Pretreatment social functioning predicts 1‐year outcome in early onset psychosis

Abstract

Results of this study suggest a strong longitudinal inter-relatedness between social functioning and negative symptoms in this age group. An integrative treatment approach including family interventions, social skills training, long-term specialized work/school rehabilitation, and adequate antipsychotic treatment is warranted to improve both, social functioning and negative symptoms.

Processing speed and executive functions predict real-world everyday living skills in adolescents with early-onset schizophrenia

“…Negative symptoms have also been described as having a moderating effect [13] and a mediator effect [15] in the relationship between cognition and psychosocial functioning. In EOS, some have found negative symptoms to predict functional outcome [26,27], but this result has not been found by others [25]. Our results showed that negative symptoms significantly correlated with real-world scores, but when considered along with cognition, cognitive variables emerged as stronger predictors.…”

“…Taking into account previous studies in EOS as well as studies in AOS suggesting specific determinants for everyday living skills and real-world behaviors [16,17], we expected verbal memory, processing speed, attention/working memory and executive functions to predict Life Skills Profile (LSP) scores. In accordance with previous findings regarding the associations between symptoms and functional outcome in EOS samples [25][26][27] and in AOS [18], we hypothesized that both positive and negative symptoms would emerge as significant predictors of real-world everyday living skills scores.…”

“…In a 13-year follow-up, Oie et al [23] found that baseline scores in executive function, memory, processing speed and attention were related to social and community functioning at follow-up. Among clinical variables, it has been reported that type of onset [24], and both positive [25] and negative symptoms [26,27] predict functional outcome in EOS.…”

Effectiveness of Integrated Care Including Therapeutic Assertive Community Treatment in Severe Schizophrenia Spectrum and Bipolar I Disorders

“…The high baseline rate of independent living may be explained by the fact that most of our patients had no support from sheltered homes and, thus, were severely ill enough to fulfill the inclusion criteria of ACCESS, while those living in sheltered homes already received enough support to be treated with standard (mostly outpatient) care. 35 The high rate of continuous independent living during ACCESS may be viewed as a success of ACCESS and related to the intensive work with significant others.…”

Patterns and Correlates of Expressed Emotion, Perceived Criticism, and Rearing Style in First Admitted Early-Onset Schizophrenia Spectrum Disorders

“…Future research should examine perceived criticism as a predictor of relapse and indicator of adolescents with EOS who need extended support and treatment. Rearing style should be carefully observed because of its link with patients' illness concept and, potentially, to service engagement and medication adherence.Key Words: Family, psychosis, adolescents, expressed emotion, perceived criticism, parental bonding (J Nerv Ment Dis 2014;202: 00-00) E arly-onset schizophrenia spectrum disorders (age of onset < 18 years; henceforth EOS) are associated with many negative outcomes, including worse premorbid functioning, longer duration of untreated psychosis (DUP), a higher number of negative symptoms at initial presentation, and lower response rates to and more side effects with antipsychotic treatment (Meng et al, 2006;Schimmelmann et al, 2007Schimmelmann et al, , 2013a. Furthermore, EOS seems to have distinguishable prodromal features (Fux et al, 2013;Schimmelmann et al, 2011Schimmelmann et al, , 2013b.…”