Prevalence and antifungal drug sensitivity of non-albicans Candida in oral rinse samples of self-caring elderly

Abstract

The possibility of oral reservoirs of NAC strains which are resistant to common antifungals should be noted in elderly outpatients.

Prevalence of Yeast Other than Candida albicans in Denture Wearers

“…The prevalence of the less common yeasts, other than C. albicans, in the oral cavity was observed in 33.3% of the colonized patients, corresponding to 13.5% of the whole population. This frequency is within the range of 9% to 20% previously reported in studies for noninstitutionalized patients, including in Portugal, the same geographic region . Hospitalized or immunosuppressed patients have a higher prevalence of non‐ C. albicans .…”

Antifungal agents commonly used in the superficial and mucosal candidiasis treatment: mode of action and resistance development

“…Emergence of resistant strains resulted in an increased mortality rate and therefore compelled the need for search for novel antimycotics and new potential drug targets. When Candida strains show reduced susceptibility to antifungal drugs [78], it is imperative to keep in mind the need for careful screening of drug resistance of Candida isolates among non- and hospitalized patients and this should be considered carefully by clinicians. In the treatment of mycotic diseases, detailed in vitro and in vivo studies are needed to specify the extent of their effectiveness.…”

Are oral and dental diseases linked to cancer?

“…We highlight the detection of non ‐albicans Candida strains in an increasing number of patients with oral carcinoma (Davies et al , 2002). These strains pose a future therapeutic challenge, given their greater resistance to antifungal drugs in comparison with C. albicans (Meurman et al , 2010).…”