An observational study, including 103 nurses of 2 hospitals in Sanandaj-Iran in 2007, carried out to determine how much nurses coped with their stress and to define the factors affecting stress management. They responded to questionnaires based on Adolescent Coping Orientation for Problem Experiences (A-COPE) with 3-Likert-scale responses. Stress management was positive in 67.9% and negative in 38.8% of nurses. This study showed managing stress depends not only to personality, but also to the work environment. Therefore, beside teaching nurses proper methods of stress management to strengthen their coping resources, attempts should be done to arrange work environments how to reduce sources of stress.