Presence of Atrial Fibrillation Is Independently Associated With Adverse Outcomes in Patients Hospitalized With Heart Failure

Abstract

Background-It is unclear if the presence of atrial fibrillation (AF) on admission is associated with worse in-hospital outcomes in patients hospitalized with heart failure (HF

Clinical and Echocardiographic Factors Associated With New-Onset Atrial Fibrillation in Heart Failure – Subanalysis of the WARCEF Trial –

“…6,7,18, 19 Mountantonakis et al analyzed 99,810 patients hospitalized with HF, of whom one-third had AF, and reported longer hospital stay and higher mortality in AF patients as compared with those in sinus rhythm. 18 Indeed, patients with HF who subsequently develop AF have a higher mortality rate. 8,9,20 A Carvedilol or Metoprolol European Trial (COMET) sub-analysis showed that overall mortality was markedly increased when AF developed (relative risk, 1.9; P<0.0001).…”

Prognostic role of atrial fibrillation in patients affected by chronic heart failure. Data from the MECKI score research group

“…Yet, it remains unclear whether the association of AF and prognosis in HF is due to the consequences of the arrhythmia itself or to the fact that AF is usually associated with a more severe clinical status. Conflicting results on the prognostic role of AF in HF patients have been recently reported [9][10][11][12][13].…”

Prognostic Value of Cardiopulmonary Exercise Test in Elderly Women with Heart Failure and Reduced or Preserved Ejection Fraction

“…HF and atrial fibrillation share the same risk factors and together have a negative synergic impact on prognosis [16], increasing mortality and morbidity both in hospitalised [17] and community patients [16] [18], irrespective of LV function [10] [20]. The unfavourable effect of atrial fibrillation on outcome may be even stronger in women [19] and in HFpEF [20].…”