Pressure induced skin and soft tissue injury in the emergency department

Gamston, Julia

doi:10.1136/emermed-2018-207807

Cited by 17 publications

(29 citation statements)

References 18 publications

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“…As for mask-related discomfort, we recommend wearing a properly fitted mask and applying moisturizer or gel beforehand for lubrication. 28 We recommend nonirritating products for handwashing, and applying adhesive bandages on the portions of the skin in contact with the mask to help reduce friction. Because of the possibility of conjunctival transmission of COVID-19—first reported by a Chinese expert 29 and later confirmed by scientific studies 30 —we strongly recommend using face shields in conjunction with goggles.…”

Section: Discussionmentioning

confidence: 99%

The Physical and Psychological Effects of Personal Protective Equipment on Health Care Workers in Wuhan, China: A Cross-Sectional Survey Study

Xia¹,

Fu²,

Liao³

et al. 2020

Journal of Emergency Nursing

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The current literature on health care workers wearing personal protective equipment (PPE) indicates that they experience a wide variety of discomfort, especially for nurses in the emergency department. This article contributes mainly that the discomfort caused by wearing PPE could be classified into 7 categories: (1) dizziness, (2) dyspnea, (3) nausea, (4) micturition desire, (5) retroauricular pain, (6) thirst, and (7) inconvenience at work. More complaints about uncomfortable symptoms and pressure sores were reported by female physicians and nurses and by those working at designated hospitals or in intensive care units and working in PPE for more than 4 hours. Key implications for emergency nursing practice are that shorter time per shift, adequate protective products, and proper psychological interventions may be beneficial to relieve discomfort.

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Section: Discussionmentioning

confidence: 99%

The Physical and Psychological Effects of Personal Protective Equipment on Health Care Workers in Wuhan, China: A Cross-Sectional Survey Study

Xia¹,

Fu²,

Liao³

et al. 2020

Journal of Emergency Nursing

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“…Then, IRAK1 and TRAF are released, and the latter combines with transforming growth factor β activated kinase-1 (TAK1) and induces its activation, then activates transcription factors NF- κ B and AP1 or activates JNK to act on AP1, and finally produces a large number of biological effector molecules, such as TNF- α and IL-8, IL-1 β [ 25 – 28 ]. Therefore, TLR2/MyD88/NF- κ B signaling pathway plays an important role in infectious diseases and inflammatory diseases [ 29 ], and inhibiting TLR2 could treat soft tissue infections by inhibiting inflammation and protecting tissues [ 30 , 31 ].…”

Section: Discussionmentioning

confidence: 99%

Pharmacological Mechanisms of Shangke Huangshui against Skin and Soft Tissue Infection

Chen

Zheng

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Background. Skin and soft tissue infections (SSTIs) are a group of common diseases, usually caused by bacteria. Shangke Huangshui (SK) has been widely used to treat various SSTIs diseases for many years, but its mechanism is unclear. Therefore, this study was designed to investigate the anti-infective effect of SK on different skin and soft tissue infection diseases and to explore its underlying mechanism. Methods. The subcutaneous abscess mouse model, the dermal ulcer rat model, and the infectious soft tissue injury rat model were established by injection of Staphylococcus aureus to evaluate the anti-inflammatory and antibacterial effects of SK. Abscess volume, local appearance score and histological changes, bacterial contents, and hydroxyproline concentration in the skin or soft tissue were analyzed. The levels of NO, TNF-α, IL-1β, and IL-8 in the serum and tissue were determined by ELISA method. The mRNA expression levels of TLR2, MyD88, TAK1, NF-κB, AP-1, and other genes were measured with qRT-PCR method, and the protein expression of TLR2, MyD88, TAK1, NF-κB, and AP-1 was detected by western blot method. Results. SK had an obvious therapeutic effect on skin and soft tissue infections. It reduced the volume of abscess and promoted the healing of skin ulcer, improved pathological phenomena, such as inflammatory infiltration of skin and soft tissue, reduced the levels of white blood cells and NO in the blood, decreased bacteria contents in the skin and soft tissue. Furthermore, SK decreased the mRNA expression of TLR2, MyD88, TAK1, NF-κB and AP-1, and other related genes and also downregulated the protein expression of TLR2, MyD88, TAK1, NF-κB, and AP-1. Conclusion. The experiments provide evidence that SK can treat skin and soft tissue infection diseases based on its comprehensive antibacterial and anti-inflammatory effects. The therapeutic mechanism may be associated with the inhibition of TLR2/MyD88/NF-κB signaling pathway.

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“…This research will be of great significance to the treatment of stress soft tissue injury. 8 According to the time of risk exposure in youth team sports, Soomro n's team determined the overall efficacy of structured multi-level IPPs integrating warm-up and neuromuscular strength, and conducted a systematic review and meta-analysis of the literature in multiple databases. The results showed that in 10 studies including 9 RCTs, the IRR of the composite population point estimate was 0.60.…”

Section: Related Workmentioning

confidence: 99%

Application of Chen Yuangao in the Treatment of Soft Tissue Injury of Football Players

LiuYu

Gang

2021

Rev Bras Med Esporte

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The treatment of soft tissue injury in football players generally includes physical therapy, anti-inflammatory and analgesic drug treatment, surgical treatment and early rest immobilization. Western medicine treatment of soft tissue injury can quickly heal the wound and relieve pain in a short time. The treatment of traditional Chinese medicine is based on the whole and must seek the root of the disease. It is believed that the occurrence of certain diseases is related to Qi, blood, liver and kidney deficiency, so we should pay attention to the overall adjustment during treatment of symptoms. In view of this, this study analyzed the effect of Chen Yuan ointment, from traditional Chinese medicine, in the treatment of soft tissue injury. Sixty-eight football players who completed ankle ligament reconstruction were divided into four groups according to the type of operation and whether Chen Yuangao-assisted rehabilitation was used or not. The results showed that the Ankle Hindfoot Function Score and the visual analog scale (VAS) score of patients in the fibula brevis tendon reconstruction Chen Yuan ointment group were 98.3 and 0.3, respectively, at the last follow-up, which were better than those in other groups, and had lower pain scores. This result shows that Chen Yuangao has a certain effect in the treatment of soft tissue injury, which can provide a research idea for the rapid rehabilitation of football players.

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Pressure induced skin and soft tissue injury in the emergency department

Cited by 17 publications

References 18 publications

The Physical and Psychological Effects of Personal Protective Equipment on Health Care Workers in Wuhan, China: A Cross-Sectional Survey Study

The Physical and Psychological Effects of Personal Protective Equipment on Health Care Workers in Wuhan, China: A Cross-Sectional Survey Study

Pharmacological Mechanisms of Shangke Huangshui against Skin and Soft Tissue Infection

Application of Chen Yuangao in the Treatment of Soft Tissue Injury of Football Players

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