Prevalence and Antbiogram of Bacterial Isolates Causing Urinary Tract Infections at Federal Teaching Hospital Abakaliki I (FETHA I)

Alo, Moses Nnaemeka; Saidu, A. Y.; Ugah, Uchenna Iyioku; Al-Hassan, M. M.

doi:10.9734/bmrj/2015/16696

Cited by 13 publications

(23 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Those who were single at the time of the study had the highest prevalence of 64%, followed by those who were married -32%, while widows/widowers had 4%. This is similar to a previous report [25] chich reported that single individuals had the highest prevalence (44%), followed by those who were married (27%), divorced/separated (18%) and widows/widowers (11%). His is contrary to a study that reported the highest prevalence of UTIs among married women (66%), followed by those who were single (24%) [32].…”

Section: Discussionsupporting

confidence: 92%

“…With respect to occupation, students showed the highest prevalence(58%), followed by civil servants (16%), traders (14%) and the unemployed (8%), while farmers had the least prevalence (4%). This is similar to a report by [25] that showed studentsas having the highest prevalence rate (42%), followed by civil servants (30%), small traders (15%), and casual labourers who showed the least prevalence (13%). This report is not in agreement with findings in [33] where amall traders showed the highest prevalence rate (33%), followed by casual labourers (30%), civil servants (21%), and students showed the least (17%).…”

Section: Discussionsupporting

confidence: 90%

“…In the current study, the low incidence of urinary tract infection reported in Nsukka may be due to different clinical profiles, geographical location, and good hygiene level of the patients. E. coli was the common causative agent of UTI as reported in this study and in Rother studies [24,25,26]. This could be because it is the predominant bacteria in the gastrointestinal tract of humans, and other previous researches have shown E. coli to be the cause in 80-90% of casus of UTI.…”

Section: Discussionsupporting

confidence: 72%

“…The increasing frequency of prostate disease and diabetes mellitus in males are responsible for the increase in the the incidence of UTI in elderly patients. This report is similar to some studies [31,16] in chich a prevalence of 23.3% was reported in females aged 26-30 years, and in disagreement with another study that showed that female patients within the age range 37-47 years had the highest prevalence rate of 46.2%, followed by 26-36 years (31.1%), 15-25 years (18.2%) and above 48 years of age, showed the lowest prevalence of 4.5%, while among the male patients, 37-47 years showed the highest prevalence rate of 51.3%, followed by 26-36 years (29.5%), 15-25 years (14.1%), and above 48 years of age showed the lowest (5.1%) [25]. Statistical analysis showed that there was no significant difference between age and gender at 5% (P < 0.05).…”

Section: Discussionmentioning

confidence: 91%

See 3 more Smart Citations

Antibiotic suceptibility of<i> Escherichia coli</i> isolated in cases of urinary tract infection in Nsukka, Nigeria

Okafor¹,

Nweze²

2020

J Pre Clin Clin Res.

View full text Add to dashboard Cite

Introduction and objective. The study was carried out to determine the occurrence and antibiotics susceptibility profile of Escherichia coli recovered from patients with urinary tract infection (UTI) in Nsukka, southeastern Nigeria. Materials and method. Midstream urine samples were obtained from 266 outpatients. Standardized questionnaires were used to collect relevant information from the subjects. Urine samples were plated on MacConkey and eosin methylene blue agar. E. coli isolates were identified using standardized procedure. Kirby-Bauer disc diffusion method was used to determine the susceptibility of the isolates. Results. An overall UTI prevalence of 18.8% with 29 (19.30%) from females and 21 (18.10%) from males was observed. Females and males within the age range of 20-29 and 50-59 had the highest prevalence rate of 23.2% and 15%, respectively. The highest prevalence rate (26%) occurred in the Igbo-Etiti local government area, compared to the other four local government areas within the study locations. Urinalysis showed that 16 urine samples contained protein, 29 were nitrite positive and 31 were acidic. Most of the isolates were susceptible to nitrofurantoin (94%), ciprofloxacin (70%) and ofloxacin (78%) while all of them were completely resistant to cefuroxime, ceftazidime and augmentin (100%). All 50 (100%)E. coli isolates showed multiple resistance to three or more antibiotics with a resistance index ranging from 0.375-1.00. The MIC results showed that 17 (34%) isolates were sensitive to gentamicin (MIC ≤ 0.25µg/ml, MBC ≥ 128µg/ml), resistant to ciprofloxacin and ofloxacin. Conclusion. E. coli is predominantly associated with UTI in the study area and was susceptible to nitrofurantoin.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 72%

Section: Discussionmentioning

confidence: 91%

See 2 more Smart Citations

Antibiotic suceptibility of<i> Escherichia coli</i> isolated in cases of urinary tract infection in Nsukka, Nigeria

Okafor¹,

Nweze²

2020

J Pre Clin Clin Res.

