Presence of a fatty acid-binding protein in the armadillo Harderian gland

Histology, Histochemistry and Fine Structure of the Lacrimal and Nictitans Gland in the South American ArmadilloChaetophractus villosus (Xenarthra, Mammalia)

“…However, in the latter species the NG and HG are anatomically distinct glands, each one possessing its own secretory duct. Additionally, the HG of Chaetophractus possesses tubulo-alveolar endpieces with wide lumina and with lipid contents and secretion by exocytosis (Aldana Marcos et al, 1995;Aldana Marcos, 1996;Cavagnari et al, 1998;. These characteristics are shared with all mammals possessing HG (Sakai, 1981).…”

Proteome Profiling in the Rat Harderian Gland

“…There are 111 known fatty acid-binding proteins from different species with six isoforms: adipocyte- (A-FABP), brain- (B-FABP), epidermal-(E-FABP), heart- (H-FABP), intestinal-(I-FABP) and liver-specific FABP (L-FABP) involved in fatty acid uptake, transport, targeting, and modulating fatty acid concentration (= fatty-acid%20binding%20protein%20(FABP)%20family). FABP in the armadillo HG was reported for the first time in 1998 and suggested the presence of the heart-specific type of FABP by partial amino acid sequencing using Edman degradation after the sequence alignment . In this study, we identified two spots of FABP and MS/MS data unambiguously assigned both protein spots to epidermal type isoforms of FABP (E-FABP) (see Supporting Information Figure online).…”

“…FABP in the armadillo HG was reported for the first time in 1998 and suggested the presence of the heart-specific type of FABP by partial amino acid sequencing using Edman degradation after the sequence alignment. 37 In this study, we identified two spots of FABP and MS/MS data unambiguously assigned both protein spots to epidermal type isoforms of FABP (E-FABP) (see Supporting Information Figure 4 online). It is, however, possible that H-FABP was not detectable as a high abundance protein using our technique but the expression of E-FABP seems to be the predominant isoform in the rat HG due to its high abundance.…”

“…It is, however, possible that H-FABP was not detectable as a high abundance protein using our technique but the expression of E-FABP seems to be the predominant isoform in the rat HG due to its high abundance. Simply from inspection the abundance of E-FABP is also higher in HG than those of EABP in rat primary neurons (E- and H-FABP) and astrocytes (E-FABP), rat hippocampus (E-FABP), and human hippocampus (E- and B-FABP), based on previously constructed ref D maps using a comparable proteomics method.…”

The main fatty acid‐binding protein in the liver of the shark (Halaetunus bivius) belongs to the liver basic type

“…On the other hand, a given FABP type can be expressed in more than one tissue, such as the heart‐type (H‐FABP) which is also found in kidney, skeletal muscle, aorta, lung, mammary gland, placenta, brain, stomach, testes and adrenal glands [3]. We have also recently found a H‐FABP in a mammalian Harderian gland [4]. However, fish seem not to be included in this mammalian tissue specificity, as the first FABP isolated from a nonmammalian vertebrate (the liver of the nurse shark Ginglymostoma cirratum ) is structurally more closely related to mammalian H‐FABPs than to the members of the liver fatty acid‐binding protein (L‐FABP) subfamily [5].…”