Preparative isolation and purification of seven main antioxidants from Eucommia ulmoides Oliv. (Du-zhong) leaves using HSCCC guided by DPPH-HPLC experiment

Dai, Xing-Ping; Huang, Qiong; Zhou, Boting; Gong, Zhicheng; Liu, Zhao‐Qian; Shi, Shuyun

doi:10.1016/j.foodchem.2013.02.006

Cited by 146 publications

(95 citation statements)

References 31 publications

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“…Genetic diversity of E. ulmoides E. ulmoides, the only extant species of Eucommiaceae, is one of the oldest and most effective herbal medicines, and is widely used for treatment of hypertension (Dai et al, 2013). Hence, to better conserve and utilize this endangered species, it is necessary to gather as great a diversity of material as possible.…”

Section: Discussionmentioning

confidence: 99%

“…With the Chinese name Du-zhong, the bark of E. ulmoides has been applied as a traditional Chinese medicine (TCM) for more than 2000 years. The major effective constituents of E. ulmoides include types of lignans, iridoids, phenylpropanoids, flavonoids, polysaccharides, and terpenes (Dai et al, 2013). E. ulmoides possesses the potential for multiple pharmacological applications, including nourishment of the liver and kidney, strengthening of the muscles and bones, prevention of the high risk of abortion, hypertension, and diabetes (Kwan et al, 2003;National Pharmacopoeia Committee, 2010).…”

Section: Introductionmentioning

confidence: 99%

“…Until now, a widespread artificial population has been mainly distributed in the Guizhou, Hubei, Henan, and Shaanxi provinces of China. E. ulmoides has rich genetic resources; however, previous studies have mainly focused on cultivation (Sun et al, 2013), Gutta-percha application (Suzuki et al, 2012), contents of active medicinal components (Dai et al, 2013), and pharmacological properties (Deyama et al, 2001). Thus, exploring the genetic diversity and population structure of E. ulmoides is very useful and important for its cultivation and production.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Genetic diversity and population structure of Eucommia ulmoides Oliver, an endangered medicinal plant in China

Yu¹,

Wang²,

Peng³

et al. 2015

Genet. Mol. Res.

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ABSTRACT. Eucommia ulmoides Oliver, one of the tertiary relict species found only in China, is the only extant species of Eucommiaceae. Using inter-simple sequence repeat (ISSR) and sequence-related amplified polymorphism (SRAP) markers, we studied the genetic diversity and population genetic structure of 187 accessions from 17 E. ulmoides populations throughout its main distribution in China. A total of 65 bands were amplified using eight ISSR primers, of which 50 bands (76.9%) were polymorphic. Meanwhile, another 244 bands were observed using eight SRAP primer combinations and 163 (66.8%) of these were polymorphic. The analysis of molecular variation (AMOVA) indicated that 88.8 and 92.4% of the total variation resided within populations based on ISSR and SRAP analysis, respectively. Moreover, we found that the E. ulmoides populations were clustered into six distinct groups using ISSR and SRAP markers via the unweighted pair-group method (UPGMA). Furthermore, STRUCTURE analysis showed that these 17 populations could be classified into four groups using ISSR markers, but only two groups using SRAP markers. No 2471-2483 (2015) significant relevancy was observed between genetic and geographic distances among the sampled populations. The results of this study support the view that exchange of seeds among local farmers plays an important role in shaping the present genetic distribution pattern. "Core collection" is suggested for genetic diversity conservation of E. ulmoides in China.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Genetic diversity and population structure of Eucommia ulmoides Oliver, an endangered medicinal plant in China

Yu¹,

Wang²,

Peng³

et al. 2015

Genet. Mol. Res.

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“…Some works dealing with the extraction and analysis of geniposidic acid from different plants have been carried out, such as high-pressure liquid chromatography (HPLC) analysis of water extraction from the leaves of Plantago asiatica (7), isolation antioxidants using HSCCC (8), comparison of methods for extraction of geniposidic acid from Eucommia ulmoides (9) and UPLC-MS analysis of the extract of Eucommia ulmodies (10). However, there is no report on the extraction of geniposidic acid from plantain seeds using supercritical fluid extraction (SFE).…”

Section: Introductionmentioning

confidence: 99%

Optimization of supercritical fluid extraction of geniposidic acid from plantain seeds using response surface methodology

Wang

Liu

Chang

2014

Green Chemistry Letters and Reviews

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The process parameters of supercritical CO 2 (SCCO 2 ) plus modifer for the extraction of geniposidic acid from plantain seeds were studied using a Box-Behnken design. The effects of independent variables, that is, ethanol concentration (0-70%, ethanol:water, v/v), extraction pressure (10-30 MPa), and temperature (50-80°C) on the yield of geniposidic acid were evaluated. Results indicated that the data could be well fitted to a second-order polynomial model. The effects of ethanol concentration and temperature, as well as the interaction between ethanol concentration and temperature were significant (p < 0.05). The yield (8.9 mg/g) of modified SCCO 2 extraction at optimal conditions was compared with that obtained by Soxhlet extraction or ultrasound assisted extraction.

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“…1) Water extracts from E. ulmoides leaves are a relatively potent antioxidant. 2) Geniposidic acid (GA) is the active component of E. ulmoides leaves and enhances the turnover rate of stratum corneum in false aged model rats.…”

mentioning

confidence: 99%

Herb extracts and collagen hydrolysate improve skin damage resulting from ultraviolet-induced aging in hairless mice

Jimbo

Kawada

Nomura

2015

Bioscience, Biotechnology, and Biochemistry

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We examined the effect of the daily ingestion of herb extract from Eucommia ulmoides leaves and Korean ginseng on skin damage induced by repeated UV irradiation of hairless mice. The herb extract was orally administered to mice at a dose of 1000 mg/kg/day. The hydration of mice dorsal skin decreased significantly with repeated UV irradiation, but did not decrease when the herb extract was administered for seven weeks. Transepidermal water loss (TEWL) increased with UV irradiation, but decreased with the administration of dietary herb extract. These effects were more pronounced when combined with the administration of collagen hydrolysate. Geniposidic acid from E. ulmoides leaves and ginsenoside Rg1 from Korean ginseng reduced TEWL and increased the skin moisture content of UV-damaged skin on hairless mice, respectively. We concluded that this dietary herb extract reduced the skin damage caused by UV-induced aging, with geniposidic acid and ginsenoside Rg1 detected in the blood.

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Preparative isolation and purification of seven main antioxidants from Eucommia ulmoides Oliv. (Du-zhong) leaves using HSCCC guided by DPPH-HPLC experiment

Cited by 146 publications

References 31 publications

Genetic diversity and population structure of Eucommia ulmoides Oliver, an endangered medicinal plant in China

Genetic diversity and population structure of Eucommia ulmoides Oliver, an endangered medicinal plant in China

Optimization of supercritical fluid extraction of geniposidic acid from plantain seeds using response surface methodology

Herb extracts and collagen hydrolysate improve skin damage resulting from ultraviolet-induced aging in hairless mice

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