Preterm premature rupture of the membranes with fetal pulmonary maturity present: A prospective study

Spinnato, Joseph A.; Dc, Shaver; Bray, EM; Lipshitz, Jeffrey

doi:10.1016/0020-7292(87)90096-8

Cited by 33 publications

(49 citation statements)

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“…Multiparity is a risk factor for membrane rupture due to diminished membrane strength. Similar results were reported by Spinato et al [23] in 1987 and by Ekwo et al [24] in 1993. Multiparity is a risk factor for pPROM due to longstanding infection, previous trauma to cervix and patulous os.…”

Section: Discussion:-supporting

confidence: 91%

Effect of three regimens of prophylactic antibiotics in pregnant women with preterm premature rupture of fetal membranes: A randomised comparative study.

Arora¹,

Trivedi²,

Patra³

et al. 2017

IJAR

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Section: Discussion:-supporting

confidence: 91%

Effect of three regimens of prophylactic antibiotics in pregnant women with preterm premature rupture of fetal membranes: A randomised comparative study.

Arora¹,

Trivedi²,

Patra³

et al. 2017

IJAR

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“…Many previous studies evaluating the management of ruptured membranes were small and performed prior to the widespread implementation of maternal antibiotic administration to prolong latency and reduce short term morbidity, including neonatal infection. 14,[27][28][29][30][31][32] The PPROMT Trial results, together with the results of the recent PPROMEXIL studies, 20,21 suggest there are benefits from expectant management without incurring significant risk of harms. It may be possible that there are groups of women who benefit from immediate delivery.…”

Section: Discussionmentioning

confidence: 99%

Immediate delivery compared with expectant management after preterm pre-labour rupture of the membranes close to term (PPROMT trial): a randomised controlled trial

et al. 2016

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A note on versions:The version presented here may differ from the published version or from the version of record. If you wish to cite this item you are advised to consult the publisher's version. Please see the repository url above for details on accessing the published version and note that access may require a subscription.For more information, please contact eprints@nottingham.ac.uk 1 Immediate delivery compared with expectant management after preterm pre-labour rupture of the membranes close to term

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“…[9][10][11] Several studies have shown increased latency and increased rates of chorioamnionitis in late preterm PPROM women managed expectantly, but found no differences in major neonatal morbidity and mortality, regardless of whether testing for pulmonary maturity was performed. [12][13][14][15] A meta-analysis of these studies recommended an approach of immediate induction of labor for all PPROM women >30 weeks GA or with confirmed pulmonary maturity, although this was mainly shown to benefit maternal morbidity rather than improving neonatal outcome. 16 Long-term follow-up of infants born after PPROM demonstrated that the incidence of significant neurological disorders at 2 years of age was not modified by the length of the latency period 17 but more so by GA at birth, suggesting that an aggressive approach to PPROM after 30 weeks GA does not have a negative impact on neonatal and child development and may reduce fetal risks associated with increased latency to birth.…”

Section: Introductionmentioning

confidence: 99%

Neonatal outcomes are associated with latency after preterm premature rupture of membranes

et al. 2012

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Objective: To determine factors associated with latency time to birth after preterm premature rupture of membranes (PPROM) and the impact on neonatal outcomes.Study Design: Data on singleton pregnancies with PPROM (n ¼ 1535 infants) were prospectively collected in a computerized perinatal/neonatal database at a tertiary care perinatal center. Latency was characterized as p72h versus >72 h after PPROM.Result: The percentage of women with latency to birth >72 h decreased from 67% in very preterm (gestational age (GA) 25 to 28 weeks) to 10% in late preterm women (GA 33 to 36 weeks). PPROM women with latency p72 h were more likely to have pregnancy-induced hypertension and birth weight <3%; PPROM women with latency >72 h were more likely to have received steroids and develop clinical chorioamnionitis. PPROM <32 weeks GA with latency p72 h was associated with a two-fold higher incidence of severe neonatal morbidity, while PPROM between 29 to 34 weeks GA and latency p72 h was associated with a higher incidence of moderate neonatal morbidity. Conclusion:A latency period >72 h was associated with a decreased incidence of adverse neonatal outcomes up to 32 weeks GA for severe and 34 weeks GA for moderate morbidity indices.

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Preterm premature rupture of the membranes with fetal pulmonary maturity present: A prospective study

Cited by 33 publications

References 0 publications

Effect of three regimens of prophylactic antibiotics in pregnant women with preterm premature rupture of fetal membranes: A randomised comparative study.

Effect of three regimens of prophylactic antibiotics in pregnant women with preterm premature rupture of fetal membranes: A randomised comparative study.

Immediate delivery compared with expectant management after preterm pre-labour rupture of the membranes close to term (PPROMT trial): a randomised controlled trial

Neonatal outcomes are associated with latency after preterm premature rupture of membranes

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