cytotoxic Cycloheptapeptides from the Roots of Mallotus spodocarpus

Separation of alkaloids from herbs using high‐speed counter‐current chromatography

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