Pretransplant Psychiatric and Medical Comorbidity of Alcoholic Liver Disease Patients Who Received Liver Transplant

Assessment of depression and anxiety in patients with chronic liver disease

“…Namely, in the patient with CLD, incidence of depression ranged from 20% to 70.6% 4, 6, 7, 12, 14-17 , and anxiety from 13% to 71.6% 6,14,17 . Similar data were obtained in the group of patients with chronic hepatitis C 27, 31-34 and in patients with alcoholic cirrhosis 18 .…”

“…Besides neuropathogenic impact of CLD 1, 5, 25 , such a high frequency of this mental disturbances might be explained by the fact that a majority of these patients belonging to a high risk population for developing psychiatric disorders (alcoholism, drug addiction, etc.) 17 .…”

“…Most of the previous studies have been focused on depression in CLD 4,6,7,12,[14][15][16][17] , while only a few have been devoted to anxiety in these patients 6,14,16,17 . Published studies data were heterogenic, both in terms of study population, different diagnostic criteria and assessment instruments that were used for the diagnosis of depression and anxiety.…”

Understanding alcohol misuse and comorbid psychiatric disorders

“…Patients undergoing liver transplant are such a group as untreated psychiatric conditions could influence the outcome of the transplant. DiMaritini et al [16] examined 112 pretransplant (liver) candidates with alcoholic liver disease for psychiatric disorders. Seventy percent of women and 61% of men had psychiatric disorders prior to transplant.…”

Liver Transplant—Psychiatric and Psychosocial Aspects

“…6,7 In most of such cases of ALD, diagnosis of alcohol dependence is tenable. 8 Debate has continued as to whether and when ALD patients should be considered for transplantation. Some argue from a moralistic standpoint that since alcohol had been consumed by a person willfully leading to complications, 9 so scarce grafts should not be expended on alcohol users.…”