Pressure Dynamic Characteristics of Pressure Controlled Ventilation System of a Lung Simulator

Shi, Yan; Ren, Shuai; Cai, Maolin; Xu, Weiqing; Deng, Quan

doi:10.1155/2014/761712

Cited by 20 publications

(15 citation statements)

References 32 publications

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“…The air parameters in atmosphere normal reference is presented in Table . According to ISO 6358, mass flow equation can be obtained . The equation is as follows:

q = ({, \begin{array}{l} 0.001 \cdot n_{i} ρ_{ANR} C_{ϕ} p_{up} \sqrt{\frac{293}{T}} \frac{p_{italicdown}}{p_{italicup}} \leq b \\ 0.001 \cdot n_{i} ρ_{ANR} C_{ϕ} p_{up} \sqrt{\frac{293}{T}} \cdot \sqrt{1 - {(\frac{p_{down} / p_{up} - b}{1 - b})}^{2}} \frac{p_{italicdown}}{p_{italicup}} > b \end{array}),

…”

Section: Mathematical Model Of the Simulated Cough Devicementioning

confidence: 99%

ANSYS‐MATLAB co‐simulation of mucus flow distribution and clearance effectiveness of a new simulated cough device

Ren

Shi

Cai

et al. 2018

Numer Methods Biomed Eng

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Coughing is an irritable reaction that protects the respiratory system from infection and improves mucus clearance. However, for the patients who cannot cough autonomously, an assisted cough device is essential for mucus clearance. Considering the low efficiency of current assisted cough devices, a new simulated cough device based on the pneumatic system is proposed in this paper. Given the uncertainty of airflow rates necessary to clear mucus from airways, the computational fluid dynamics Eulerian wall film model and cough efficiency (CE) were used in this study to simulate the cough process and evaluate cough effectiveness. The Ansys-Matlab co-simulation model was set up and verified through experimental studies using Newtonian fluids. Next, model simulations were performed using non-Newtonian fluids, and peak cough flow (PCF) and PCF duration time were analyzed to determine their influence on mucus clearance. CE growth rate (λ) was calculated to reflect the CE variation trend. From the numerical simulation results, we find that CE rises as PCF increases while the growth rate trends to slow as PCF increases; when PCF changes from 60 to 360 L/min, CE changes from 3.2% to 51.5% which is approximately 16 times the initial value. Meanwhile, keeping a long PCF duration time could greatly improve CE under the same cough expired volume and PCF. The results indicated that increasing the PCF and PCF duration time can improve the efficiency of mucus clearance. This paper provides a new approach and a research direction for control strategy in simulated cough devices for airway mucus clearance.

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“…The air parameters in atmosphere normal reference is presented in Table . According to ISO 6358, mass flow equation can be obtained . The equation is as follows:

q = ({, \begin{array}{l} 0.001 \cdot n_{i} ρ_{ANR} C_{ϕ} p_{up} \sqrt{\frac{293}{T}} \frac{p_{italicdown}}{p_{italicup}} \leq b \\ 0.001 \cdot n_{i} ρ_{ANR} C_{ϕ} p_{up} \sqrt{\frac{293}{T}} \cdot \sqrt{1 - {(\frac{p_{down} / p_{up} - b}{1 - b})}^{2}} \frac{p_{italicdown}}{p_{italicup}} > b \end{array}),

…”

Section: Mathematical Model Of the Simulated Cough Devicementioning

confidence: 99%

ANSYS‐MATLAB co‐simulation of mucus flow distribution and clearance effectiveness of a new simulated cough device

Ren

Shi

Cai

et al. 2018

Numer Methods Biomed Eng

Self Cite

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“…Therefore, the value of pd/pu is always bigger than b (0.528). So the mathematical equations of mechanical ventilation system with double lungs can be got [38][39][40]:…”

Section: Mathematical Modeling Of Mechanical Ventilation System With mentioning

confidence: 99%

Dimensionless Study of Double Lungs on Secretion Clearance of a Pressure-Controlled Mechanical Ventilation System

2018

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“…Therefore, equations of flow, pressure, and volume are necessary to set up mathematical model of secretion clearance system 12,35,39 Pressure equation…”

Section: Modeling Of Secretion Clearance Systemmentioning

confidence: 99%

“…Initially, bacteria breeds easily in patients' respiratory system with accumulation of secretions, which may bring about pulmonary infection. [10][11][12][13][14][15][16][17][18][19][20][21][22] Furthermore, hypoventilation, 1 respiratory failure, and other relevant diseases may be caused by secretion in airway. [23][24][25][26][27] What is more, the most common disease is ventilator-associated pneumonia (VAP) in mechanical ventilation, whose incidence rate is about 68% and mortality rate is 50%-70%, [28][29][30][31][32] respectively.…”

Section: Introductionmentioning

confidence: 99%

Dimensionless simulation study on mechanical in-exsufflation secretion clearance systems with a volume-controlled ventilation function

Shen

Zhou

Wang

et al. 2017

Advances in Mechanical Engineering

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Secretion clearance is an important respiratory treatment for patients, who cannot cough out secretion spontaneously. Aiming at the disadvantages of existing secretion clearance technologies, in this article, we proposed two mechanical in-exsufflation secretion clearance systems (namely, pressure-controlled secretion clearance system and volume-controlled secretion clearance system) with a volume-controlled ear. To illustrate the dynamic characteristics of the two secretion clearance systems, a dimensionless mathematical model of the two secretion clearance systems was set up. After that the mathematical model was verified through experimental studies. To improve the efficiency and security of secretion clearance of the two secretion clearance systems, secretion clearance airflow dynamics of the two secretion clearance systems were studied and compared. Finally, influences of key parameters on the dynamic characteristics of the two secretion clearance systems are obtained. This article lays a foundation for the optimization of the two secretion clearance systems.

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Pressure Dynamic Characteristics of Pressure Controlled Ventilation System of a Lung Simulator

Cited by 20 publications

References 32 publications

ANSYS‐MATLAB co‐simulation of mucus flow distribution and clearance effectiveness of a new simulated cough device

ANSYS‐MATLAB co‐simulation of mucus flow distribution and clearance effectiveness of a new simulated cough device

Dimensionless Study of Double Lungs on Secretion Clearance of a Pressure-Controlled Mechanical Ventilation System

Dimensionless simulation study on mechanical in-exsufflation secretion clearance systems with a volume-controlled ventilation function

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