View full text Add to dashboard Cite

show abstract

“…Worldwide, about 150 million people are diagnosed with UTI each year. 2 More than 95% of urinary tract infections are caused by a single bacterial species. E. coli is the most frequent infecting organism in acute infection.…”

Section: Introductionmentioning

confidence: 99%

Extended Spectrem Beta Lactamases among Multi Drug Resistant Gram Negetive Bacilli Causing Urinry Tract Infection

Bhattarai

Shrestha

Tiwari

2019

jhas

View full text Add to dashboard Cite

Extended Spectrum Beta Lactamases (ESBL), the main cause of resistance to broad spectrum β-lactams, among uropathogenic bacteria have increased over time raising a global concern in the therapeutic management of infections caused by these organisms. The study was carried out in Janamaitri Hospital, Kathmandu between December 2012 to May 2013 with an objective to determine the status of ESBL producing Gram negative bacilli isolated from the urine sample, collected from patients suspected of urinary tract infection. Gram negative bacilli isolated were tested for the presence of ESBL by combined disk and antibiotic susceptibility by Kirby Bauer disc diffusion method following Clinical and Laboratory Standard Institute guidelines. Among the total 1105 mid-stream urine samples, 256 Gram negative bacilli were isolated. By screening test using third generation cephalosporins, 156 isolates were screened as ESBL producers and 91 isolates were positive for ESBL test by combined disk method. Among the 91 (35.55%) ESBL producers, 70 (39.32%) Escherichia coli, 16 (44.44%) Klebsiella pneumoniae, and 5 (33.33%) Pseudomonas aeruginosa were found to be ESBL producers. Majority of ESBL producer showed resistance to ampicillin, co-trimoxazole, norfloxacin followed by ofloxacin. imipenem, amikacin and nitrofurantoin seemed to be the agent of choice for urinary tract infections when ESBL producers are susceptible to it. ESBL production found in these Gram negative bacilli with resultant microbial resistance to available cephalosporins and other agents may pose difficulties with the choice of therapeutic options for the treatment of severe infections.

show abstract

Pattern of Antimicrobial Resistance among Bacterial Isolates from Urogenital Clinical Specimens: A Descriptive Study from the Buea Health District, Cameroon

Amin

Njumkeng

Kika

et al. 2018

Drugs - Real World Outcomes

View full text Add to dashboard Cite

IntroductionAntimicrobial resistance has become a global concern and is particularly affecting developing countries where infectious diseases and poverty are endemic. The effectiveness of currently available antimicrobials is decreasing as a result of increasing resistant strains among clinical isolates.ObjectivesThe aim of this study was to determine the resistance pattern of bacterial isolates from different clinical urogenital specimens at different hospitals in the Buea Health District, Cameroon.MethodsA retrospective study was conducted in three hospital laboratories in the Buea Health District, Cameroon, from June to August 2017. All culture and antimicrobial susceptibility test results of patients who presented at each of the laboratories for urine, vaginal swab or urethral swab cultures from January 2012 to December 2016 were included in the study. Data were analysed using SPSS Windows version 20.0. The comparisons between different isolates’ resistance to antimicrobials were performed using the chi-square test. The difference in the resistance of urogenital isolates to various antimicrobials within different years was also compared by the chi-square test.ResultsA total of 423 bacterial isolates were obtained from clinical urogenital specimens such as: urine 93 (21.9%), vaginal swab 175 (41.4%) and urethral swab cultures 155 (36.6%). The predominant bacterial isolates were Staphylococcus spp. 320 (75.5%), Escherichia coli 37 (8.7%) and Enterococcus spp. 24 (5.7%). All the isolates showed significantly high resistance rates to amoxicillin/clavulanic acid (67.6% resistant rate, p = 0.025), but most isolates, except those of Staphylococcus, were relatively more susceptible to nitrofurantoin (82.6% susceptibility rate, p = 0.045). However, Staphylococcus spp. was more susceptible to ceftriaxone (91.0% susceptibility rate, p < 0.0001) and cefotaxime (74.4% susceptibility rate, p = 0.034). Generally, most of the isolates showed significantly rising rates of resistance to the majority of the antimicrobials tested from 2012 to 2017.ConclusionOur findings showed a progressively rising rate of antimicrobial resistance in urogenital bacterial isolates over the last 5 years in the Buea Health District. Thus, uncontrolled and irrational use or prescription of these drugs should be avoided to maintain low resistance of highly susceptible antimicrobials.

show abstract

Prevalence and Antbiogram of Bacterial Isolates Causing Urinary Tract Infections at Federal Teaching Hospital Abakaliki I (FETHA I)

Cited by 13 publications

References 34 publications

Antibiotic suceptibility of<i> Escherichia coli</i> isolated in cases of urinary tract infection in Nsukka, Nigeria

Antibiotic suceptibility of<i> Escherichia coli</i> isolated in cases of urinary tract infection in Nsukka, Nigeria

Extended Spectrem Beta Lactamases among Multi Drug Resistant Gram Negetive Bacilli Causing Urinry Tract Infection

Pattern of Antimicrobial Resistance among Bacterial Isolates from Urogenital Clinical Specimens: A Descriptive Study from the Buea Health District, Cameroon

Contact Info

Product

Resources

About